D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 100 Citations 41,940 177 World Ranking 684 National Ranking 439
Best female scientists D-index 108 Citations 44,699 207 World Ranking 608 National Ranking 374

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Genetics
  • Mutation

Alexandra L. Joyner mostly deals with Cell biology, Genetics, GLI3, Gene and Sonic hedgehog. Her studies in Cell biology integrate themes in fields like Internal medicine, Endocrinology and Anatomy. Her Anatomy research integrates issues from Central nervous system and Neurogenins.

Her GLI3 research includes elements of Cancer research and Hedgehog signaling pathway, GLI2. Her biological study deals with issues like Molecular biology, which deal with fields such as Candidate gene, Polydactyly and Greig cephalopolysyndactyly syndrome. She has included themes like Adult stem cell, GSK-3, Stem cell, Repressor and Notochord in her Sonic hedgehog study.

Her most cited work include:

  • A gene expression atlas of the central nervous system based on bacterial artificial chromosomes (1715 citations)
  • Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons (951 citations)
  • A Mouse Model of Greig Cephalopolysyndactyly Syndrome: The extra-toesJ Mutation Contains an Intragenic Deletion of the Gli3 Gene (652 citations)

What are the main themes of her work throughout her whole career to date?

Cell biology, Cerebellum, Neuroscience, Genetics and Sonic hedgehog are her primary areas of study. Her Cell biology study combines topics in areas such as FGF8 and Anatomy. Her research in Anatomy intersects with topics in Ectoderm and Central nervous system.

The concepts of her Cerebellum study are interwoven with issues in Granule cell, Cell type, engrailed and Midbrain. Her Sonic hedgehog study combines topics from a wide range of disciplines, such as Medulloblastoma, Cancer research, GLI3, Internal medicine and Stem cell. Her GLI3 research incorporates themes from GLI1 and GLI2.

She most often published in these fields:

  • Cell biology (58.43%)
  • Cerebellum (40.45%)
  • Neuroscience (32.21%)

What were the highlights of her more recent work (between 2017-2021)?

  • Cerebellum (40.45%)
  • Cell biology (58.43%)
  • Progenitor cell (14.61%)

In recent papers she was focusing on the following fields of study:

Alexandra L. Joyner mostly deals with Cerebellum, Cell biology, Progenitor cell, Sonic hedgehog and Neuroscience. Her Cerebellum research incorporates elements of Granule cell, Rhombic lip, Human brain, Regulator and Epigenetics. The Neurogenesis, Hedgehog signaling pathway and Indian hedgehog research she does as part of her general Cell biology study is frequently linked to other disciplines of science, such as Choroid, therefore creating a link between diverse domains of science.

Her research integrates issues of Molecular biology, Age dependent and Regeneration in her study of Progenitor cell. Her studies deal with areas such as Medulloblastoma and Cancer research as well as Sonic hedgehog. In her work, Gene, Locus and Computational biology is strongly intertwined with Cell type, which is a subfield of Neuroscience.

Between 2017 and 2021, her most popular works were:

  • Childhood cerebellar tumours mirror conserved fetal transcriptional programs (153 citations)
  • CSF-1 controls cerebellar microglia and is required for motor function and social interaction (60 citations)
  • Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice (25 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Mutation

Alexandra L. Joyner focuses on Cell biology, Sonic hedgehog, Cerebellum, Neurogenesis and Progenitor cell. She studies Cell biology, focusing on Hedgehog signaling pathway in particular. Her work on PTCH1, Patched and Smoothened as part of general Hedgehog signaling pathway study is frequently linked to Choroid, bridging the gap between disciplines.

The study incorporates disciplines such as Medulloblastoma, Granule cell, Cell type and Cerebellar cortex in addition to Sonic hedgehog. The Cerebellum study combines topics in areas such as Excitatory postsynaptic potential, Neuron and Conditional gene knockout. In her study, which falls under the umbrella issue of Progenitor cell, Olfactory bulb, Notum, Wnt signaling pathway and Cell is strongly linked to Neural stem cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

Shiaoching Gong;Chen Zheng;Martin L. Doughty;Kasia Losos.
Nature (2003)

1918 Citations

Inactivation of the mouse Huntington's disease gene homolog Hdh.

MP Duyao;AB Auerbach;A Ryan;F Persichetti.
Science (1995)

947 Citations

In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog

Sohyun Ahn;Alexandra L. Joyner;Alexandra L. Joyner.
Nature (2005)

911 Citations

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

H. L. Park;C. Bai;K. A. Platt;Michael Matise.
Development (2000)

767 Citations

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

C. Brian Bai;C. Brian Bai;Wojtek Auerbach;Wojtek Auerbach;Joon S. Lee;Joon S. Lee;Daniel Stephen;Daniel Stephen.
Development (2002)

703 Citations

The knockout mouse project

Christopher P. Austin;James F. Battey;Allan Bradley;Maja Bucan.
Nature Genetics (2004)

677 Citations

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.

Yong Pan;Chunyang Brian Bai;Chunyang Brian Bai;Alexandra L. Joyner;Baolin Wang.
Molecular and Cellular Biology (2006)

666 Citations

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

R. Mo;A. M. Freer;D. L. Zinyk;M. A. Crackower.
Development (1997)

655 Citations

Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development

Alexandra L. Joyner.
Trends in Genetics (1996)

618 Citations

Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes.

Achim Gossler;Alexandra L. Joyner;Janet Rossant;William C. Skarnes.
Science (1989)

611 Citations

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