His primary areas of study are Immune system, Immunology, Cell biology, Inflammasome and Innate immune system. His Immune system research integrates issues from Interleukin 18, Signal transduction and Microbiology. Immunology is closely attributed to Bordetella pertussis in his research.
His biological study spans a wide range of topics, including Proinflammatory cytokine and Cytokine. His research in Inflammasome tackles topics such as Secretion which are related to areas like Autophagy and Cellular immunity. His Innate immune system study frequently draws connections to other fields, such as Antigen.
Ed C. Lavelle focuses on Immunology, Immune system, Antigen, Adjuvant and Innate immune system. His Vaccination, Immunity, Cytokine, Acquired immune system and Immunogenicity investigations are all subjects of Immunology research. His research in Cytokine intersects with topics in Inflammation, Proinflammatory cytokine, Secretion and Cell biology.
His Immune system research includes elements of Lectin, Inflammasome, Antibody and Microbiology. His Antigen research focuses on T cell and how it relates to Interleukin 17 and Autoimmunity. His Adjuvant research incorporates elements of Alum, Pharmacology and Virology.
His main research concerns Immunology, Immune system, Cell biology, Inflammation and Innate immune system. His Immunology research includes themes of Disease and Pneumonia. His research in Immune system intersects with topics in Adjuvant and Antigen.
His Innate immune system research is multidisciplinary, incorporating perspectives in Proinflammatory cytokine, Neurodegeneration, Cytokine and Antigen-presenting cell. His Cytokine research incorporates themes from T cell, Secretion and Effector. The various areas that he examines in his Acquired immune system study include Inflammasome and Pharmacology.
The scientist’s investigation covers issues in Immunology, Immune system, Inflammation, Cytokine and Innate immune system. His biological study focuses on Immunity. His Immune system study integrates concerns from other disciplines, such as Adjuvant and Vaccination.
His Inflammation research is multidisciplinary, incorporating elements of Neurodegeneration and Stimulator of interferon genes. His research investigates the connection with Cytokine and areas like Cell biology which intersect with concerns in Interleukin 33 and Macrophage. His biological study spans a wide range of topics, including Acquired immune system, Inflammasome and Adjuvanticity.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity
Caroline E. Sutton;Stephen J. Lalor;Cheryl M. Sweeney;Corinna F. Brereton.
Immunity (2009)
A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
Caroline Sutton;Corinna Brereton;Brian Keogh;Kingston H.G. Mills.
Journal of Experimental Medicine (2006)
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
Seth L Masters;Aisling Dunne;Shoba L Subramanian;Rebecca L Hull.
Nature Immunology (2010)
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
James Harris;Michelle L Hartman;Caitrionna Jane Roche;Shijuan Grace Zeng.
Journal of Biological Chemistry (2011)
Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases
Alexander U. Lüthi;Sean P. Cullen;Edel A. McNeela;Patrick J. Duriez.
Immunity (2009)
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Fiona A Sharp;Darren Thomas Ruane;Benjamin Claass;Emma Creagh.
Proceedings of the National Academy of Sciences of the United States of America (2009)
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Sarah C. Higgins;Andrew G. Jarnicki;Ed C. Lavelle;Kingston H. G. Mills.
Journal of Immunology (2006)
Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4
Edel A. McNeela;Áine Burke;Daniel R. Neill;Cathy Baxter.
PLOS Pathogens (2010)
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
Sarah L. Doyle;Matthew Campbell;Ema Ozaki;Robert G. Salomon.
Nature Medicine (2012)
Toll-Like Receptor 4-Mediated Innate IL-10 Activates Antigen-Specific Regulatory T Cells and Confers Resistance to Bordetella pertussis by Inhibiting Inflammatory Pathology
Sarah C. Higgins;Ed C. Lavelle;Chantelle McCann;Brian Keogh.
Journal of Immunology (2003)
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