Eddy A. Wierenga

Overview

Best Publications

• T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal.

  Pawel Kaliński;Catharien M.U Hilkens;Eddy A Wierenga;Martien L Kapsenberg

  1309
  Citations

• Evidence for compartmentalization of functional subsets of CD2+ T lymphocytes in atopic patients

  E A Wierenga;M Snoek;C de Groot;I Chrétien

  1134
  Citations

• Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

  H.M. Diepolder;R. Zachoval;R.M. Hoffmann;M-C. Jung

  1059
  Citations

• Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.

  Marcel B.M. Teunissen;Jan D. Bos;Cock W. Koomen;Rene de Waal Malefyt

  875
  Citations

• Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.

  Hermelijn H Smits;Anneke Engering;Desiree van der Kleij;Esther C de Jong

  734
  Citations

• Development of Th1-Inducing Capacity in Myeloid Dendritic Cells Requires Environmental Instruction

  P L Vieira;E C de Jong;E A Wierenga;M L Kapsenberg

  718
  Citations

• Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals

  Esther C. de Jong;Pedro L. Vieira;Pawel Kalinski;Joost H. N. Schuitemaker

  685
  Citations

• Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes.

  F. G. M. Snijdewint;P. Kalinski;E. A. Wierenga;J. D. Bos

  655
  Citations

• High frequency of IL-4-producing CD4+ allergen-specific T lymphocytes in atopic dermatitis lesional skin.

  Frans L van der Heijden;Eddy A Wierenga;Jan D Bos;Martien L Kapsenberg

  539
  Citations

• Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection.

  H M Diepolder;J T Gerlach;R Zachoval;R M Hoffmann

  424
  Citations

• Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells

  Paweł Kaliński;Joost H. N. Schuitemaker;Catharien M. U. Hilkens;Eddy A. Wierenga

  399
  Citations

• Human atopen-specific types 1 and 2 T helper cell clones

  E. A. Wierenga;M. Snoek;H. M. Jansen;J. D. Bos

  348
  Citations

• Functional subsets of allergen-reactive human CD4+ T cells

  Martien L Kapsenberg;Eddy A Wierenga;Jan D Bos;Henk M Jansen

  330
  Citations

• Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells.

  Pedro L. Vieira;Heleen C. Heystek;Jan Wormmeester;Eddy A. Wierenga

  301
  Citations

• Th1 Lymphokine Production Profiles of Nickel-Specific CD4+ T-Lymphocyte Clones from Nickel Contact Allergic and Non-Allergic Individuals

  Martien L Kapsenberg;Eddy A Wierenga;Frank E.M. Stiekema;Anke M.B.C. Tiggelman

  265
  Citations

• Glucocorticoids Inhibit Bioactive IL-12p70 Production by In Vitro-Generated Human Dendritic Cells Without Affecting Their T Cell Stimulatory Potential

  P L Vieira;P Kaliński;E A Wierenga;M L Kapsenberg

  259
  Citations

• Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development.

  Hermelijn H Smits;Astrid J van Beelen;Christina Hessle;Robert Westland

  254
  Citations

• Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection.

  M C Jung;H M Diepolder;U Spengler;E A Wierenga

  229
  Citations

• Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin‐2

  CM Hilkens;H Vermeulen;van, Neerven, Rj;FG Snijdewint

  215
  Citations

• IL-4 is a mediator of IL-12p70 induction by human Th2 cells: reversal of polarized Th2 phenotype by dendritic cells.

  P. Kaliński;H. H. Smits;J. H. Schuitemaker;P. L. Vieira

  204
  Citations

• The paradigm of type 1 and type 2 antigen-presenting cells. Implications for atopic allergy

  M. L. Kapsenberg;C. M. U. Hilkens;E. A. Wierenga;P. Kalinski

  201
  Citations