World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
9559
World Ranking
17595
National Ranking
7218

Overview

Christine M. Sorenson is affiliated with the University of Wisconsin-Madison in the United States and has made contributions primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research focuses extensively on ophthalmology, molecular biology, and related biomedical disciplines.

Their main areas of study include:

  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Angiogenesis and VEGF in Cancer
  • Retinopathy of Prematurity Studies
  • Retinal Imaging and Analysis
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Ocular Diseases and Behçet's Syndrome

The scientist has published a number of recent papers covering diverse topics related to vascular biology, ocular health, and diabetic conditions, including:

  • "Myeloid-Derived TSP1 (Thrombospondin-1) Contributes to Abdominal Aortic Aneurysm Through Suppressing Tissue Inhibitor of Metalloproteinases-1" (2020), published in Arteriosclerosis Thrombosis and Vascular Biology
  • "Cytochrome P450 1B1: A Key Regulator of Ocular Iron Homeostasis and Oxidative Stress" (2022), published in Cells
  • "Thrombospondin-1 in vascular development, vascular function, and vascular disease" (2023), published in Seminars in Cell and Developmental Biology
  • "Retinal inflammation in murine models of type 1 and type 2 diabetes with diabetic retinopathy" (2023), published in Diabetologia
  • "Noninvasive temporal detection of early retinal vascular changes during diabetes" (2020), published in Scientific Reports

Christine M. Sorenson frequently collaborates with several coauthors, which have contributed to a substantial body of research:

  • Nader Sheibani
  • Yong-Seok Song
  • Shoujian Wang
  • Soesiawati R. Darjatmoko
  • Ismail Zaitoun

Their publications often appear in notable scientific journals, reflecting consistency in particular research domains. Frequent publication venues include:

  • Cells
  • PLoS ONE
  • International Journal of Molecular Sciences
  • Experimental Eye Research
  • Frontiers in Cell and Developmental Biology

The scientist's work spans subfields such as ophthalmology, molecular biology, radiology, nuclear medicine and imaging, neurology, and pediatrics, perinatology, and child health. This interdisciplinary approach supports comprehensive research on eye diseases, vascular function, and related molecular mechanisms.

Best Publications

  • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

    Deborah J. Veis;Christine M. Sorenson;John R. Shutter;Stanley J. Korsmeyer

  • Analysis of Events Associated With Cell Cycle Arrest at G2 Phase and Cell Death Induced by Cisplatin

    Christine M. Sorenson;Michael A. Barry;Alan Eastman

  • Diabetes and retinal vascular dysfunction.

    Eui Seok Shin;Christine M Sorenson;Nader Sheibani

  • Isolation and characterization of murine retinal endothelial cells.

    Xiaojing Su;Christine M Sorenson;Nader Sheibani

  • Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation.

    Ji Yi;Wenzhong Liu;Siyu Chen;Vadim Backman

  • Bcl-2 family members and disease.

    Christine M. Sorenson

  • Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration.

    Shoujian Wang;Zhifeng Wu;Christine M. Sorenson;Jack Lawler

  • Functional role of inorganic trace elements in angiogenesis—Part II: Cr, Si, Zn, Cu, and S

    Mohammad Ali Saghiri;Armen Asatourian;Jafar Orangi;Christine M. Sorenson

  • Thrombospondin-1, a natural inhibitor of angiogenesis, is present in vitreous and aqueous humor and is modulated by hyperglycemia.

    Nader Sheibani;Christine M. Sorenson;Lynn A. Cornelius;William A. Frazier

  • CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression.

    Yixin Tang;Elizabeth A. Scheef;Shoujian Wang;Christine M. Sorenson

  • Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries.

    Anne S. Cuttler;Renée J. LeClair;J. Patrizia Stohn;Qiaozeng Wang

  • Thrombospondin-1 (TSP1) Contributes to the Development of Vascular Inflammation by Regulating Monocytic Cell Motility in Mouse Models of Abdominal Aortic Aneurysm

    Zhenjie Liu;Stephanie Morgan;Jun Ren;Qiwei Wang

  • Role of angiogenesis in endodontics: contributions of stem cells and proangiogenic and antiangiogenic factors to dental pulp regeneration

    Mohammad Ali Saghiri;Armen Asatourian;Christine M. Sorenson;Nader Sheibani

  • PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions.

    SunYoung Park;Terri A. DiMaio;Elizabeth A. Scheef;Christine M. Sorenson

  • PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis.

    Sunyoung Park;Christine M. Sorenson;Nader Sheibani

  • PEDF Deficient Mice Exhibit an Enhanced Rate of Retinal Vascular Expansion and Are More Sensitive to Hyperoxia-Mediated Vessel Obliteration

    Qiong Huang;Shoujian Wang;Christine M. Sorenson;Nader Sheibani

  • Attenuation of proliferation and migration of retinal pericytes in the absence of thrombospondin-1.

    Elizabeth A. Scheef;Christine M. Sorenson;Nader Sheibani

  • Functional role of inorganic trace elements in angiogenesis—Part I: N, Fe, Se, P, Au, and Ca

    Mohammad Ali Saghiri;Armen Asatourian;Jafar Orangi;Christine M. Sorenson

  • Electrochemical evidence for the molten globule states of cytochrome c induced by N-alkyl sulfates at low concentrations.

    A. A. Moosavi-Movahedi;J. Chamani;H. Ghourchian;H. Shafiey

  • Attenuation of retinal vascular development and neovascularization during oxygen-induced ischemic retinopathy in Bcl-2-/- mice.

    Shoujian Wang;Christine M. Sorenson;Nader Sheibani

Frequent Co-Authors

Nader Sheibani
Nader Sheibani University of Wisconsin–Madison
Colin R. Jefcoate
Colin R. Jefcoate University of Wisconsin–Madison
Jack Henkin
Jack Henkin Northwestern University
Ali Akbar Moosavi-Movahedi
Ali Akbar Moosavi-Movahedi University of Tehran
Kurt D. Hankenson
Kurt D. Hankenson University of Michigan–Ann Arbor
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Simon J. Conway
Simon J. Conway Indiana University
Lucy Liaw
Lucy Liaw Maine Medical Center
Michael A. Barry
Michael A. Barry Mayo Clinic
Louis F. Reichardt
Louis F. Reichardt University of California, San Francisco

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