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D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
35312
World Ranking
3251
National Ranking
99

Overview

Chi-chung Hui is affiliated with the University of Toronto in Canada. Their research spans broadly in the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. The subfields they focus on include Molecular Biology, Physiology, Cancer Research, Surgery, and Cardiology and Cardiovascular Medicine.

The scientist's recent publications cover a range of topics and are published in reputable journals. Notable papers include:

  • Identification of ALK in Thinness, 2020, published in Cell
  • Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches, 2020, Nature Communications
  • The transcriptional landscape of Shh medulloblastoma, 2021, Nature Communications
  • Time-restricted eating with or without low-carbohydrate diet reduces visceral fat and improves metabolic syndrome: A randomized trial, 2022, Cell Reports Medicine
  • Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation, 2020, Cell Reports

The main research topics associated with their work include:

  • Single-cell and spatial transcriptomics
  • Adipose Tissue and Metabolism
  • RNA Research and Splicing
  • Cancer-related molecular mechanisms research
  • Adipokines, Inflammation, and Metabolic Diseases
  • Epigenetics and DNA Methylation
  • Cancer Cells and Metastasis

Chi-chung Hui frequently publishes in specific venues such as:

  • Nature Communications
  • Cell Reports
  • Proceedings of the National Academy of Sciences
  • Science Advances
  • bioRxiv (Cold Spring Harbor Laboratory)

They often collaborate with several co-authors, including:

  • Joe Eun Son
  • Kyoung-Han Kim
  • Zhengchao Dou
  • Xi Huang
  • Xiaoyun Zhang

Best Publications

  • Angiotensin-converting enzyme 2 protects from severe acute lung failure

    Yumiko Imai;Keiji Kuba;Shuan Rao;Yi Huan

  • FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

    Melina Claussnitzer;Simon N. Dankel;Kyoung Han Kim;Gerald Quon

  • Notch1 functions as a tumor suppressor in mouse skin.

    Michael Nicolas;Anita Wolfer;Kenneth Raj;J Alain Kummer

  • Hedgehog signaling in development and cancer.

    Jin Jiang;Chi chung Hui

  • Mutations in SUFU predispose to medulloblastoma

    Michael D. Taylor;Ling Liu;Corey Raffel;Chi-chung Hui

  • A dermal niche for multipotent adult skin-derived precursor cells

    Karl J. L. Fernandes;Ian A. McKenzie;Ian A. McKenzie;Pleasantine Mill;Kristen M. Smith

  • A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

    Hiroshi Sasaki;Chi Chung Hui;Masato Nakafuku;Hisato Kondoh

  • The Tumor Suppressor Gene Brca1 Is Required for Embryonic Cellular Proliferation in the Mouse

    Razqallah Hakem;Razqallah Hakem;José Luis de la Pompa;José Luis de la Pompa;Christian Sirard;Christian Sirard;Rong Mo

  • Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

    H. L. Park;C. Bai;K. A. Platt;Michael Matise

  • SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

    Gen-Sheng Feng;Chi-Chung Hui;Tony Pawson

  • Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling.

    Hiroshi Sasaki;Yuriko Nishizaki;Chi Chung Hui;Masato Nakafuku

  • A Mouse Model of Greig Cephalopolysyndactyly Syndrome: The extra-toesJ Mutation Contains an Intragenic Deletion of the Gli3 Gene

    Chi-chung Hui;Alexandra L. Joyner;Alexandra L. Joyner

  • Gli Proteins in Development and Disease

    Chi-chung Hui;Stephane Angers

  • Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

    R. Mo;A. M. Freer;D. L. Zinyk;M. A. Crackower

  • Expression of three mouse homologs of the drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm-and mesoderm-derived tissues suggests multiple roles during postimplantation development

    Chi Chung Hui;Diane Slusarski;Kenneth A. Platt;Robert Holmgren

  • Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus

    Jun Motoyama;Jason Liu;Rong Mo;Qi Ding

  • Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.

    Qi Ding;Jun Motoyama;Stéphan Gasca;Rong Mo

  • The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants

    Zoë Hardcastle;Rong Mo;Chi-chung Hui;Paul T. Sharpe

  • Basal cell carcinomas in mice overexpressing Gli2 in skin

    Marina Grachtchouk;Rong Mo;Sandy Yu;Xiaoyun Zhang

  • Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment.

    Valerie P.I. Vidal;Marie-Christine Chaboissier;Susanne Lützkendorf;George Cotsarelis

Frequent Co-Authors

Andras Nagy
Andras Nagy Lunenfeld-Tanenbaum Research Institute
Josef M. Penninger
Josef M. Penninger University of British Columbia
Hiroshi Sasaki
Hiroshi Sasaki Jikei University School of Medicine
Benoit G. Bruneau
Benoit G. Bruneau Gladstone Institutes
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Brandon J. Wainwright
Brandon J. Wainwright University of Queensland
Masato Nakafuku
Masato Nakafuku Cincinnati Children's Hospital Medical Center
Janet Rossant
Janet Rossant University of Toronto
Benjamin A. Alman
Benjamin A. Alman Duke University
Stephen W. Scherer
Stephen W. Scherer University of Toronto

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