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Biology and Biochemistry

D-Index
77
Citations
34417
World Ranking
4681
National Ranking
350

Overview

Richard A. Knight is affiliated with University College London in the United Kingdom. Their research spans several main fields and subfields, chiefly within biochemistry, genetics, molecular biology, and medicine. Specific subfields of study include molecular biology, oncology, nephrology, dermatology, and the endocrine and autonomic systems.

Research topics covered by Knight include:

  • Epigenetics and DNA methylation
  • Cancer-related molecular pathways
  • Single-cell and spatial transcriptomics
  • Renal and related cancers
  • Chronic kidney disease and diabetes
  • Genomics and chromatin dynamics
  • Cancer-related gene regulation

Knight's work has been published in a range of scientific venues. These include:

  • Nature
  • Oncogene
  • Cell Reports
  • Science Advances
  • Proceedings of the National Academy of Sciences

Recent papers authored or co-authored by Knight are:

  • "An atlas of healthy and injured cell states and niches in the human kidney," 2023, Nature
  • "ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes," 2020, Oncogene
  • "Metabolic regulation by p53 prevents R-loop-associated genomic instability," 2022, Cell Reports
  • "The C terminus of p73 is essential for hippocampal development," 2020, Proceedings of the National Academy of Sciences
  • "ZFP750 affects the cutaneous barrier through regulating lipid metabolism," 2023, Science Advances

Frequent collaborators in Knight's research include:

  • Gerry Melino
  • Ivano Amelio
  • Alessio Butera
  • Massimiliano Agostini
  • Emanuele Panatta

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

    G. Kroemer;G. Kroemer;G. Kroemer;L. Galluzzi;L. Galluzzi;L. Galluzzi;P. Vandenabeele;J. Abrams

  • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

    Galluzzi L;Vitale I;Vitale I;Vitale I;Abrams Jm;Alnemri Es

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • miR-203 represses 'stemness' by repressing DeltaNp63.

    A M Lena;R Shalom-Feuerstein;P Rivetti di Val Cervo;D Aberdam

  • S -nitrosylation regulates apoptosis

    Gerry Melino;Francesca Bernassola;Richard A. Knight;Maria Tiziana Corasaniti

  • p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation.

    Gerry Melino;Gerry Melino;Francesca Bernassola;Marco Ranalli;Karen Yee

  • Apoptosis of Endothelial Cells Precedes Myocyte Cell Apoptosis in Ischemia/Reperfusion Injury

    Tiziano Scarabelli;Anastasis Stephanou;Neil Rayment;Evasio Pasini

  • Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury

    Lauren Valentim;Kevin M. Laurence;Paul A. Townsend;Christopher J. Carroll

  • Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

    E Candi;A Rufini;A Terrinoni;D Dinsdale

  • Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

    Paola Tucci;Massimiliano Agostini;Francesca Grespi;Francesca Grespi;Francesca Grespi;Elke K Markert

  • STAT-1 Interacts with p53 to Enhance DNA Damage-induced Apoptosis

    Paul A. Townsend;Tiziano M. Scarabelli;Sean M. Davidson;Richard A. Knight

  • Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway.

    Bhawanjit K. Brar;Anna K. Jonassen;Anastasis Stephanou;Giorgia Santilli

  • miR-34: from bench to bedside

    Massimiliano Agostini;Richard A. Knight

  • The E3 ubiquitin ligase Itch controls the protein stability of p63

    Mario Rossi;Rami I. Aqeilan;Michael Neale;Eleonora Candi

  • Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis

    Anastasis Stephanou;Bhawanjit K. Brar;Tiziano M. Scarabelli;Anna K. Jonassen

  • MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines.

    Giuditta Viticchiè;Anna Maria Lena;Alessia Latina;Amanda Formosa

  • Induction of Apoptosis and Fas Receptor/Fas Ligand Expression by Ischemia/Reperfusion in Cardiac Myocytes Requires Serine 727 of the STAT-1 Transcription Factor but Not Tyrosine 701

    Anastasis Stephanou;Tiziano M. Scarabelli;Bhawanjit K. Brar;Yoshinobu Nakanishi

  • Necroptosis: STAT3 kills?

    Vassilis Georgiadis;Richard A. Knight

Frequent Co-Authors

Gerry Melino
Gerry Melino University of Rome Tor Vergata
Anastasis Stephanou
Anastasis Stephanou European University Cyprus
David S. Latchman
David S. Latchman University College London
Paul A. Townsend
Paul A. Townsend University of Manchester
Eleonora Candi
Eleonora Candi University of Rome Tor Vergata
David Dinsdale
David Dinsdale University of Leicester
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Peter Vandenabeele
Peter Vandenabeele Ghent University

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