Paul F. Kenna

Overview

Best Publications

• Retinopathy induced in mice by targeted disruption of the rhodopsin gene

  Humphries Mm;Rancourt D;Farrar Gj;Kenna P;Kenna P

  637
  Citations

• A three-base-pair deletion in the peripherin– RDS gene in one form of retinitis pigmentosa

  Farrar Gj;Kenna P;Jordan Sa;Kumar-Singh R

  505
  Citations

• NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

  Sarah L. Doyle;Matthew Campbell;Ema Ozaki;Robert G. Salomon

  481
  Citations

• Autosomal dominant retinitis pigmentosa (ADRP): Localization of an ADRP gene to the long arm of chromosome 3

  Peter McWilliam;G.Jane Farrar;Paul Kenna;Daniel G. Bradley

  306
  Citations

• On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

  G. Jane Farrar;Paul F. Kenna;Peter Humphries

  294
  Citations

• On the molecular genetics of retinitis pigmentosa

  P Humphries;P Kenna;GJ Farrar

  262
  Citations

• Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia

  C Greene;J Kealy;M M Humphries;Y Gong

  242
  Citations

• Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho-/- mice.

  Avril Kennan;Aileen Aherne;Arpad Palfi;Marian Humphries

  231
  Citations

• RNA interference-mediated suppression and replacement of human rhodopsin in vivo.

  Mary O’Reilly;Arpad Palfi;Naomi Chadderton;Sophia Millington-Ward

  217
  Citations

• Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice.

  Udo Bartsch;Wasi Oriyakhel;Paul F. Kenna;Stephan Linke

  195
  Citations

• Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa.

  Carol J Loscher;Karsten Hokamp;Paul F Kenna;Alasdair C Ivens

  178
  Citations

• Improved retinal function in a mouse model of dominant retinitis pigmentosa following AAV-delivered gene therapy.

  Naomi Chadderton;Sophia Millington-Ward;Arpad Palfi;Mary O'Reilly

  173
  Citations

• Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa

  Sophia Millington-Ward;Naomi Chadderton;Mary O'Reilly;Arpad Palfi

  172
  Citations

• A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement

  Sara J. Bowne;Marian M. Humphries;Lori S. Sullivan;Paul F. Kenna;Paul F. Kenna

  165
  Citations

• Localization of an autosomal dominant retinitis pigmentosa gene to chromosome 7q

  S A Jordan;G J Farrar;P Kenna;M M Humphries

  155
  Citations

• Autosomal dominant retinitis pigmentosa: linkage to rhodopsin and evidence for genetic heterogeneity

  G. Jane Farrar;Peter McWilliam;Daniel G. Bradley;Paul Kenna

  145
  Citations

• Retinitis Pigmentosa and Progressive Sensorineural Hearing Loss Caused by a C12258A Mutation in the Mitochondrial MTTS2 Gene

  Fiona C. Mansergh;Sophia Millington-Ward;Avril Kennan;Anna-Sophia Kiang

  144
  Citations

• Ocular findings associated with a rhodopsin gene codon 58 transversion mutation in autosomal dominant retinitis pigmentosa.

  Gerald A. Fishman;Edwin M. Stone;Leonardo D. Gilbert;Paul Kenna

  137
  Citations

• A NOVEL MUTATION WITHIN THE RHODOPSIN GENE (THR-94-ILE) CAUSING AUTOSOMAL DOMINANT CONGENITAL STATIONARY NIGHT BLINDNESS

  Najma al-Jandal;G. Jane Farrar;Anna-Sophia Kiang;Marian M. Humphries

  127
  Citations

• IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration.

  Sarah L. Doyle;Ema Ozaki;Kiva Brennan;Marian M. Humphries

  124
  Citations