D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 12,093 197 World Ranking 9341 National Ranking 676

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Gene
  • Mutation

His primary scientific interests are in Cancer, Germline mutation, Genetics, Noonan syndrome and Pathology. Cancer is a subfield of Internal medicine that Christian P. Kratz investigates. His biological study spans a wide range of topics, including Medulloblastoma and Li–Fraumeni syndrome.

The Germline mutation study combines topics in areas such as Immunology, Malignancy, Pediatrics and Lynch syndrome. His Noonan syndrome research is multidisciplinary, incorporating elements of KRAS, Costello syndrome, PTPN11 and Ectodermal dysplasia. The concepts of his Pathology study are interwoven with issues in Congenital Neutropenia, HAX1, Genetic linkage, Leukemia and Candidate gene.

His most cited work include:

  • The landscape of genomic alterations across childhood cancers (449 citations)
  • Comprehensive Analysis of Hypermutation in Human Cancer (319 citations)
  • A Syndrome with Congenital Neutropenia and Mutations in G6PC3 (257 citations)

What are the main themes of his work throughout his whole career to date?

Christian P. Kratz focuses on Internal medicine, Oncology, Cancer, Genetics and Immunology. His Internal medicine study integrates concerns from other disciplines, such as Bone marrow failure and Li–Fraumeni syndrome. As part of the same scientific family, Christian P. Kratz usually focuses on Oncology, concentrating on Genotype and intersecting with Young adult.

The study incorporates disciplines such as Genetic counseling, Epidemiology and Human genetics in addition to Cancer. His Leukemia study in the realm of Immunology connects with subjects such as In patient. His Germline mutation study incorporates themes from Pathology, MSH2, DNA mismatch repair and Microsatellite instability.

He most often published in these fields:

  • Internal medicine (36.59%)
  • Oncology (26.83%)
  • Cancer (22.76%)

What were the highlights of his more recent work (between 2018-2021)?

  • Internal medicine (36.59%)
  • Cancer (22.76%)
  • Oncology (26.83%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Internal medicine, Cancer, Oncology, Genetic counseling and Germline mutation. His Internal medicine study frequently intersects with other fields, such as Genotype. His studies deal with areas such as Epidemiology, Host genome and Intensive care medicine as well as Cancer.

His Oncology research includes themes of Childhood Cancer Registry, Li–Fraumeni syndrome, Germline and Ovarian Teratoma, Ovary. To a larger extent, Christian P. Kratz studies Genetics with the aim of understanding Genetic counseling. His research in Germline mutation intersects with topics in Hemophagocytic lymphohistiocytosis, Hematopoietic stem cell transplantation, Microsatellite instability and DNA mismatch repair.

Between 2018 and 2021, his most popular works were:

  • Neoplasm Risk Among Individuals With a Pathogenic Germline Variant in DICER1. (35 citations)
  • Understanding the evolving phenotype of vascular complications in telomere biology disorders (23 citations)
  • MYCN amplification drives an aggressive form of spinal ependymoma. (21 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Gene
  • Mutation

Christian P. Kratz mainly focuses on Internal medicine, Oncology, Germline mutation, Genotype and Cancer. His Oncology study combines topics from a wide range of disciplines, such as Germ cell tumors, Stage and Ovarian Teratoma, Ovary. His Germline mutation research integrates issues from Differential diagnosis, Pediatrics, Germline and Medical genetics.

In his study, Microsatellite, DNA mismatch repair, Microsatellite instability and Lynch syndrome is inextricably linked to DNA sequencing, which falls within the broad field of Germline. His work carried out in the field of Genotype brings together such families of science as Hepatoblastoma, Observational study, Retrospective cohort study and Childhood Cancer Registry. Christian P. Kratz has included themes like Phenotype, Telomere biology and Cohort in his Cancer study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The landscape of genomic alterations across childhood cancers

Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter.
Nature (2018)

840 Citations

Germline KRAS mutations cause Noonan syndrome

Suzanne Schubbert;Martin Zenker;Sara L . Rowe;Silke Böll.
Nature Genetics (2006)

800 Citations

Detectable clonal mosaicism and its relationship to aging and cancer

Kevin B. Jacobs;Kevin B. Jacobs;Meredith Yeager;Meredith Yeager;Weiyin Zhou;Weiyin Zhou;Sholom Wacholder.
Nature Genetics (2012)

564 Citations

Comprehensive Analysis of Hypermutation in Human Cancer

Brittany B. Campbell;Nicholas Light;David Fabrizio;Matthew Zatzman.
Cell (2017)

553 Citations

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

Stefan Pfister;Wibke G. Janzarik;Marc Remke;Aurélie Ernst.
Journal of Clinical Investigation (2008)

519 Citations

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

Christian P. Kratz;Maria Isabel Achatz;Laurence Brugieres;Thierry Frebourg.
Clinical Cancer Research (2017)

345 Citations

A Syndrome with Congenital Neutropenia and Mutations in G6PC3

Kaan Boztug;Giridharan Appaswamy;Angel Ashikov;Alejandro A. Schäffer.
The New England Journal of Medicine (2009)

340 Citations

Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium ‘Care for CMMRD’ (C4CMMRD)

Katharina Wimmer;Christian P Kratz;Hans F A Vasen;Olivier Caron.
Journal of Medical Genetics (2014)

339 Citations

A restricted spectrum of NRAS mutations causes Noonan syndrome

Ion C. Cirstea;Kerstin Kutsche;Radovan Dvorsky;Lothar Gremer.
Nature Genetics (2010)

328 Citations

The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease

Christian P. Kratz;Charlotte M. Niemeyer;Robert P. Castleberry;Mualla Cetin.
Blood (2005)

287 Citations

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