World's Best Scientists 2026 revealed!
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Medicine
Switzerland
2023

D-Index & Metrics

Immunology

D-Index
103
Citations
31460
World Ranking
653
National Ranking
59

Medicine

D-Index
103
Citations
31461
World Ranking
7450
National Ranking
727

Research.com Recognitions

  • 2023 - Research.com Medicine in Switzerland Leader Award

Overview

Derek O'hagan is affiliated with GlaxoSmithKline in the United Kingdom and has a research focus primarily in the fields of Medicine and Immunology and Microbiology. Their work extensively covers subfields such as Immunology, Infectious Diseases, and Molecular Biology.

The scientist's main topics of research include Immunotherapy and Immune Responses, SARS-CoV-2 and COVID-19 Research, Immune Response and Inflammation, Animal Virus Infections Studies, RNA Interference and Gene Delivery, Viral Infections and Immunology Research, and vaccines and immunoinformatics approaches.

O'hagan has published several recent papers in notable scientific journals, including:

  • Emerging concepts in the science of vaccine adjuvants, 2021, Nature Reviews Drug Discovery
  • Adjuvanting a subunit COVID-19 vaccine to induce protective immunity, 2021, Nature
  • Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines, 2021, Cell
  • Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection, 2020, Journal of Controlled Release
  • Lipid-Based Nanoparticles for Delivery of Vaccine Adjuvants and Antigens: Toward Multicomponent Vaccines, 2021, Molecular Pharmaceutics

Frequent coauthors collaborating with O'hagan include Bali Pulendran, Prabhu S. Arunachalam, Harry Kleanthous, Robbert van der Most, and François Villinger.

The scientist's publications appear regularly in the following venues:

  • npj Vaccines
  • Journal of Controlled Release
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Pharmaceutics
  • Vaccines

Best Publications

  • Emerging concepts in the science of vaccine adjuvants.

    Bali Pulendran;Prabhu S. Arunachalam;Derek T. O’Hagan

  • Nonviral delivery of self-amplifying RNA vaccines

    Andrew J. Geall;Ayush Verma;Gillis R. Otten;Christine A. Shaw

  • Advances in vaccine adjuvants.

    Manmohan Singh;Derek O'Hagan

  • Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

    Fiona A Sharp;Darren Thomas Ruane;Benjamin Claass;Emma Creagh

  • Cationic microparticles: A potent delivery system for DNA vaccines

    Manmohan Singh;Maylene Briones;Gary Ott;Derek O'Hagan

  • Molecular and cellular signatures of human vaccine adjuvants

    F. Mosca;E. Tritto;A. Muzzi;E. Monaci

  • Recent advances in the discovery and delivery of vaccine adjuvants.

    Derek T. O'Hagan;Nicholas M. Valiante

  • The Adjuvants Aluminum Hydroxide and MF59 Induce Monocyte and Granulocyte Chemoattractants and Enhance Monocyte Differentiation toward Dendritic Cells

    Anja Seubert;Elisabetta Monaci;Mariagrazia Pizza;Derek T. O’Hagan

  • The mechanism of action of MF59 - an innately attractive adjuvant formulation.

    D.T. O’Hagan;G.S. Ott;E. De Gregorio;A. Seubert

  • Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes.

    Samuele Calabro;Marco Tortoli;Barbara C. Baudner;Alessandra Pacitto

  • Recent developments in adjuvants for vaccines against infectious diseases.

    Derek T. O'Hagan;Mary Lee MacKichan;Manmohan Singh

  • Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want.

    Harm HogenEsch;Derek T. O’Hagan;Christopher B. Fox

  • Biodegradable microparticles as controlled release antigen delivery systems.

    D T O'Hagan;D Rahman;J P McGee;H Jeffery

  • The history of MF59® adjuvant: a phoenix that arose from the ashes

    Derek T O'Hagan;Gary S Ott;Gary Van Nest;Rino Rappuoli

  • Recent advances in vaccine adjuvants.

    Manmohan Singh;Derek T. O'Hagan

  • A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines

    Luis A Brito;Michelle Chan;Christine A Shaw;Armin Hekele

  • The path to a successful vaccine adjuvant--'the long and winding road'.

    Derek T. O’Hagan;Ennio De Gregorio

  • Nanoparticles and microparticles as vaccine-delivery systems.

    Manmohan Singh;Aravind Chakrapani;Derek O'Hagan

  • Poly(lactide-co-glycolide) microparticles for the development of single-dose controlled-release vaccines.

    Derek T O'Hagan;Manmohan Singh;Rajesh K Gupta

  • Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.

    Prabhu S. Arunachalam;Alexandra C. Walls;Nadia Golden;Caroline Atyeo

  • MF59 is a safe and potent vaccine adjuvant that enhances protection against influenza virus infection

    Derek T O'Hagan

Frequent Co-Authors

John J. Donnelly
John J. Donnelly Novartis (United States)
Susan W. Barnett
Susan W. Barnett Bill & Melinda Gates Foundation
Jeffrey B. Ulmer
Jeffrey B. Ulmer Novartis (Switzerland)
Rino Rappuoli
Rino Rappuoli Imperial College London
Nicholas M. Valiante
Nicholas M. Valiante Novartis (Switzerland)
Ed C. Lavelle
Ed C. Lavelle Trinity College Dublin
Ennio De Gregorio
Ennio De Gregorio Novartis (Switzerland)
Andreas Wack
Andreas Wack The Francis Crick Institute
Wayne C. Koff
Wayne C. Koff International AIDS Vaccine Initiative
Philip R. Dormitzer
Philip R. Dormitzer Pfizer (United States)

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