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Immunology

D-Index
62
Citations
12535
World Ranking
3153
National Ranking
121

Overview

Willem van Eden is affiliated with Utrecht University in the Netherlands, where their work spans several interconnected fields within biological and medical sciences. Their research contributions cover Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology, with a focus on several specialized subfields including Immunology, Microbiology, Molecular Biology, Infectious Diseases, and Agronomy and Crop Science.

The researcher's topics of study emphasize immunotherapy and immune responses, heat shock proteins research, antimicrobial peptides and activities, immune response and inflammation, microbial infections and disease research, CAR-T cell therapy research, and viral gastroenteritis research and epidemiology.

Van Eden's recent scholarly papers demonstrate a broad engagement with inflammation and immune mechanisms across different biological models and contexts. Selected recent papers include:

  • Transcriptome Analysis of The Inflammatory Responses of Bovine Mammary Epithelial Cells: Exploring Immunomodulatory Target Genes for Bovine Mastitis (2020, Pathogens)
  • Goals in Nutrition Science 2020-2025 (2021, Frontiers in Nutrition)
  • Hsp70 and NF-kB Mediated Control of Innate Inflammatory Responses in a Canine Macrophage Cell Line (2020, International Journal of Molecular Sciences)
  • In vitro Chicken Bone Marrow-Derived Dendritic Cells Comprise Subsets at Different States of Maturation (2020, Frontiers in Immunology)
  • COVID-19 vaccines: the importance of transparency and fact-based education (2020, British Journal of Clinical Pharmacology)

Frequent co-authors collaborating with van Eden include:

  • Victor P. M. G. Rutten
  • Femke Broere
  • Robin H. G. A. van den Biggelaar
  • Christine A. Jansen
  • Arie Jan Stoppelenburg

Publication venues where van Eden's work is regularly featured include:

  • Frontiers in Nutrition
  • Vaccines
  • Pathogens
  • International Journal of Molecular Sciences
  • Frontiers in Immunology

Their work contributes to the understanding of immune system regulation, inflammatory pathways, and molecular biology related to infection and immunity. These areas are pivotal in advancing approaches in immunotherapy, understanding heat shock proteins in disease contexts, and evaluating responses to microbial infections and vaccines.

Best Publications

  • Heat-shock proteins induce T-cell regulation of chronic inflammation.

    Willem van Eden;Ruurd van der Zee;Berent Prakken

  • Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

    Kamran Ghoreschi;Peter Thomas;Susanne Breit;Martin Dugas

  • Mechanisms of disease: the hygiene hypothesis revisited.

    Francisco Guarner;Raphaëlle Bourdet-Sicard;Per Brandtzaeg;Harsharnjit S. Gill

  • Synovial fluid T cell reactivity against 65 kD heat shock protein of mycobacteria in early chronic arthritis.

    PieterC.M. Res;FerdinandC. Breedveld;JanD.A. Van Embden;CeesG. Schaar

  • Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis.

    S. M. Anderton;R. Van Der Zee;Berent Prakken;A. Noordzij

  • The anti-inflammatory mechanisms of Hsp70

    Thiago J Borges;Lotte Wieten;Martijn J. C. van Herwijnen;Femke Broere

  • A Conserved Mycobacterial Heat Shock Protein (hsp) 70 Sequence Prevents Adjuvant Arthritis upon Nasal Administration and Induces IL-10-Producing T Cells That Cross-React with the Mammalian Self-hsp70 Homologue

    Uwe Wendling;Liesbeth Paul;Ruurd van der Zee;Berent Prakken

  • Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.

    Bram Slütter;Suzanne Bal;Chantal Keijzer;Roel Mallants

  • The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis.

    V M Corrigall;M D Bodman-Smith;M S Fife;B Canas

  • Heat-shock proteins as immunogenic bacterial antigens with the potential to induce and regulate autoimmune arthritis

    Willem Van Eden

  • Do heat shock proteins control the balance of T-cell regulation in inlammatory diseases?

    Willem van Eden;Ruurd van der Zee;Alberta G.A Paul;Berent J Prakken

  • T cell subsets and T cell-mediated immunity

    Femke Broere;Sergei G. Apasov;Michail V. Sitkovsky;Willem van Eden

  • T lymphocyte clones illuminate pathogenesis and affect therapy of experimental arthritis.

    Irun R. Cohen;Joseph Holoshitz;Willem van Eden;Ayalla Frenkel

  • Anergic T cells actively suppress T cell responses via the antigen‐presenting cell

    L. S. Taams;A. J. M. L. Van Rensen;M. C. M. Poelen;C. A. C. M. Van Els

  • Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis

    Berent J. Prakken;Ruurd van der Zee;Stephen M. Anderton;Peter J. S. van Kooten

  • Juvenile chronic arthritis: T cell reactivity to human HSP60 in patients with a favorable course of arthritis.

    E. R. De Graeff-Meeder;W. Van Eden;G. T. Rijkers;B. J. Prakken

  • Stress, heat shock proteins, and autoimmunity: how immune responses to heat shock proteins are to be used for the control of chronic inflammatory diseases.

    Willem Van Eden;George Wick;Salvatore Albani;Irun Cohen

  • Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells

    Elisabeth Hermann;Ansgar W. Lohse;Ruurd Van Der Zee;Willem Van Eden

  • Stress Proteins in Medicine

    Willem van Eden;Douglas B. Young

  • Evidence for an HLA-DR4-associated immune-response gene for Mycobacterium tuberculosis. A clue to the pathogenesis of rheumatoid arthritis?

    TomH.M Ottenhoff;Pedro Torres;JoseTerencio De Las Aguas;Ramon Fernandez

Frequent Co-Authors

Ruurd van der Zee
Ruurd van der Zee Utrecht University
Marca H. M. Wauben
Marca H. M. Wauben Utrecht University
Victor P.M.G. Rutten
Victor P.M.G. Rutten University of Pretoria
Berent J. Prakken
Berent J. Prakken Utrecht University
Catharien M. U. Hilkens
Catharien M. U. Hilkens Newcastle University
Irun R. Cohen
Irun R. Cohen Weizmann Institute of Science
Stephen M. Anderton
Stephen M. Anderton University of Edinburgh
Alice J. A. M. Sijts
Alice J. A. M. Sijts Utrecht University
Leonie S. Taams
Leonie S. Taams King's College London
John D. Isaacs
John D. Isaacs Newcastle University

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