Mahavir Singh

Overview

Best Publications

• Stimulation of Th1-Polarizing Cytokines, C-C Chemokines, Maturation of Dendritic Cells, and Adjuvant Function by the Peptide Binding Fragment of Heat Shock Protein 70

  Yufei Wang;Charles G. Kelly;Mahavir Singh;Edward G. McGowan

  384
  Citations

• A Conserved Mycobacterial Heat Shock Protein (hsp) 70 Sequence Prevents Adjuvant Arthritis upon Nasal Administration and Induces IL-10-Producing T Cells That Cross-React with the Mammalian Self-hsp70 Homologue

  Uwe Wendling;Liesbeth Paul;Ruurd van der Zee;Berent Prakken

  305
  Citations

• Mycobacterium tuberculosis heat shock proteins use diverse Toll-like receptor pathways to activate pro-inflammatory signals.

  Yonca Bulut;Kathrin S. Michelsen;Linda Hayrapetian;Yoshikazu Naiki

  297
  Citations

• PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress

  Joshua K. Salabei;Timothy D. Cummins;Mahavir Singh;Steven P. Jones

  241
  Citations

• Early Depletion of Mycobacterium tuberculosis-Specific T Helper 1 Cell Responses after HIV-1 Infection

  Christof Geldmacher;Alexandra Schuetz;Njabulo Ngwenyama;Joseph P. Casazza

  230
  Citations

• Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis.

  Timo Jaeger;Heike Budde;Leopold Flohé;Ulrich Menge

  210
  Citations

• Dendritic Cell Stimulation by Mycobacterial Hsp70 Is Mediated Through CCR5

  R. Andres Floto;Paul A. MacAry;Paul A. MacAry;Jessica M. Boname;Tan Suet Mien

  204
  Citations

• Mycobacterium tuberculosis chaperonin 60.1 is a more potent cytokine stimulator than chaperonin 60.2 (Hsp 65) and contains a CD14-binding domain.

  Jo C. Lewthwaite;Anthony R. M. Coates;Peter Tormay;Mahavir Singh

  187
  Citations

• Functions and specificity of T cells following nucleic acid vaccination of mice against Mycobacterium tuberculosis infection.

  X Zhu;N Venkataprasad;H S Thangaraj;M Hill

  175
  Citations

• Oxidative and reductive metabolism of lipid-peroxidation derived carbonyls.

  Mahavir Singh;Aniruddh Kapoor;Aruni Bhatnagar

  164
  Citations

• Heat shock protein 70 is a potent activator of the human complement system.

  Zoltán Prohászka;Mahavir Singh;Kálmán Nagy;Emese Kiss

  161
  Citations

• 3-Ketosteroid 9alpha-hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis.

  Yanmin Hu;Robert van der Geize;Gurdyal S. Besra;Sudagar S. Gurcha

  158
  Citations

• Whole-Blood Flow-Cytometric Analysis of Antigen-Specific CD4 T-Cell Cytokine Profiles Distinguishes Active Tuberculosis from Non-Active States

  Urban Sester;Mathias Fousse;Jan-Henning Dirks;Ulrich Mack

  149
  Citations

• Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis.

  Wendy Xolalpa;Antonio J. Vallecillo;Martha Lara;Guillermo Mendoza-Hernandez

  147
  Citations

• HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation.

  Paul A MacAry;Babak Javid;R.Andres Floto;Kenneth G.C Smith

  147
  Citations

• Activation of T cells recognizing an epitope of heat-shock protein 70 can protect against rat adjuvant arthritis.

  Shigehisa Tanaka;Yuki Kimura;Akio Mitani;Genta Yamamoto;Genta Yamamoto

  146
  Citations

• Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis

  Martijn J. C. van Herwijnen;Lotte Wieten;Ruurd van der Zee;Peter J. van Kooten

  138
  Citations

• Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex.

  Robert Schnell;Wulf Oehlmann;Mahavir Singh;Gunter Schneider

  135
  Citations

• Human T- and B-cell reactivity to the 16kDa alpha-crystallin protein of Mycobacterium tuberculosis.

  R. J. Wilkinson;K. A. Wilkinson;K. A. L. De Smet;K. Haslov

  131
  Citations

• Functional domains of HSP70 stimulate generation of cytokines and chemokines, maturation of dendritic cells and adjuvanticity.

  Tom Lehner;Yufei Wang;Trevor Whittall;E McGowan

  130
  Citations