Catharien M. U. Hilkens mainly investigates Immunology, Cytokine, Interleukin 12, Cell biology and T cell. Immunology is frequently linked to Cellular differentiation in her study. Her work carried out in the field of Cytokine brings together such families of science as Endocrinology, Immune system, Immunotherapy and Antigen.
Her Interleukin 12 research includes elements of CD40 and Antigen-presenting cell. Her research in Cell biology intersects with topics in Prostaglandin E2, Gene and Cell growth. The T cell study which covers Secretion that intersects with Mesenchymal stem cell, Clonogenic assay and Cell therapy.
The scientist’s investigation covers issues in Immunology, T cell, Cytokine, Cell biology and Immune system. Her study involves Immune tolerance, Dendritic cell, Arthritis, Antigen and Immunotherapy, a branch of Immunology. Her work on IL-2 receptor as part of general T cell study is frequently linked to Population, therefore connecting diverse disciplines of science.
Her work in Cytokine addresses subjects such as Antigen-presenting cell, which are connected to disciplines such as Interleukin 4. Her Cell biology research incorporates themes from CD40, Phenotype, Stimulation, T-cell receptor and Interleukin 12. Her Immune system research incorporates elements of Inflammation and Cell.
Immunology, Arthritis, Population, T cell and Immune tolerance are her primary areas of study. Her Gene signature research extends to the thematically linked field of Immunology. Her Gene signature research is multidisciplinary, incorporating perspectives in Whole blood, CD40, Downregulation and upregulation, CD8 and Initial therapy.
Her Arthritis research is multidisciplinary, incorporating elements of Epitope and IL-2 receptor. The various areas that Catharien M. U. Hilkens examines in her Immune tolerance study include Clinical trial and Transplantation. Her research integrates issues of Cell activation, Cytokine secretion and Inflammatory arthritis in her study of Antigen.
Catharien M. U. Hilkens mostly deals with CD86, Cancer research, Transplantation, Cell therapy and Macrophage. Catharien M. U. Hilkens interconnects Whole blood, CD40, Interferon, Downregulation and upregulation and CD8 in the investigation of issues within CD86. Her Cancer research study combines topics from a wide range of disciplines, such as Inflammation, Proliferation Marker, Macrophage proliferation and Pathogenesis.
Her work deals with themes such as Chimeric antigen receptor, Immunotherapy and Neuroscience, which intersect with Transplantation. The Cell therapy study combines topics in areas such as Clinical trial, Bioinformatics and Immune tolerance.
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T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal.
Pawel Kaliński;Catharien M.U Hilkens;Eddy A Wierenga;Martien L Kapsenberg.
Immunology Today (1999)
IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses
Andreas Schlitzer;Naomi McGovern;Pearline Teo;Teresa Zelante.
Immunity (2013)
IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells.
P. Kalinski;C.M.U. Hilkens;A. Snijders;F.G.M. Snijdewint.
Journal of Immunology (1997)
α-Type-1 Polarized Dendritic Cells A Novel Immunization Tool with Optimized CTL-inducing Activity
Robbie B. Mailliard;Anna Wankowicz-Kalinska;Quan Cai;Amy Wesa.
Cancer Research (2004)
Prostaglandin E2 Induces the Final Maturation of IL-12-Deficient CD1a+CD83+ Dendritic Cells: The Levels of IL-12 Are Determined During the Final Dendritic Cell Maturation and Are Resistant to Further Modulation
Paweł Kaliński;Joost H. N. Schuitemaker;Catharien M. U. Hilkens;Martien L. Kapsenberg.
Journal of Immunology (1998)
High-level IL-12 production by human dendritic cells requires two signals.
Alies Snijders;Pawel Kalinski;Catharien M. U. Hilkens;Martien L. Kapsenberg.
International Immunology (1998)
Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells
Muzlifah A. Haniffa;Xiao-Nong Wang;Udo Holtick;Michelle Rae.
Journal of Immunology (2007)
Human Dendritic Cells Require Exogenous Interleukin-12–Inducing Factors to Direct the Development of Naive T-Helper Cells Toward the Th1 Phenotype
C.M.U. Hilkens;P. Kalinski;M. de Boer;M.L. Kapsenberg.
Blood (1997)
Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells
Paweł Kaliński;Joost H. N. Schuitemaker;Catharien M. U. Hilkens;Eddy A. Wierenga.
Journal of Immunology (1999)
Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ Study
Joanna Collerton;Carmen Martin-Ruiz;Karen Davies;Catharien M. Hilkens.
Mechanisms of Ageing and Development (2012)
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