Roberto Manetti

Overview

Best Publications

• Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

  R Manetti;P Parronchi;M G Giudizi;M P Piccinni

  2056
  Citations

• Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

  M Pizza;[No Value] Scarlato;[No Value] Masignani;MM Giuliani

  1672
  Citations

• Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones.

  M P Piccinni;M G Giudizi;R Biagiotti;L Beloni

  1048
  Citations

• Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones.

  E Maggi;P Parronchi;R Manetti;C Simonelli

  885
  Citations

• Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones.

  R Manetti;F Gerosa;M G Giudizi;R Biagiotti

  623
  Citations

• Ability of HIV to promote a TH1 to TH0 shift and to replicate preferentially in TH2 and TH0 cells

  Enrico Maggi;Marcello Mazzetti;Adriana Ravina;Francesco Annunziato

  609
  Citations

• IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones.

  P Parronchi;M De Carli;R Manetti;C Simonelli

  548
  Citations

• Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes.

  Francesco Annunziato;Lorenzo Cosmi;Francesco Liotta;Elena Lazzeri

  544
  Citations

• Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

  Lorenzo Cosmi;Francesco Liotta;Elena Lazzeri;Michela Francalanci

  537
  Citations

• Mutants of pertussis toxin suitable for vaccine development

  Mariagrazia Pizza;Antonio Covacci;Antonella Bartoloni;Maria Perugini

  429
  Citations

• Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection.

  Enrico Maggi;Maria Grazia Giudizi;Roberta Biagiotti;Francesco Annunziato

  384
  Citations

• CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease.

  Lorenzo Cosmi;Francesco Annunziato;Masahiro Iwasaki;Grazia Galli

  379
  Citations

• Active tuberculosis in Africa is associated with reduced Th1 and increased Th2 activity in vivo

  Christian Lienhardt;Annalisa Azzurri;Amedeo Amedei;Katherine Fielding

  322
  Citations

• Low pH Activates the Vacuolating Toxin of Helicobacter pylori, Which Becomes Acid and Pepsin Resistant

  Marina de Bernard;Emanuele Papini;Vincenzo de Filippis;Elena Gottardi

  280
  Citations

• The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin

  Emanuele Papini;Barbara Satin;Cecilia Bucci;Marina de Bernard

  272
  Citations

• Genomic Approach for Analysis of Surface Proteins in Chlamydia pneumoniae

  Silvia Montigiani;Fabiana Falugi;Maria Scarselli;Oretta Finco

  270
  Citations

• Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant

  Marta Marchetti;Michela Rossi;Valentina Giannelli;Marzia M. Giuliani

  266
  Citations

• Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo.

  Francesco Annunziato;Lorenzo Cosmi;Grazia Galli;Chiara Beltrame

  265
  Citations

• Aeroallergen Sensitization Can Occur during Fetal Life

  Piccinni Mp;Mecacci F;Sampognaro S;Manetti R

  226
  Citations

• Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines.

  Lorenzo Cosmi;Francesco Liotta;Roberta Angeli;Benedetta Mazzinghi

  221
  Citations