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Overview

A. John Rush is affiliated with Duke University in the United States and conducts research primarily within the fields of Medicine and Psychology. Their work spans various subfields, including Pharmacology, Clinical Psychology, Psychiatry and Mental Health, Experimental and Cognitive Psychology, and Surgery.

Their research topics focus on:

  • Treatment of Major Depression
  • Mental Health Research Topics
  • Tryptophan and Brain Disorders
  • Functional Brain Connectivity Studies
  • Schizophrenia Research and Treatment
  • Child and Adolescent Psychosocial and Emotional Development
  • Mental Health Treatment and Access

Recent notable papers authored by or associated with A. John Rush include:

  • Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression, 2022, New England Journal of Medicine
  • Bupropion and Naltrexone in Methamphetamine Use Disorder, 2021, New England Journal of Medicine
  • Antidepressant Side Effects and Their Impact on Treatment Outcome in People with Major Depressive Disorder: An iSPOT-D Report, 2021, Translational Psychiatry
  • Functional Neuroanatomical Correlates of Traumatic Stress Revisited 7 Years Later, This Time with Data, 2025, Psychopharmacology Bulletin
  • Antipsychotic-Induced Hyperprolactinemia and Sexual Dysfunction, 2025, Psychopharmacology Bulletin

Frequent collaborators in their research include:

  • Madhukar H. Trivedi
  • Boadie W. Dunlop
  • Rima Kaddurah-Daouk
  • Sudeepa Bhattacharyya
  • Harold A. Sackeïm

A. John Rush's publications frequently appear in the following venues:

  • Psychopharmacology Bulletin
  • Journal of Affective Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Brain Stimulation

Best Publications

  • The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).

    Ronald C. Kessler;Patricia Berglund;Olga Demler;Robert Jin

  • Acute and Longer- Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

    A. John Rush;Madhukar H. Trivedi;Stephen R. Wisniewski;Andrew A. Nierenberg

  • The 16-Item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression.

    A.John Rush;Madhukar H Trivedi;Hicham M Ibrahim;Thomas J Carmody

  • Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice

    Madhukar H. Trivedi;A. John Rush;Stephen R. Wisniewski;Andrew A. Nierenberg

  • The Inventory of Depressive Symptomatology (IDS): Psychometric properties.

    A. J. Rush;C. M. Gullion;M. R. Basco;Robin B Jarrett

  • Conceptualization and Rationale for Consensus Definitions of Terms in Major Depressive Disorder: Remission, Recovery, Relapse, and Recurrence

    Ellen Frank;Robert F. Prien;Robin B. Jarrett;Martin B. Keller

  • A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression.

    Martin B. Keller;James P. McCullough;Daniel N. Klein;Bruce Arnow

  • A Double-blind, Randomized, Placebo-Controlled Trial of Fluoxetine in Children and Adolescents With Depression

    Graham J. Emslie;A. John Rush;Warren A. Weinberg;Robert A. Kowatch

  • Comparative efficacy of cognitive therapy and pharmacotherapy in the treatment of depressed outpatients

    Augustus J. Rush;Aaron T. Beck;Maria Kovacs;Steven Hollon

  • Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression.

    A. John Rush;Madhukar H. Trivedi;Stephen R. Wisniewski;Jonathan W. Stewart

  • The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: a psychometric evaluation.

    Madhukar H. Trivedi;A. J. Rush;A. J. Rush;H. M. Ibrahim;H. M. Ibrahim;T. J. Carmody

  • Medication Augmentation after the Failure of Ssris for Depression

    Madhukar H Trivedi;Maurizio Fava;Stephen R. Wisniewski;Michael E. Thase

  • Efficacy of Divalproex vs Lithium and Placebo in the Treatment of Mania

    Charles L. Bowden;Andrew M. Brugger;Alan C. Swann;Joseph R. Calabrese

  • Sequenced treatment alternatives to relieve depression (STAR * D): rationale and design

    A.John Rush;Maurizio Fava;Stephen R Wisniewski;Philip W Lavori

  • The Inventory for Depressive Symptomatology (IDS): preliminary findings.

    A. John Rush;Donna E. Giles;Michael A. Schlesser;Carl L. Fulton

  • Difference in treatment outcome in outpatients with anxious versus nonanxious depression: a STAR*D report.

    Maurizio Fava;A. John Rush;Jonathan E. Alpert;G. K. Balasubramani

  • Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder

    Susan L. McElroy;Lori L. Altshuler;Trisha Suppes;Paul E. Keck

  • Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study.

    A. John Rush;Mark S. George;Mark S. George;Harold A. Sackeim;Lauren B. Marangell

  • Remissions in maternal depression and child psychopathology: A STAR*D-child report

    Myrna M. Weissman;Daniel J. Pilowsky;Priya J. Wickramaratne;Ardesheer Talati

  • The STAR*D project results: A comprehensive review of findings

    Diane Warden;A. John Rush;Madhukar H. Trivedi;Maurizio Fava

Frequent Co-Authors

Madhukar H. Trivedi
Madhukar H. Trivedi The University of Texas Southwestern Medical Center
Stephen R. Wisniewski
Stephen R. Wisniewski University of Pittsburgh
Maurizio Fava
Maurizio Fava Harvard University
Michael E. Thase
Michael E. Thase University of Pennsylvania
Melanie M. Biggs
Melanie M. Biggs The University of Texas Southwestern Medical Center
Thomas J. Carmody
Thomas J. Carmody The University of Texas Southwestern Medical Center
Andrew A. Nierenberg
Andrew A. Nierenberg Harvard University
Trisha Suppes
Trisha Suppes Stanford University
Jonathan E. Alpert
Jonathan E. Alpert Harvard University
Howard P. Roffwarg
Howard P. Roffwarg University of Mississippi Medical Center

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