The scientist’s investigation covers issues in Immunology, Immune system, Adjuvant, Antigen and Virology. His research brings together the fields of Microparticle and Immune system. His Adjuvant research integrates issues from MF59, Influenza vaccine, Immunogenicity, Vaccination and Microbiology.
His Immunogenicity research is multidisciplinary, incorporating perspectives in Immunoglobulin G, Immunization and Small interfering RNA. His Antigen study combines topics from a wide range of disciplines, such as Oral administration, Gastrointestinal tract and Drug carrier. His studies in Virology integrate themes in fields like Mucosal immunology and Viral vector.
His main research concerns Immunology, Adjuvant, Antigen, Immune system and Virology. His work on Immunology deals in particular with Immunization, Antibody, Immunity, Nasal administration and Immunoglobulin G. His research in Adjuvant focuses on subjects like Squalene, which are connected to Emulsion.
His study in Antigen is interdisciplinary in nature, drawing from both Molecular biology, Biochemistry, Microbiology and Microparticle. His study focuses on the intersection of Immune system and fields such as In vivo with connections in the field of In vitro. His work focuses on many connections between Virology and other disciplines, such as DNA vaccination, that overlap with his field of interest in Naked DNA.
His primary areas of study are Adjuvant, Immune system, Antigen, Immunology and Immunogenicity. He combines subjects such as Squalene, MF59, Antibody and Pharmacology with his study of Adjuvant. In general Immune system, his work in Immunity is often linked to Antibody titer linking many areas of study.
His Antigen study integrates concerns from other disciplines, such as Virology, Agonist, Potentiator, Hydroxide and Combinatorial chemistry. His work in the fields of Immunology, such as Immunization, Adjuvanticity, Innate immune system and Reactogenicity, intersects with other areas such as Delivery system. His work deals with themes such as Glycoconjugate, Biochemistry, Toll-like receptor and Antigen-presenting cell, which intersect with Immunogenicity.
His scientific interests lie mostly in Immunology, Adjuvant, Immune system, Antigen and Virology. His work in the fields of Innate immune system overlaps with other areas such as Delivery system. Derek T. O'Hagan works mostly in the field of Adjuvant, limiting it down to concerns involving MF59 and, occasionally, Viral vector, Nucleic acid and Clinical trial.
His research in Immune system intersects with topics in In vivo and Potentiator. His study in the field of Vaccine adjuvant also crosses realms of Antibody titer. Derek T. O'Hagan interconnects Antibody and Immunization in the investigation of issues within Virology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Cationic microparticles: A potent delivery system for DNA vaccines
Manmohan Singh;Maylene Briones;Gary Ott;Derek O'Hagan.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Advances in vaccine adjuvants.
Manmohan Singh;Derek O'Hagan.
Nature Biotechnology (1999)
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Fiona A Sharp;Darren Thomas Ruane;Benjamin Claass;Emma Creagh.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Recent advances in the discovery and delivery of vaccine adjuvants.
Derek T. O'Hagan;Nicholas M. Valiante.
Nature Reviews Drug Discovery (2003)
Molecular and cellular signatures of human vaccine adjuvants
F. Mosca;E. Tritto;A. Muzzi;E. Monaci.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Recent developments in adjuvants for vaccines against infectious diseases.
Derek T. O'Hagan;Mary Lee MacKichan;Manmohan Singh.
Biomolecular Engineering (2001)
The Adjuvants Aluminum Hydroxide and MF59 Induce Monocyte and Granulocyte Chemoattractants and Enhance Monocyte Differentiation toward Dendritic Cells
Anja Seubert;Elisabetta Monaci;Mariagrazia Pizza;Derek T. O’Hagan.
Journal of Immunology (2008)
Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes.
Samuele Calabro;Marco Tortoli;Barbara C. Baudner;Alessandra Pacitto.
Vaccine (2011)
Recent advances in vaccine adjuvants.
Manmohan Singh;Derek T. O'Hagan.
Pharmaceutical Research (2002)
The mechanism of action of MF59 - an innately attractive adjuvant formulation.
D.T. O’Hagan;G.S. Ott;E. De Gregorio;A. Seubert.
Vaccine (2012)
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