Marion MacFarlane

Overview

Best Publications

• Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

  Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  6452
  Citations

• Distinct Caspase Cascades Are Initiated in Receptor-mediated and Chemical-induced Apoptosis

  Xiao-Ming Sun;Marion MacFarlane;Jianguo Zhuang;Beni B. Wolf

  1232
  Citations

• cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

  Maria Feoktistova;Maria Feoktistova;Peter Geserick;Peter Geserick;Beate Kellert;Diana Panayotova Dimitrova

  1188
  Citations

• The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

  Tencho Tenev;Katiuscia Bianchi;Maurice Darding;Meike Broemer

  922
  Citations

• The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

  G van Loo;X Saelens;M van Gurp;M MacFarlane

  891
  Citations

• Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL

  Marion MacFarlane;Manzoor Ahmad;Srinivasa M. Srinivasula;Teresa Fernandes-Alnemri

  763
  Citations

• Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32.

  Elizabeth A. Slee;Huijun Zhu;Sek C. Chow;Marion MacFARLANE

  607
  Citations

• Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis.

  Shawn B. Bratton;Marion MacFarlane;Kelvin Cain;Gerald M. Cohen

  555
  Citations

• Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro.

  Marion MacFarlane;Wendy Merrison;Shawn B. Bratton;Gerald M. Cohen

  393
  Citations

• A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

  Laura S. Dickens;Robert S. Boyd;Rebekah Jukes-Jones;Michelle A. Hughes

  368
  Citations

• Pulmonary toxicity of carbon nanotubes and asbestos — Similarities and differences

  Ken Donaldson;Craig A. Poland;Fiona A. Murphy;Marion MacFarlane

  349
  Citations

• Different Subcellular Distribution of Caspase-3 and Caspase-7 following Fas-induced Apoptosis in Mouse Liver *

  Julia M. Chandler;Gerald M. Cohen;Marion MacFarlane

  336
  Citations

• TRAIL-induced signalling and apoptosis

  Marion MacFarlane

  321
  Citations

• Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

  G. M. Cohen;Xiao-Ming Sun;H. Fearnhead;M. Macfarlane

  306
  Citations

• c-Myc Protein Synthesis Is Initiated from the Internal Ribosome Entry Segment during Apoptosis

  Mark Stoneley;Stephen A. Chappell;Catherine L. Jopling;Martin Dickens

  296
  Citations

• Bcl-2 and Bcl-xL Inhibit CD95-mediated Apoptosis by Preventing Mitochondrial Release of Smac/DIABLO and Subsequent Inactivation of X-linked Inhibitor-of-Apoptosis Protein

  Xiao Ming Sun;Shawn B. Bratton;Michael Butterworth;Marion MacFarlane

  291
  Citations

• Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

  Nicholas Harper;Michelle Hughes;Marion MacFarlane;Gerald M. Cohen

  288
  Citations

• Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

  Marion MacFarlane;Nicholas Harper;Roger T Snowden;Martin J S Dyer

  284
  Citations

• Initiation of Apaf-1 translation by internal ribosome entry

  Mark J Coldwell;Sally A Mitchell;Mark Stoneley;Marion MacFarlane

  280
  Citations

• Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

  Michelle A. Hughes;Ian R. Powley;Rebekah Jukes-Jones;Sebastian Horn

  253
  Citations