D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 51 Citations 7,058 91 World Ranking 12818 National Ranking 5439

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Cell membrane

Her primary areas of study are Cell biology, Chloride channel, Cystic fibrosis transmembrane conductance regulator, Biochemistry and Biophysics. The Cell biology study combines topics in areas such as Bone canaliculus and Cartilage. Her Chloride channel study combines topics from a wide range of disciplines, such as Secretion, DIDS, Granule and Molecular biology.

Her Cystic fibrosis transmembrane conductance regulator research is multidisciplinary, incorporating elements of Syntaxin 3, Syntaxin 1, Respiratory burst, Phagosome acidification and Membrane protein. Deborah J. Nelson focuses mostly in the field of Biochemistry, narrowing it down to matters related to Epithelium and, in some cases, Osteoblast, Bone morphogenetic protein, Mesenchymal stem cell and Bone morphogenetic protein 2. Her Membrane potential study in the realm of Biophysics connects with subjects such as Cellular localization.

Her most cited work include:

  • CFTR regulates phagosome acidification in macrophages and alters bactericidal activity (365 citations)
  • Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms (204 citations)
  • Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia. (171 citations)

What are the main themes of her work throughout her whole career to date?

Deborah J. Nelson spends much of her time researching Cell biology, Biophysics, Membrane potential, Biochemistry and Chloride channel. Her research in Cell biology intersects with topics in Secretion, Syntaxin 3 and Cystic fibrosis transmembrane conductance regulator. Her Cystic fibrosis transmembrane conductance regulator course of study focuses on Cell membrane and Actin.

Her work deals with themes such as Endocrinology, Internal medicine, Calcium, Extracellular and Patch clamp, which intersect with Biophysics. Her Membrane potential research is multidisciplinary, incorporating perspectives in Electrophysiology, Reversal potential, Potassium channel, Membrane and Depolarization. The various areas that Deborah J. Nelson examines in her Chloride channel study include Sodium–hydrogen antiporter, Voltage clamp and Apoptosis.

She most often published in these fields:

  • Cell biology (39.36%)
  • Biophysics (32.98%)
  • Membrane potential (21.28%)

What were the highlights of her more recent work (between 2008-2020)?

  • Cell biology (39.36%)
  • Biophysics (32.98%)
  • Cystic fibrosis transmembrane conductance regulator (15.96%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Cell biology, Biophysics, Cystic fibrosis transmembrane conductance regulator, Secretion and Paracellular transport. Her Cell biology study integrates concerns from other disciplines, such as Biochemistry, Ion transporter and Osteoblast. Her work investigates the relationship between Biophysics and topics such as Phosphate that intersect with problems in Pyrophosphate.

Her work carried out in the field of Cystic fibrosis transmembrane conductance regulator brings together such families of science as Immune system, Transfection, Cell membrane, HEK 293 cells and Wild type. Her research integrates issues of Second messenger system, Mutant, Cytoskeleton, Actin and Phosphodiesterase in her study of Secretion. Her Paracellular transport research integrates issues from Patch clamp, Ion channel and Claudin.

Between 2008 and 2020, her most popular works were:

  • Osteoblast differentiation and bone matrix formation in vivo and in vitro (114 citations)
  • Disease-causing Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator Determine the Functional Responses of Alveolar Macrophages (85 citations)
  • Compartmentalized cyclic adenosine 3',5'-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains. (60 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cell membrane

Deborah J. Nelson mainly focuses on Cell biology, Secretion, Cystic fibrosis transmembrane conductance regulator, Chloride channel and Paracellular transport. Her studies in Cell biology integrate themes in fields like Epithelium, Bone canaliculus, Biochemistry, Osteoblast and Cartilage. Her Secretion research includes themes of Cell membrane, Cytoskeleton, Second messenger system, Phosphodiesterase and Actin.

Deborah J. Nelson has researched Cystic fibrosis transmembrane conductance regulator in several fields, including Phagosome, Mutant, Adenosine and Immunology. The concepts of her Chloride channel study are interwoven with issues in Synaptic vesicle, Neurotransmitter, Neural Inhibition, Neurotransmission and Hippocampus. Her research investigates the connection with Paracellular transport and areas like Barrier function which intersect with concerns in Ion channel.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

Anke Di;Mary E. Brown;Ludmila V. Deriy;Chunying Li.
Nature Cell Biology (2006)

529 Citations

Osteoblast differentiation and bone matrix formation in vivo and in vitro

Harry C. Blair;Quitterie C. Larrouture;Yanan Li;Hang Lin.
Tissue Engineering Part B-reviews (2016)

288 Citations

Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

Anjaparavanda P. Naren;Deborah J. Nelson;Weiwen Xie;Biljana Jovov.
Nature (1997)

258 Citations

Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia.

Chunying Li;Partha C. Krishnamurthy;Himabindu Penmatsa;Kevin L. Marrs.
Cell (2007)

229 Citations

Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

Sebastian Barg;Ping Huang;Lena Eliasson;Deborah J. Nelson.
Journal of Cell Science (2001)

226 Citations

Syntaxin 1A inhibits CFTR chloride channels by means of domain-specific protein–protein interactions

Anjaparavanda P. Naren;Michael W. Quick;James F. Collawn;Deborah J. Nelson.
Proceedings of the National Academy of Sciences of the United States of America (1998)

191 Citations

Regulation of Human CLC-3 Channels by Multifunctional Ca2+/Calmodulin-dependent Protein Kinase

Ping Huang;Jie Liu;Anke Di;Nicole C. Robinson.
Journal of Biological Chemistry (2001)

187 Citations

Single-channel recordings of apical membrane chloride conductance in A6 epithelial cells.

Deborah J. Nelson;John M. Tang;Lawrence G. Palmer.
The Journal of Membrane Biology (1984)

186 Citations

A process for controlling intracellular bacterial infections induced by membrane injury.

Deepannita Roy;David R. Liston;Vincent J. Idone;Anke Di.
Science (2004)

173 Citations

Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions.

Chunying Li;Keanna S. Dandridge;Anke Di;Kevin L. Marrs.
Journal of Experimental Medicine (2005)

163 Citations

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