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Genetics

D-Index
98
Citations
42565
World Ranking
801
National Ranking
403

Research.com Recognitions

  • 2016 - Member of the National Academy of Sciences
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Nathaniel Heintz is a researcher affiliated with Rockefeller University in the United States. Their scientific work spans the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience, with a specific focus on Molecular Biology, Cellular and Molecular Neuroscience, Genetics, Neurology, and Ecology. The research topics covered include Genetic Neurodegenerative Diseases, Animal Genetics and Reproduction, Bacteriophages and microbial interactions, Receptor Mechanisms and Signaling, Mitochondrial Function and Pathology, Neuroscience and Neuropharmacology Research, and CRISPR and Genetic Engineering.

Heintz has contributed frequently to several publication venues. The most common platforms include bioRxiv (Cold Spring Harbor Laboratory), Cold Spring Harbor Protocols, Proceedings of the National Academy of Sciences, Nature, and Molecular Psychiatry.

Among their recent scholarly articles are the following:

  • Parallel ascending spinal pathways for affective touch and pain, 2020, Nature
  • Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis, 2020, Neuron
  • Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum, 2024, Nature Genetics
  • Serotonin receptor 4 in the hippocampus modulates mood and anxiety, 2021, Molecular Psychiatry
  • Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation, 2020, Nature Neuroscience

Their research collaborations include frequent coauthors such as Shiaoching Gong, Thomas S. Carroll, Christina Pressl, Kärt Mätlik, and Laura Kus.

Nathaniel Heintz has been recognized for their scientific contributions through membership in distinguished organizations. They became a Member of the National Academy of Sciences in 2016 and a Fellow of the American Association for the Advancement of Science (AAAS) in 2006.

Best Publications

  • The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

    Skirmantas Kriaucionis;Nathaniel Heintz

  • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.

    Zhenyu Yue;Shengkan Jin;Chingwen Yang;Arnold J. Levine

  • A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

    Shiaoching Gong;Chen Zheng;Martin L. Doughty;Kasia Losos

  • MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system

    Marian Mellen;Pinar Ayata;Scott Dewell;Skirmantas Kriaucionis

  • Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

    Hsiao Tuan Chao;Hongmei Chen;Rodney C. Samaco;Mingshan Xue;Mingshan Xue

  • A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

    Myriam Heiman;Anne Schaefer;Shiaoching Gong;Jayms D. Peterson

  • Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.

    Shiaoching Gong;Martin Doughty;Carroll R. Harbaugh;Alexander Cummins

  • Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.

    Yun Zhong;Qing Jun Wang;Qing Jun Wang;Xianting Li;Ying Yan

  • Radial glia serve as neuronal progenitors in all regions of the central nervous system.

    Todd E Anthony;Corinna Klein;Gord Fishell;Nathaniel Heintz

  • Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

    Joseph P. Doyle;Joseph D. Dougherty;Myriam Heiman;Eric F. Schmidt

  • IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

    Alana G. Lerner;John Paul Upton;P. V.K. Praveen;Rajarshi Ghosh

  • The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

    Lishi Li;Michael Rutlin;Victoria E. Abraira;Colleen Cassidy

  • The knockout mouse project

    Christopher P. Austin;James F. Battey;Allan Bradley;Maja Bucan

  • Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.

    Xiangdong W. Yang;Peter Model;Nathaniel Heintz

  • Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS

    Lei Feng;Mary E. Hatten;Nathaniel Heintz

  • MECHANISMS OF NEURAL PATTERNING AND SPECIFICATION IN THE DEVELOPING CEREBELLUM

    Mary E. Hatten;Nathaniel Heintz

  • Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor gene

    Jian Zuo;Philip L. De Jager;Kanji A. Takahashi;Weining Jiang

  • Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle.

    N Heintz;H L Sive;R G Roeder

  • Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

    Colin Fletcher;Nathaniel Heintz;Robert G. Roeder

  • IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

    Alana G. Lerner;John-Paul Upton;P.V.K. Praveen;Rajarshi Ghosh

Frequent Co-Authors

Paul Greengard
Paul Greengard Rockefeller University
Robert G. Roeder
Robert G. Roeder Rockefeller University
Mary E. Hatten
Mary E. Hatten Rockefeller University
Philip L. De Jager
Philip L. De Jager Columbia University
Eric Klann
Eric Klann New York University
Zhenyu Yue
Zhenyu Yue Icahn School of Medicine at Mount Sinai
Jian Zuo
Jian Zuo Creighton University
Brian T. Chait
Brian T. Chait Rockefeller University
Gord Fishell
Gord Fishell Harvard Medical School
David D. Ginty
David D. Ginty Howard Hughes Medical Institute

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