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Biology and Biochemistry

D-Index
55
Citations
12686
World Ranking
14925
National Ranking
6247

Overview

Deborah J. Nelson is affiliated with the University of Chicago in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a specialized focus on molecular biology and several related subfields.

The main topics addressed in Deborah J. Nelson's work include:

  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Heterotopic Ossification and Related Conditions
  • RNA Interference and Gene Delivery
  • Parathyroid Disorders and Treatments
  • Bone health and treatments
  • Ion channel regulation and function

The scientist has published extensively on extracellular vesicles and their role in various diseases. Recent papers include:

  • Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases (2023), Journal of Extracellular Vesicles
  • Real time imaging of single extracellular vesicle pH regulation in a microfluidic cross-flow filtration platform (2022), Communications Biology
  • Kinetic Separation of Oxidative and Non-oxidative Metabolism in Single Phagosomes from Alveolar Macrophages: Impact on Bacterial Killing (2020), iScience
  • Phylogeny and chemistry of biological mineral transport (2020), Bone
  • Growth and mineralization of osteoblasts from mesenchymal stem cells on microporous membranes: Epithelial-like growth with transmembrane resistance and pH gradient (2021), Biochemical and Biophysical Research Communications

Deborah J. Nelson frequently collaborates with several researchers, including:

  • Vladimir Riazanski
  • Irina L. Tourkova
  • Paul H. Schlesinger
  • Harry C. Blair
  • Quitterie C. Larrouture

The most common venues for the scientist's work encompass:

  • iScience
  • Journal of Cellular Biochemistry
  • Journal of Extracellular Vesicles
  • Biochemical and Biophysical Research Communications
  • Communications Biology

Best Publications

  • Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis

    Laurent Meijer;Deborah J Nelson;Vladimir Riazanski;Aida G Gabdoulkhakova

  • CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

    Anke Di;Mary E. Brown;Ludmila V. Deriy;Chunying Li

  • Osteoblast differentiation and bone matrix formation in vivo and in vitro

    Harry C. Blair;Quitterie C. Larrouture;Yanan Li;Hang Lin

  • Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

    Anjaparavanda P. Naren;Deborah J. Nelson;Weiwen Xie;Biljana Jovov

  • Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia.

    Chunying Li;Partha C. Krishnamurthy;Himabindu Penmatsa;Kevin L. Marrs

  • Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

    Sebastian Barg;Ping Huang;Lena Eliasson;Deborah J. Nelson

  • Syntaxin 1A inhibits CFTR chloride channels by means of domain-specific protein–protein interactions

    Anjaparavanda P. Naren;Michael W. Quick;James F. Collawn;Deborah J. Nelson

  • Regulation of Human CLC-3 Channels by Multifunctional Ca2+/Calmodulin-dependent Protein Kinase

    Ping Huang;Jie Liu;Anke Di;Nicole C. Robinson

  • Single-channel recordings of apical membrane chloride conductance in A6 epithelial cells.

    Deborah J. Nelson;John M. Tang;Lawrence G. Palmer

  • A process for controlling intracellular bacterial infections induced by membrane injury.

    Deepannita Roy;David R. Liston;Vincent J. Idone;Anke Di

  • Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions.

    Chunying Li;Keanna S. Dandridge;Anke Di;Kevin L. Marrs

  • Disease-causing Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator Determine the Functional Responses of Alveolar Macrophages

    Ludmila V. Deriy;Erwin A. Gomez;Guangping Zhang;Daniel W. Beacham

  • Inositol 3,4,5,6-Tetrakisphosphate Inhibits the Calmodulin-dependent Protein Kinase II-activated Chloride Conductance in T84 Colonic Epithelial Cells

    Weiwen Xie;Marcia A. Kaetzel;Karol S. Bruzik;John R. Dedman

  • Membrane Capacitance Changes Associated with Particle Uptake during Phagocytosis in Macrophages

    Kathleen O. Holevinsky;Deborah J. Nelson

  • A role for annexin IV in epithelial cell function. Inhibition of calcium-activated chloride conductance.

    M. A. Kaetzel;Hsiao Chang Chan;W. P. Dubinsky;J. R. Dedman

  • The distribution, activity, and function of the cilia in the frog brain

    Deborah J. Nelson;Ernest M. Wright

  • Structural determinant for assembly of mammalian K+ channels.

    T.E. Lee;L.H. Philipson;A. Kuznetsov;D.J. Nelson

  • Calcium signaling in cultured rat oligodendrocytes

    Margaret Takeda;Deborah J. Nelson;Betty Soliven

  • CFTR chloride channels are regulated by a SNAP-23/syntaxin 1A complex

    Estelle Cormet-Boyaka;Anke Di;Steven Y. Chang;Anjaparavanda P. Naren

  • Annexin IV inhibits calmodulin-dependent protein kinase II-activated chloride conductance. A novel mechanism for ion channel regulation.

    Hsiao Chang Chan;M. A. Kaetzel;A. L. Gotter;J. R. Dedman

Frequent Co-Authors

Louis H. Philipson
Louis H. Philipson University of Chicago
Harry C. Blair
Harry C. Blair University of Pittsburgh
Jerrold R. Turner
Jerrold R. Turner Brigham and Women's Hospital
Paul H. Schlesinger
Paul H. Schlesinger Washington University in St. Louis
Stephen B. Shears
Stephen B. Shears National Institutes of Health
Laurent Meijer
Laurent Meijer Perha Pharmaceuticals
Michael W. Quick
Michael W. Quick University of Southern California
Mark W. Musch
Mark W. Musch University of Chicago
John R. Dedman
John R. Dedman University of Cincinnati Medical Center
Barry G. W. Arnason
Barry G. W. Arnason University of Chicago

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