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Immunology

D-Index
78
Citations
24370
World Ranking
1742
National Ranking
857

Overview

Pawel Kalinski is affiliated with the Roswell Park Comprehensive Cancer Center in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a particular focus on Oncology and Immunology as main subfields. Additional research interests involve Pulmonary and Respiratory Medicine, Molecular Biology, and Surgery.

The scientist's work covers a broad range of topics related to cancer and immune response, including:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Chemokine receptors and signaling
  • Brain Metastases and Treatment
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Ferroptosis and cancer prognosis

Pawel Kalinski has contributed to numerous publications, with key papers including:

  • "Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer," published in 2022 in Cancer Cell
  • "Plasmacytoid Dendritic Cell (pDC) Infiltration Correlate with Tumor Infiltrating Lymphocytes, Cancer Immunity, and Better Survival in Triple Negative Breast Cancer (TNBC) More Strongly than Conventional Dendritic Cell (cDC)," published in 2020 in Cancers
  • "Improving cancer immunotherapy by rationally combining oncolytic virus with modulators targeting key signaling pathways," published in 2022 in Molecular Cancer
  • "High intratumoral CD8+ T-cell infiltration is associated with improved survival in prostate cancer patients undergoing radical prostatectomy," published in 2020 in The Prostate
  • "Dendritic cell vaccines targeting tumor blood vessel antigens in combination with dasatinib induce therapeutic immune responses in patients with checkpoint-refractory advanced melanoma," published in 2021 in Journal for ImmunoTherapy of Cancer

The scientist often collaborates with a select group of frequent co-authors who have contributed to multiple works together, including:

  • Shipra Gandhi
  • Kazuaki Takabe
  • Kristopher Attwood
  • Mateusz Opyrchal
  • Brian J. Czerniecki

The most common venues for Pawel Kalinski's publications are:

  • Cancer Research
  • Journal of Clinical Oncology
  • Regular and Young Investigator Award Abstracts
  • Cancers
  • Journal for ImmunoTherapy of Cancer

Best Publications

  • Regulation of Immune Responses by Prostaglandin E2

    Pawel Kalinski

  • T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal.

    Pawel Kaliński;Catharien M.U Hilkens;Eddy A Wierenga;Martien L Kapsenberg

  • Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma.

    Hideho Okada;Pawel Kalinski;Ryo Ueda;Aki Hoji

  • IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells.

    P. Kalinski;C.M.U. Hilkens;A. Snijders;F.G.M. Snijdewint

  • Development of Th1-Inducing Capacity in Myeloid Dendritic Cells Requires Environmental Instruction

    P L Vieira;E C de Jong;E A Wierenga;M L Kapsenberg

  • Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals

    Esther C. de Jong;Pedro L. Vieira;Pawel Kalinski;Joost H. N. Schuitemaker

  • Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes.

    F. G. M. Snijdewint;P. Kalinski;E. A. Wierenga;J. D. Bos

  • α-Type-1 Polarized Dendritic Cells A Novel Immunization Tool with Optimized CTL-inducing Activity

    Robbie B. Mailliard;Anna Wankowicz-Kalinska;Quan Cai;Amy Wesa

  • Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells.

    Nataša Obermajer;Ravikumar Muthuswamy;Jamie Lesnock;Robert P. Edwards

  • Immunotherapy of Cancer in 2012

    John M. Kirkwood;Lisa H. Butterfield;Ahmad A. Tarhini;Hassane Zarour

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Prostaglandin E2 Induces the Final Maturation of IL-12-Deficient CD1a+CD83+ Dendritic Cells: The Levels of IL-12 Are Determined During the Final Dendritic Cell Maturation and Are Resistant to Further Modulation

    Paweł Kaliński;Joost H. N. Schuitemaker;Catharien M. U. Hilkens;Martien L. Kapsenberg

  • High-level IL-12 production by human dendritic cells requires two signals.

    Alies Snijders;Pawel Kalinski;Catharien M. U. Hilkens;Martien L. Kapsenberg

  • Prostaglandin E2 is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer

    Paweł Kaliński;Pedro L. Vieira;Joost H. N. Schuitemaker;Esther C. de Jong

  • PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment.

    Nataša Obermajer;Ravikumar Muthuswamy;Kunle O. Odunsi;Robert P. Edwards

  • Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.

    Unknown

  • Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function.

    Robbie B. Mailliard;Young Ik Son;Richard Redlinger;Patrick T. Coates

  • Human Dendritic Cells Require Exogenous Interleukin-12–Inducing Factors to Direct the Development of Naive T-Helper Cells Toward the Th1 Phenotype

    C.M.U. Hilkens;P. Kalinski;M. de Boer;M.L. Kapsenberg

  • Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells

    Paweł Kaliński;Joost H. N. Schuitemaker;Catharien M. U. Hilkens;Eddy A. Wierenga

  • Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy.

    Zuqiang Liu;Roshni Ravindranathan;Pawel Kalinski;Z. Sheng Guo

  • Th1/Th2 balance in cancer, transplantation and pregnancy.

    Michael R. Shurin;Lina Lu;Pawel Kalinski;Ann M. Stewart-Akers

  • IL-18-induced CD83+CCR7+ NK helper cells.

    Robbie B. Mailliard;Sean M. Alber;Hongmei Shen;Simon C. Watkins

Frequent Co-Authors

Martien L. Kapsenberg
Martien L. Kapsenberg University of Amsterdam
David L. Bartlett
David L. Bartlett University of Pittsburgh
Michael T. Lotze
Michael T. Lotze University of Pittsburgh
John M. Kirkwood
John M. Kirkwood University of Pittsburgh
Walter J. Storkus
Walter J. Storkus University of Pittsburgh
Lisa H. Butterfield
Lisa H. Butterfield University of California, San Francisco
Hideho Okada
Hideho Okada University of California, San Francisco
Catharien M. U. Hilkens
Catharien M. U. Hilkens Newcastle University
Herbert J. Zeh
Herbert J. Zeh The University of Texas Southwestern Medical Center
Eddy A. Wierenga
Eddy A. Wierenga University of Amsterdam

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