2019 - Fellow of the Royal Society, United Kingdom
The scientist’s investigation covers issues in Sonic hedgehog, Cell biology, Neural tube, Neural tube patterning and Neuroscience. His Sonic hedgehog study combines topics from a wide range of disciplines, such as Progenitor cell, Morphogen and Nervous system. His Morphogen research is multidisciplinary, incorporating elements of Cellular differentiation, Pattern formation and Gene regulatory network.
Cell biology and PAX6 are commonly linked in his work. His studies in Neural tube integrate themes in fields like Hedgehog signaling pathway, Transcription factor, Floor plate and Anatomy. His biological study spans a wide range of topics, including Homeobox, Embryonic stem cell, Vertebrate, Regulation of gene expression and Neural stem cell.
Cell biology, Neural tube, Neuroscience, Sonic hedgehog and Morphogen are his primary areas of study. His research in Cell biology intersects with topics in Genetics and Cellular differentiation. His Neural tube research incorporates elements of Progenitor cell, Progenitor, Transcription factor and Anatomy.
The study incorporates disciplines such as Regulation of gene expression and Vertebrate in addition to Neuroscience. His work in Sonic hedgehog covers topics such as Floor plate which are related to areas like Neural plate. The various areas that James Briscoe examines in his Morphogen study include Body Patterning, Signalling, Pattern formation and Gene regulatory network.
James Briscoe mostly deals with Cell biology, Progenitor cell, Embryonic stem cell, Gene regulatory network and Computational biology. His Cell biology research includes themes of Cell cycle, In vitro and Transcription factor. His Progenitor cell study combines topics in areas such as Neurogenesis, Cell type and Neural crest.
The study incorporates disciplines such as Neural tube, MRNA Sequencing and Neuroscience in addition to Cell type. His Neural tube research incorporates elements of Regulation of gene expression, Progenitor, Gene expression and Pattern formation. His Smoothened study combines topics from a wide range of disciplines, such as Sonic hedgehog, Morphogen and G protein-coupled receptor.
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A homeodomain protein code specifying progenitor cell identity and neuronal fate in the ventral neural tube
Thomas M. Jessell;James Briscoe;Johan Ericson;Johan Ericson.
The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe;Pascal P. Thérond;Pascal P. Thérond.
Nature Reviews Molecular Cell Biology (2013)
Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling
J Ericson;P Rashbass;A Schedl;S Brenner-Morton.
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction
Mathias Müller;James Briscoe;Carl Laxton;Dmitry Guschin.
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
J. Briscoe;L. Sussel;P. Serup;D. Hartigan-O'Connor.
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network.
Eric Dessaud;Andrew P. McMahon;James Briscoe.
Specification of neuronal fates in the ventral neural tube.
James Briscoe;Johan Ericson.
Current Opinion in Neurobiology (2001)
Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism
Eric Dessaud;Lin Lin Yang;Lin Lin Yang;Katy Hill;Barny Cox.
The interpretation of morphogen gradients.
Hilary L. Ashe;James Briscoe.
A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.
D Guschin;N Rogers;J Briscoe;B Witthuhn.
The EMBO Journal (1995)
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