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Molecular Biology

D-Index
61
Citations
17221
World Ranking
1888
National Ranking
941

Overview

Jin Jiang is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily falls within the broad area of Biochemistry, Genetics, and Molecular Biology, with a significant focus on molecular biology and genetics as well as cell biology and immunology. Specific subfields also include cellular and molecular neuroscience.

The research topics covered by Jin Jiang include studies on the Hedgehog signaling pathway, epigenetics and DNA methylation, and Hippo pathway signaling involving YAP/TAZ proteins. Additional topics include invertebrate immune response mechanisms, neurobiology and insect physiology, genetic and kidney cyst diseases, and developmental biology with gene regulation.

Recent publications authored or co-authored by Jin Jiang include:

  • Hedgehog signaling mechanism and role in cancer, 2021, Seminars in Cancer Biology
  • YAP inhibits ERα and ER+ breast cancer growth by disrupting a TEAD-ERα signaling axis, 2022, Nature Communications
  • Hippo-Independent Regulation of Yki/Yap/Taz: A Non-canonical View, 2021, Frontiers in Cell and Developmental Biology
  • YAP antagonizes TEAD-mediated AR signaling and prostate cancer growth, 2023, The EMBO Journal
  • Damage-induced regeneration of the intestinal stem cell pool through enteroblast mitosis in the Drosophila midgut, 2022, The EMBO Journal

Jin Jiang's work has been published frequently in several scientific journals, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Methods in Molecular Biology
  • Frontiers in Cell and Developmental Biology
  • The EMBO Journal

Collaboration is a notable aspect of Jin Jiang's scientific activity, with frequent co-authors including Yuhong Han, Mengmeng Zhou, Yong Suk Cho, Shu Zhuo, and Aiguo Tian. These partners have contributed to multiple projects and publications over time.

Best Publications

  • Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

    Jin Jiang;Gary Struhl

  • Hedgehog signaling in development and cancer.

    Jin Jiang;Chi chung Hui

  • The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control.

    Lei Zhang;Fangfang Ren;Qing Zhang;Yongbin Chen

  • Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

    Hai Song;Kinglun Kingston Mak;Lilia Topol;Kangsun Yun

  • Signal-induced ubiquitination of IκBα by the F-box protein Slimb/β-TrCP

    Erika Spencer;Jin Jiang;Zhijian J. Chen

  • Tissue Damage-Induced Intestinal Stem Cell Division in Drosophila

    Alla Amcheslavsky;Jin Jiang;Y. Tony Ip

  • The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos.

    J. Jiang;D. Kosman;Y. T. Ip;Michael Steven Levine

  • The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis.

    Jianhang Jia;Wensheng Zhang;Bing Wang;Richard Trinko

  • Protein kinase A and hedgehog signaling in Drosophila limb development.

    Jin Jiang;Gary Struhl

  • Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

    Jin Jiang;Michael Levine

  • Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I.

    Jianhang Jia;Chao Tong;Bing Wang;Liping Luo

  • Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime

    Hyuk Wan Ko;Jin Jiang;Isaac Edery

  • Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

    Jianhang Jia;Kazuhito Amanai;Gelin Wang;Jiong Tang

  • Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

    Joel M. Hyman;Ari J. Firestone;Vivi M. Heine;Yun Zhao

  • Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways.

    Fangfang Ren;Bing Wang;Tao Yue;Eun Young Yun;Eun Young Yun

  • Hedgehog regulates smoothened activity by inducing a conformational switch

    Yun Zhao;Chao Tong;Chao Tong;Jin Jiang

  • A Hedgehog-Induced BTB Protein Modulates Hedgehog Signaling by Degrading Ci/Gli Transcription Factor

    Qing Zhang;Lei Zhang;Bing Wang;Chan Yen Ou

  • Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened

    Yongbin Chen;Noriaki Sasai;Guoqiang Ma;Tao Yue

  • Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms

    Fangfang Ren;Lei Zhang;Lei Zhang;Jin Jiang

  • Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail

    Jianhang Jia;Chao Tong;Jin Jiang

Frequent Co-Authors

Y. Tony Ip
Y. Tony Ip University of Massachusetts Chan Medical School
Qing Zhang
Qing Zhang Nanyang Technological University
Michael S. Levine
Michael S. Levine Princeton University
Gary Struhl
Gary Struhl Columbia University
Yingzi Yang
Yingzi Yang Harvard University
Yi Lu
Yi Lu University of Illinois at Urbana-Champaign
Bing Su
Bing Su Shanghai Jiao Tong University
Shuo Lin
Shuo Lin University of California, Los Angeles
James K. Chen
James K. Chen Stanford University
Bin Gao
Bin Gao National Institutes of Health

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