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Ariel Ruiz i Altaba

Ariel Ruiz i Altaba

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
16410
World Ranking
15387
National Ranking
284

Overview

Ariel Ruiz i Altaba is affiliated with the University of Geneva in Switzerland and specializes in fields related to Biochemistry, Genetics, and Molecular Biology.

The main subfields of study they have contributed to include:

  • Molecular Biology
  • Biotechnology
  • Cell Biology
  • Cancer Research
  • Oncology

The central topics of their research work are:

  • RNA Interference and Gene Delivery
  • Cell death mechanisms and regulation
  • Cancer Research and Treatments
  • Hippo pathway signaling and YAP/TAZ
  • Cancer Genomics and Diagnostics
  • Cancer Cells and Metastasis

They have published papers in the venue Cell Reports, with two recent publications including the following:

  • On the origin of metastases: Induction of pro-metastatic states after impending cell death via ER stress, reprogramming, and a cytokine storm (2022, Cell Reports)
  • Functional Pro-metastatic Heterogeneity Revealed by Spiked-scRNAseq Is Shaped by Cancer Cell Interactions and Restricted by VSIG1 (2020, Cell Reports)

Frequent collaborators include:

  • Marianna Silvano
  • Arwen Conod
  • Carolina Bernal-Morales
  • Yann Tapponnier
  • Santosh Anand

Best Publications

  • HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity

    Virginie Clement;Pilar Sanchez;Nicolas de Tribolet;Ivan Radovanovic

  • Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

    H. Roelink;A. Augsburger;J. Heemskerk;V. Korzh

  • The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

    Daniel C. Weinstein;Ariel Ruiz i Altaba;William S. Chen;Pamela Hoodless

  • Gli and hedgehog in cancer: tumours, embryos and stem cells

    Ariel Ruiz i Altaba;Pilar Sánchez;Nadia Dahmane;Nadia Dahmane

  • Sonic hedgehog controls stem cell behavior in the postnatal and adult brain.

    Verónica Palma;Daniel A. Lim;Nadia Dahmane;Pilar Sánchez;Pilar Sánchez

  • Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

    Pilar Sanchez;Ana Maria Hernández;Barbara Stecca;Andrea J. Kahler

  • Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

    Barbara Stecca;Christophe Mas;Virginie Clement;Marie Zbinden

  • The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis

    Nadia Dahmane;Nadia Dahmane;Pilar Sánchez;Pilar Sánchez;Yorick Gitton;Yorick Gitton;Verónica Palma;Verónica Palma

  • Human colon cancer epithelial cells harbour active HEDGEHOG‐GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

    Frédéric Varnat;Arnaud Duquet;Monica Malerba;Marie Zbinden

  • Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features

    Erich Roessler;Yang-Zhu Du;Jose L. Mullor;Esther Casas

  • Hedgehog-Gli signalling and the growth of the brain.

    Ariel Ruiz i Altaba;Verónica Palma;Nadia Dahmane

  • NANOG regulates glioma stem cells and is essential in vivo acting in a cross‐functional network with GLI1 and p53

    Marie Zbinden;Arnaud Duquet;Aiala Lorente-Trigos;Sandra-Nadia Ngwabyt

  • The Gli code: an information nexus regulating cell fate, stemness and cancer

    Ariel Ruiz i Altaba;Christophe Mas;Barbara Stecca

  • Gli proteins and Hedgehog signaling: development and cancer.

    Ariel Ruiz i Altaba

  • Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex

    Verónica Palma;Ariel Ruiz i Altaba

  • Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals

    Barbara Stecca;Ariel Ruiz i Altaba

  • A GLI1‐p53 inhibitory loop controls neural stem cell and tumour cell numbers

    Barbara Stecca;Ariel Ruiz i Altaba

  • Catching a Gli-mpse of Hedgehog

    Ariel Ruiz i Altaba

  • Wnt signals are targets and mediators of Gli function.

    Jose L. Mullor;Nadia Dahmane;Tao Sun;Ariel Ruiz i Altaba

  • Pathways and consequences: Hedgehog signaling in human disease

    José L Mullor;Pilar Sánchez;Ariel Ruiz i Altaba

Frequent Co-Authors

Howard L. Weiner
Howard L. Weiner Harvard University
Arturo Alvarez-Buylla
Arturo Alvarez-Buylla University of California, San Francisco
Alain Prochiantz
Alain Prochiantz Collège de France
Alan Carleton
Alan Carleton University of Geneva
Maximilian Muenke
Maximilian Muenke American College of Medical Genetics
Marie-Laure Yaspo
Marie-Laure Yaspo Max Planck Society
Bernhard G. Herrmann
Bernhard G. Herrmann Max Planck Society
Erich Roessler
Erich Roessler National Institutes of Health
Gabriele Gillessen-Kaesbach
Gabriele Gillessen-Kaesbach University of Lübeck
Hans Lehrach
Hans Lehrach Max Planck Society

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