What is he best known for?
The fields of study he is best known for:
- Gene
- Transcription factor
- Genetics
The scientist’s investigation covers issues in Sonic hedgehog, Cell biology, Neural tube, Neural tube patterning and Neuroscience.
His Sonic hedgehog study combines topics from a wide range of disciplines, such as Progenitor cell, Morphogen and Nervous system.
His Morphogen research is multidisciplinary, incorporating elements of Cellular differentiation, Pattern formation and Gene regulatory network.
Cell biology and PAX6 are commonly linked in his work.
His studies in Neural tube integrate themes in fields like Hedgehog signaling pathway, Transcription factor, Floor plate and Anatomy.
His biological study spans a wide range of topics, including Homeobox, Embryonic stem cell, Vertebrate, Regulation of gene expression and Neural stem cell.
His most cited work include:
- A homeodomain protein code specifying progenitor cell identity and neuronal fate in the ventral neural tube (1047 citations)
- The mechanisms of Hedgehog signalling and its roles in development and disease. (990 citations)
- Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling (884 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Neural tube, Neuroscience, Sonic hedgehog and Morphogen are his primary areas of study.
His research in Cell biology intersects with topics in Genetics and Cellular differentiation.
His Neural tube research incorporates elements of Progenitor cell, Progenitor, Transcription factor and Anatomy.
The study incorporates disciplines such as Regulation of gene expression and Vertebrate in addition to Neuroscience.
His work in Sonic hedgehog covers topics such as Floor plate which are related to areas like Neural plate.
The various areas that James Briscoe examines in his Morphogen study include Body Patterning, Signalling, Pattern formation and Gene regulatory network.
He most often published in these fields:
- Cell biology (42.00%)
- Neural tube (33.00%)
- Neuroscience (28.50%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (42.00%)
- Progenitor cell (13.00%)
- Embryonic stem cell (8.50%)
In recent papers he was focusing on the following fields of study:
James Briscoe mostly deals with Cell biology, Progenitor cell, Embryonic stem cell, Gene regulatory network and Computational biology.
His Cell biology research includes themes of Cell cycle, In vitro and Transcription factor.
His Progenitor cell study combines topics in areas such as Neurogenesis, Cell type and Neural crest.
The study incorporates disciplines such as Neural tube, MRNA Sequencing and Neuroscience in addition to Cell type.
His Neural tube research incorporates elements of Regulation of gene expression, Progenitor, Gene expression and Pattern formation.
His Smoothened study combines topics from a wide range of disciplines, such as Sonic hedgehog, Morphogen and G protein-coupled receptor.
Between 2017 and 2021, his most popular works were:
- Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord. (101 citations)
- CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog (71 citations)
- Nervous System Regionalization Entails Axial Allocation before Neural Differentiation (65 citations)
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
