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Biology and Biochemistry

D-Index
63
Citations
11038
World Ranking
10454
National Ranking
796

Overview

Patrick G. Bray is affiliated with the Liverpool School of Tropical Medicine in the United Kingdom. Their research primarily focuses on medicine, with a notable concentration in infectious diseases, pharmacology, neurology, public health, environmental and occupational health, as well as computational theory and mathematics.

The scientist's work extensively covers several topics associated with COVID-19, including clinical research studies, SARS-CoV-2 and COVID-19 research, antibiotics pharmacokinetics and efficacy, and SARS-CoV-2 detection and testing. Additional areas of interest include long-term effects of COVID-19, mosquito-borne diseases and control, and computational drug discovery methods.

Frequent collaborators in their research projects include Usman Arshad, Henry Pertinez, Helen Box, Lee Tatham, and Rajith K. R. Rajoli. These coauthors have partnered with Bray on multiple publications, reflecting consistent joint contributions in their fields of study.

Publication venues prominently featuring Patrick G. Bray's work include bioRxiv (Cold Spring Harbor Laboratory), Clinical Pharmacology & Therapeutics, British Journal of Clinical Pharmacology, and L'"esprit créateur/ L'"Esprit créateur.

The scientist has contributed to several research papers, including:

  • Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics, 2020, Clinical Pharmacology & Therapeutics
  • Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis, 2020, British Journal of Clinical Pharmacology
  • Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate plasma and target site concentrations derived from their established human pharmacokinetics, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Taste and Democracy in Nineteenth-Century French Literature and Thought, 2025, L'"esprit créateur/ L'"Esprit créateur

Best Publications

  • Artemisinins target the SERCA of Plasmodium falciparum

    U. Eckstein-Ludwig;R. J. Webb;I. D. A. van Goethem;J. M. East

  • 4-Aminoquinolines—Past, present, and future; A chemical perspective

    P M O'Neill;P G Bray;S R Hawley;S A Ward

  • Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

    Patrick G. Bray;Michael P. Barrett;Stephen A. Ward;Harry P. de Koning

  • A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance

    Viswanathan Lakshmanan;Patrick G Bray;Dominik Verdier-Pinard;David J Johnson

  • Access to Hematin: The Basis of Chloroquine Resistance

    Patrick G. Bray;Mathirut Mungthin;Robert G. Ridley;Stephen A. Ward

  • Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance.

    Patrick G. Bray;Rowena E. Martin;Leann Tilley;Stephen A. Ward

  • Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

    David J. Johnson;David J. Johnson;David A. Fidock;Mathirut Mungthin;Viswanathan Lakshmanan

  • Relationship between Antimalarial Drug Activity, Accumulation, and Inhibition of Heme Polymerization in Plasmodium falciparum In Vitro

    Shaun R. Hawley;Patrick G. Bray;Mathirut Mungthin;Jill D. Atkinson

  • Plant homologs of the Plasmodium falciparum chloroquine-resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses

    Spencer C. Maughan;Maciej Pasternak;Narelle Cairns;Guy Kiddle

  • P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

    Jones K;Bray Pg;Khoo Sh;Davey Ra

  • Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum.

    Patrick G. Bray;Omar Janneh;Kaylene J. Raynes;Mathirut Mungthin

  • Quinolines and Artemisinin: Chemistry, Biology and History

    Patrick Bray;Stephen Ward;P. M O'Neill

  • Isoquine and Related Amodiaquine Analogues: A New Generation of Improved 4-Aminoquinoline Antimalarials

    Paul M O'Neill;Amira Mukhtar;Paul A Stocks;Laura E Randle

  • Novel Short Chain Chloroquine Analogues Retain Activity Against Chloroquine Resistant K1 Plasmodium falciparum

    Paul A Stocks;Kaylene J Raynes;Patrick G Bray;B Kevin Park

  • Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria.

    Giancarlo A. Biagini;Parnpen Viriyavejakul;Paul M. O'Neill;Patrick G. Bray

  • Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.

    Paul M O'Neill;Richard K Amewu;Gemma L Nixon;Fatima Bousejra ElGarah

  • Acidification of the Malaria Parasite's Digestive Vacuole by a H+-ATPase and a H+-pyrophosphatase

    Kevin J. Saliba;Richard J.W. Allen;Stephanie Zissis;Patrick G. Bray

  • Evidence for a Common Non‐Heme Chelatable‐Iron‐Dependent Activation Mechanism for Semisynthetic and Synthetic Endoperoxide Antimalarial Drugs

    Paul A Stocks;Patrick G Bray;Victoria E Barton;Mohammed Al-Helal

  • Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues.

    Stephen Hindley;Stephen A Ward;Richard C Storr;Natalie L Searle

  • An Integrated Model of Chloroquine Action

    H Ginsburg;S.A Ward;P.G Bray

Frequent Co-Authors

Stephen A. Ward
Stephen A. Ward Liverpool School of Tropical Medicine
Paul M. O'Neill
Paul M. O'Neill University of Liverpool
B. Kevin Park
B. Kevin Park University of Liverpool
Saye Khoo
Saye Khoo University of Liverpool
David Back
David Back University of Liverpool
Neil G. Berry
Neil G. Berry University of Liverpool
Kiaran Kirk
Kiaran Kirk Australian National University
David G. Spiller
David G. Spiller University of Manchester
Michael R. H. White
Michael R. H. White University of Manchester
David A. Fidock
David A. Fidock Columbia University

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