World's Best Scientists 2026 revealed!
Seamus J. Martin

Seamus J. Martin

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Biology and Biochemistry
Ireland
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
101
Citations
78470
World Ranking
1403
National Ranking
5

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2025 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2006 - Member of the Royal Irish Academy
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Seamus J. Martin is affiliated with Trinity College Dublin in Ireland and has contributed significantly to the field of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology and Immunology. Their research interests span multiple subfields, including Cancer Research, Public Health, Environmental and Occupational Health, and Physiology.

The primary topics covered in their work include cell death mechanisms and regulation, interferon and immune responses, and the IL-33, ST2, and ILC pathways. Other areas of research involve neutrophil, myeloperoxidase, and oxidative mechanisms, health, environment, cognitive aging, and extracellular vesicles in disease.

The scientist has published extensively, with a total of 33 publications in their main field. Frequent publication venues include the FEBS Journal with 27 papers, Cell Reports with 3, bioRxiv (Cold Spring Harbor Laboratory) with 2, Faculty of 1000 Research Ltd with 2, and Current Protocols with 1.

Recent papers include:

  • Discriminating Between Apoptosis, Necrosis, Necroptosis, and Ferroptosis by Microscopy and Flow Cytometry, 2023, Current Protocols
  • TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation, 2020, Developmental Cell
  • cFLIPL acts as a suppressor of TRAIL- and Fas-initiated inflammation by inhibiting assembly of caspase-8/FADD/RIPK1 NF-κB-activating complexes, 2023, Cell Reports
  • TRAIL signaling promotes entosis in colorectal cancer, 2021, The Journal of Cell Biology
  • IL-1 family cytokines serve as 'activity recognition receptors' for aberrant protease activity indicative of danger, 2022, Cytokine

Seamus J. Martin has collaborated with multiple frequent co-authors, including Daniel B. Longley, Dublin Chair, Andrey Abramov, Colin Adrain, and Cecília M. Arraiano. These collaborations indicate involvement in a broad network of research efforts.

Awards received by the scientist include membership of the Royal Irish Academy in 2006 and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

    S. J. Martin;C. P. M. Reutelingsperger;A. J. Mcgahon;J. A. Rader

  • Apoptosis: controlled demolition at the cellular level

    Rebecca C. Taylor;Sean P. Cullen;Seamus J. Martin

  • Suppression of TNF-α-Induced Apoptosis by NF-κB

    Daniel J. Van Antwerp;Seamus J. Martin;Tal Kafri;Douglas R. Green

  • Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.

    Elizabeth A. Slee;Mary T. Harte;Ruth M. Kluck;Beni B. Wolf

  • Protease activation during apoptosis: Death by a thousand cuts?

    Seamus J Martin;Douglas R Green

  • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

    Thomas Brunner;Rona J. Mogil;Drake LaFace;Nam Jin Yoo

  • Executioner Caspase-3, -6, and -7 Perform Distinct, Non-redundant Roles during the Demolition Phase of Apoptosis *

    Elizabeth A. Slee;Colin Adrain;Seamus J. Martin

  • Autophagy in malignant transformation and cancer progression

    Lorenzo Galluzzi;Federico Pietrocola;Federico Pietrocola;José Manuel Bravo-San Pedro;José Manuel Bravo-San Pedro;Ravi K. Amaravadi

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli

    S. V. Lennon;S. J. Martin;T. G. Cotter

  • Acid Sphingomyelinase–Deficient Human Lymphoblasts and Mice Are Defective in Radiation-Induced Apoptosis

    Pino Santana;Louis A Peña;Adriana Haimovitz-Friedman;Seamus Martin

  • Caspase-independent cell death.

    Guido Kroemer;Seamus J Martin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

    G van Loo;X Saelens;M van Gurp;M MacFarlane

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

    Alexander U. Lüthi;Sean P. Cullen;Edel A. McNeela;Patrick J. Duriez

  • The mitochondrial apoptosome: a killer unleashed by the cytochrome seas.

    Colin Adrain;Seamus J Martin

Frequent Co-Authors

Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital
Thomas G. Cotter
Thomas G. Cotter University College Cork
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Peter Vandenabeele
Peter Vandenabeele Ghent University
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Guido Kroemer
Guido Kroemer Université Paris Cité
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Hans-Uwe Simon
Hans-Uwe Simon University of Bern

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