World's Best Scientists 2026 revealed!
Song-Hai Shi

Song-Hai Shi

D-Index & Metrics

Neuroscience

D-Index
45
Citations
13534
World Ranking
6802
National Ranking
106

Overview

Song-Hai Shi is affiliated with Tsinghua University in China, where their research focuses extensively on neuroscience and molecular biology. The body of work spans several specialized fields including cellular and molecular neuroscience, developmental neuroscience, cell biology, and cognitive neuroscience. Their publications also cover broad topics such as neurogenesis and neuroplasticity mechanisms, photoreceptor and optogenetics research, neuroscience and neural engineering, neuroscience and neuropharmacology research, microtubule and mitosis dynamics, RNA research and splicing, as well as single-cell and spatial transcriptomics.

The scientist has contributed to numerous research papers published in a variety of respected venues. Frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Opinion in Neurobiology
  • Nature
  • Science Advances
  • Proceedings of the National Academy of Sciences

Recent papers authored or co-authored by Song-Hai Shi cover a spectrum of topics in neuroscience and biomedical engineering. Selected publications include:

  • "Centrosome anchoring regulates progenitor properties and cortical formation," 2020, Nature
  • "Bioresorbable thin-film silicon diodes for the optoelectronic excitation and inhibition of neural activities," 2022, Nature Biomedical Engineering
  • "Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex," 2022, Nature Neuroscience
  • "Patterned cPCDH expression regulates the fine organization of the neocortex," 2022, Nature
  • "Behavior and lineage progression of neural progenitors in the mammalian cortex," 2020, Current Opinion in Neurobiology

Collaborations feature regularly with multiple frequent co-authors, notably:

  • Jian Ma
  • Shuhan Hu
  • Jiajun Yang
  • Yunxiang Huang
  • Huachun Wang

The interdisciplinary nature of their research bridges neuroscience and biochemistry, genetics, and molecular biology. The prevalence of topics related to neurogenesis, neural engineering, and molecular mechanisms highlights a focus on understanding fundamental processes governing nervous system development and function.

Best Publications

  • Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction

    Yasunori Hayashi;Song Hai Shi;José A. Esteban;Antonella Piccini

  • Rapid Spine Delivery and Redistribution of AMPA Receptors After Synaptic NMDA Receptor Activation

    Song-Hai Shi;Yasunori Hayashi;Ronald S. Petralia;Shahid H. Zaman

  • Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons.

    Song-Hai Shi;Yasunori Hayashi;Yasunori Hayashi;José A. Esteban;Roberto Malinow

  • PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity

    José A. Esteban;Song Hai Shi;Christopher Wilson;Mutsuo Nuriya

  • Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity

    Song-Hai Shi;Lily Yeh Jan;Yuh-Nung Jan

  • Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors.

    Stuart M. Chambers;Yuchen Qi;Yuchen Qi;Yvonne Mica;Gabsang Lee

  • Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

    Xiaoqun Wang;Jin Wu Tsai;Janice H. Imai;Janice H. Imai;Wei Nan Lian

  • Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex

    Peng Gao;Maria Pia Postiglione;Teresa G. Krieger;Luisirene Hernandez;Luisirene Hernandez

  • Mammalian Par3 Regulates Progenitor Cell Asymmetric Division via Notch Signaling in the Developing Neocortex

    Ronald S. Bultje;David R. Castaneda-Castellanos;David R. Castaneda-Castellanos;Lily Yeh Jan;Yuh-Nung Jan

  • Specific synapses develop preferentially among sister excitatory neurons in the neocortex.

    Yong-Chun Yu;Ronald S. Bultje;Ronald S. Bultje;Xiaoqun Wang;Song-Hai Shi

  • APC and GSK-3β Are Involved in mPar3 Targeting to the Nascent Axon and Establishment of Neuronal Polarity

    Song-Hai Shi;Tong Cheng;Lily Yeh Jan;Yuh-Nung Jan

  • Clonally related visual cortical neurons show similar stimulus feature selectivity

    Ye Li;Hui Lu;Hui Lu;Pei-lin Cheng;Shaoyu Ge

  • Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly

    Yong-Chun Yu;Shuijin He;She Chen;Yinghui Fu

  • Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells

    Yuchen Qi;Yuchen Qi;Xin-Jun Zhang;Nicolas Renier;Zhuhao Wu

  • Two-photon imaging in living brain slices.

    Z.F Mainen;M Maletic-Savatic;S.H Shi;Y Hayashi

  • Cortical neurogenesis in the absence of centrioles

    Ryan Insolera;Hisham Bazzi;Wei Shao;Kathryn V Anderson

  • Common Molecular Pathways Mediate Long-Term Potentiation of Synaptic Excitation and Slow Synaptic Inhibition

    Cindy Shen Huang;Song-Hai Shi;Jernej Ule;Matteo Ruggiu

  • Clonal Production and Organization of Inhibitory Interneurons in the Neocortex

    Keith N. Brown;She Chen;Zhi Han;Zhi Han;Chun-Hui Lu

  • Specification of functional cranial placode derivatives from human pluripotent stem cells

    Stuart Chambers;Lorenz Studer;Zehra Dincer

  • The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis.

    Wenfei Kang;Li Chin Wong;Song Hai Shi;Jean M. Hébert

  • Production and organization of neocortical interneurons

    Khadeejah T Sultan;Khadeejah T Sultan;Keith N Brown;Keith N Brown;Song-Hai Shi

Frequent Co-Authors

Roberto Malinow
Roberto Malinow University of California, San Diego
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco
William B. Dobyns
William B. Dobyns University of Minnesota
Liqun Luo
Liqun Luo Stanford University
Karel Svoboda
Karel Svoboda Allen Institute
Arnold R. Kriegstein
Arnold R. Kriegstein University of California, San Francisco
Alexandra L. Joyner
Alexandra L. Joyner Memorial Sloan Kettering Cancer Center
Friedhelm Hildebrandt
Friedhelm Hildebrandt Boston Children's Hospital
Eric C. Lai
Eric C. Lai Memorial Sloan Kettering Cancer Center

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