What is he best known for?
The fields of study he is best known for:
Alan Eastman mostly deals with Apoptosis, Molecular biology, Cell cycle, Programmed cell death and Biochemistry.
His Apoptosis study integrates concerns from other disciplines, such as Intracellular pH, Intracellular and Chinese hamster ovary cell.
His studies deal with areas such as In vitro, DNA repair, Okadaic acid, DUSP6 and Protein phosphatase 1 as well as Molecular biology.
His studies in Cell cycle integrate themes in fields like Mitosis, DNA damage and DNA synthesis.
His Programmed cell death research incorporates themes from Deoxyribonuclease II, Acetylation, Extracellular, Cell biology and Endonuclease.
The study incorporates disciplines such as Cancer research and Topoisomerase-I Inhibitor in addition to Cell cycle checkpoint.
His most cited work include:
- Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. (788 citations)
- UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p53 (423 citations)
- Identification of deoxyribonuclease II as an endonuclease involved in apoptosis (389 citations)
What are the main themes of his work throughout his whole career to date?
Alan Eastman focuses on Apoptosis, Cancer research, Molecular biology, Cell biology and DNA damage.
His Apoptosis course of study focuses on Pharmacology and In vivo.
His Cancer research study combines topics in areas such as Cancer, Cell cycle, Cisplatin, Immunology and Chronic lymphocytic leukemia.
His research integrates issues of Mitosis and DNA synthesis in his study of Cell cycle.
His Molecular biology study incorporates themes from Cell culture, Chinese hamster ovary cell and Deoxyribonuclease II, Biochemistry, DNA.
The concepts of his DNA damage study are interwoven with issues in CHEK1, Cell cycle checkpoint, DNA repair, Regulator and Topoisomerase-I Inhibitor.
He most often published in these fields:
- Apoptosis (29.78%)
- Cancer research (29.78%)
- Molecular biology (27.53%)
What were the highlights of his more recent work (between 2011-2021)?
- Cancer research (29.78%)
- DNA damage (21.35%)
- Pharmacology (9.55%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cancer research, DNA damage, Pharmacology, Apoptosis and Chronic lymphocytic leukemia.
Alan Eastman interconnects Cancer, Cell cycle, Gemcitabine, Immunology and DNA repair in the investigation of issues within Cancer research.
His study brings together the fields of Mitosis and Cell cycle.
His work carried out in the field of DNA damage brings together such families of science as CHEK1, Cell cycle checkpoint, Cell killing, Cell biology and Topoisomerase-I Inhibitor.
The various areas that Alan Eastman examines in his CHEK1 study include G2-M DNA damage checkpoint, Molecular biology and DNA replication.
His Apoptosis research includes elements of In vitro, Signal transduction, Kinase and MCL1.
Between 2011 and 2021, his most popular works were:
- Microtubule destabilising agents: far more than just antimitotic anticancer drugs. (109 citations)
- Preclinical Development of the Novel Chk1 Inhibitor SCH900776 in Combination with DNA-Damaging Agents and Antimetabolites (106 citations)
- The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies impact on clinical trial design. (93 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Pharmacology, Cancer research, Apoptosis, DNA damage and Chronic lymphocytic leukemia.
Alan Eastman studied Cancer research and Cell cycle that intersect with Mitosis.
Alan Eastman combines subjects such as In vitro and Estrogen receptor, Fulvestrant with his study of Apoptosis.
The DNA damage study combines topics in areas such as CHEK1, Cell cycle checkpoint, MRE11 Homologue Protein and Molecular biology.
His study in Chronic lymphocytic leukemia is interdisciplinary in nature, drawing from both Signal transduction and MCL1.
His research investigates the connection between In vivo and topics such as Cell that intersect with issues in Cell culture.
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