World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
19144
World Ranking
11727
National Ranking
5045

James K. Chen publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where James K. Chen sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 145 publications — 24th percentile

24% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

James K. Chen D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where James K. Chen sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 60 D-Index — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 1998 - Fellow of American Physical Society (APS) Citation For innovative and unique research in chaos and nonlinear dynamics, and in the evolution of largescale solar plasma eruptions and their impact on the magnetosphere

Overview

James K. Chen is affiliated with Stanford University in the United States. Their research spans multiple fields, primarily focusing on Medicine, as well as Biochemistry, Genetics, and Molecular Biology. Within these fields, their work delves into several specialized subfields including Molecular Biology, Oncology, Mechanical Engineering, Materials Chemistry, and Cancer Research.

Their scholarly output includes contributions to various research topics such as:

  • Cancer Genomics and Diagnostics
  • Hedgehog Signaling Pathway Studies
  • Epigenetics and DNA Methylation
  • Advanced biosensing and bioanalysis techniques
  • Colorectal Cancer Surgical Treatments
  • Colorectal Cancer Screening and Detection
  • Welding Techniques and Residual Stresses

James K. Chen frequently publishes in venues like bioRxiv (Cold Spring Harbor Laboratory), JCI Insight, Nature Chemical Biology, Science and Technology of Welding & Joining, and Cancer Research. These publications reflect a range of interdisciplinary research interests.

Selected recent papers authored or coauthored by this scientist include:

  • Organic wastewater treatment by a single-atom catalyst and electrolytically produced H2O2, 2020, Nature Sustainability
  • A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients, 2021, JCI Insight
  • Lanthanide-Based Optical Probes of Biological Systems, 2020, Cell Chemical Biology
  • Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata, 2021, JCI Insight
  • HIPK4 is essential for murine spermiogenesis, 2020, eLife

Throughout their research career, James K. Chen has collaborated extensively with several frequent coauthors, including Zhiping Feng, Jiapeng Huang, Marisa E. Hom, Alison E. Ondrus, and Alexander Deiters.

James K. Chen was recognized as a Fellow of the American Physical Society (APS) in 1998, for innovative and unique research in chaos and nonlinear dynamics, and in the evolution of largescale solar plasma eruptions and their impact on the magnetosphere.

Best Publications

  • Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.

    James K. Chen;Jussi Taipale;Michael K. Cooper;Philip A. Beachy

  • Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

    Jussi Taipale;James K. Chen;Michael K. Cooper;Baolin Wang

  • Structural basis for the binding of proline-rich peptides to SH3 domains

    Hongtao Yu;James K. Chen;Sibo Feng;David C. Dalgarno

  • Small molecule modulation of Smoothened activity.

    James K. Chen;Jussi Taipale;Keith E. Young;Tapan Maiti

  • Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.

    Sibo Feng;James K. Chen;Hongtao Yu;Julian A. Simon

  • Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade

    David M. Berman;Sunil S. Karhadkar;Andrew R. Hallahan;Joel I. Pritchard

  • Organic wastewater treatment by a single-atom catalyst and electrolytically produced H2O2.

    Jinwei Xu;Xueli Zheng;Zhiping Feng;Zhiyi Lu

  • Stromal response to Hedgehog signaling restrains pancreatic cancer progression.

    John J. Lee;Rushika M. Perera;Huaijun Wang;Dai-Chen Wu

  • Purmorphamine activates the Hedgehog pathway by targeting Smoothened

    Surajit Sinha;James K Chen

  • Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

    Ari J. Firestone;Joshua S. Weinger;Maria Maldonado;Kari Barlan

  • Intracranial Dural Arteriovenous Fistulas: Classification, Imaging Findings, and Treatment

    Dheeraj Gandhi;J. Chen;M. Pearl;J. Huang

  • The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

    Alex J. Kuo;Jikui Song;Jikui Song;Peggie Cheung;Satoko Ishibe-Murakami

  • Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

    Joel M. Hyman;Ari J. Firestone;Vivi M. Heine;Yun Zhao

  • Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2

    Wei Chen;Xiu-Rong Ren;Christopher D. Nelson;Larry S. Barak

  • A small molecule that binds Hedgehog and blocks its signaling in human cells

    Benjamin Z Stanton;Lee F Peng;Lee F Peng;Nicole Maloof;Kazuo Nakai

  • A crucial requirement for Hedgehog signaling in small cell lung cancer

    Kwon Sik Park;Luciano G. Martelotto;Martin Peifer;Martin L. Sos

  • Light-controlled gene silencing in zebrafish embryos

    Ilya A Shestopalov;Surajit Sinha;Surajit Sinha;James K Chen

  • An inducible long noncoding RNA amplifies DNA damage signaling.

    Adam M Schmitt;Julia T Garcia;Tiffany Hung;Ryan A Flynn

  • Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage

    Jason Yi;Xufeng Wu;Andrew H. Chung;James K. Chen

  • Small-molecule inhibitors of the AAA1 ATPase motor cytoplasmic dynein

    Ari J. Firestone;Joshua S. Weinger;Maria Maldonado;Kari Barlan

Frequent Co-Authors

Philip A. Beachy
Philip A. Beachy Stanford University
Stuart L. Schreiber
Stuart L. Schreiber Harvard University
Tarun M. Kapoor
Tarun M. Kapoor Rockefeller University
Maxence V. Nachury
Maxence V. Nachury University of California, San Francisco
Jussi Taipale
Jussi Taipale University of Cambridge
Vladimir I. Gelfand
Vladimir I. Gelfand Northwestern University
Tomas Cihlar
Tomas Cihlar Gilead Sciences (United States)
Joshua E. Elias
Joshua E. Elias Stanford University
Hongtao Yu
Hongtao Yu The University of Texas Southwestern Medical Center
Choung U. Kim
Choung U. Kim Bristol-Myers Squibb (Germany)

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing James K. Chen

Trending Scientists

Recently Published Articles