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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
15981
World Ranking
10669
National Ranking
815

Overview

David Dinsdale is affiliated with the University of Leicester in the United Kingdom. Their work spans multiple fields within medicine, focusing on diverse areas such as epidemiology, molecular biology, immunology, neurology, and emergency medicine.

Their research covers several main topics, including:

  • Cell death mechanisms and regulation
  • Interferon and immune responses
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Traumatic Brain Injury Research
  • Trauma and Emergency Care Studies
  • PARP inhibition in cancer therapy
  • Autophagy in Disease and Therapy

Their recent publications reflect this range of interests and include:

  • Patient Outcomes at Twelve Months after Early Decompressive Craniectomy for Diffuse Traumatic Brain Injury in the Randomized DECRA Clinical Trial (2020), published in Journal of Neurotrauma
  • Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate (2021), published in Nature Communications
  • Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol (2021), published in Cell Death and Differentiation
  • Correction: p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis (2025), published in Oncogene

Frequent coauthors in their work include:

  • Kelvin Cain
  • Marion MacFarlane
  • D. James Cooper
  • Jeffrey V. Rosenfeld
  • Lynnette Murray

Their publications are spread across high-impact venues, specifically:

  • Journal of Neurotrauma
  • Nature Communications
  • Cell Death and Differentiation
  • Oncogene

Best Publications

  • Passage of inhaled particles into the blood circulation in humans.

    Abderrahim Nemmar;Peter Hoet;B Vanquickenborne;D Dinsdale

  • Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation.

    G M Cohen;X M Sun;R T Snowden;D Dinsdale

  • Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

    Cristian Bellodi;Maria Rosa Lidonnici;Ashley Hamilton;G. Vignir Helgason

  • Sustained translational repression by eIF2α-P mediates prion neurodegeneration

    Julie A. Moreno;Helois Radford;Diego Peretti;Joern R. Steinert

  • Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

    Meike Vogler;David Dinsdale;Martin J. S. Dyer;Gerald M. Cohen

  • Ultrafine particles affect experimental thrombosis in an in vivo hamster model.

    Abderrahim Nemmar;Marc F. Hoylaerts;Peter H. M. Hoet;David Dinsdale

  • Diesel Exhaust Particles in Lung Acutely Enhance Experimental Peripheral Thrombosis

    Abderrahim Nemmar;Peter H.M. Hoet;David Dinsdale;Jozef Vermylen

  • Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

    E Candi;A Rufini;A Terrinoni;D Dinsdale

  • Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

    G. M. Cohen;Xiao-Ming Sun;H. Fearnhead;M. Macfarlane

  • Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells

    Oliver Zaccheo;David Dinsdale;Peter A. Meacock;Paul Glynn

  • Different forms of cell death induced by putative BCL2 inhibitors.

    M Vogler;K Weber;D Dinsdale;I Schmitz

  • The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells

    S Galavotti;S Bartesaghi;D Faccenda;M Shaked-Rabi

  • RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration

    Diego Peretti;Amandine Bastide;Helois Radford;Nicholas Verity

  • Metabolic reprogramming during neuronal differentiation

    M Agostini;F Romeo;F Romeo;S Inoue;M V Niklison-Chirou

  • TAp63 and ΔNp63 in Cancer and Epidermal Development

    Eleanora Candi;David Dinsdale;Allesandro Rufini;Paolo Salomoni

  • HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

    Melania Capasso;Mandeep K Bhamrah;Tom Henley;Robert S Boyd

  • BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation.

    Meike Vogler;Hassan A. Hamali;Xiao-Ming Sun;Edward T. W. Bampton

  • Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis.

    Marion MacFarlane;Wendy Merrison;David Dinsdale;Gerald M. Cohen

  • Lung exposure to nanoparticles modulates an asthmatic response in a mouse model

    S Hussain;J A J Vanoirbeek;K Luyts;V De Vooght

  • Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells (vol 119, pg 1109, 2009)

    C Bellodi;Lidonnici;A Hamilton;GV Helgason

Frequent Co-Authors

Gerald M. Cohen
Gerald M. Cohen University of Liverpool
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Paolo Salomoni
Paolo Salomoni German Center for Neurodegenerative Diseases
Benoit Nemery
Benoit Nemery KU Leuven
Peter Hoet
Peter Hoet KU Leuven
Martin J. S. Dyer
Martin J. S. Dyer University of Leicester
Pierluigi Nicotera
Pierluigi Nicotera German Center for Neurodegenerative Diseases
Anne E. Willis
Anne E. Willis University of Cambridge
Marion MacFarlane
Marion MacFarlane University of Cambridge
Richard A. Knight
Richard A. Knight University College London

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