D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 52 Citations 15,896 108 World Ranking 3373 National Ranking 1618

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Genetics

Teepu Siddique focuses on Amyotrophic lateral sclerosis, Genetics, SOD1, Mutation and Genetic linkage. His work on TARDBP and UBQLN2 as part of general Amyotrophic lateral sclerosis research is frequently linked to RNA-Binding Protein FUS, thereby connecting diverse disciplines of science. His study explores the link between Genetics and topics such as Frontotemporal dementia that cross with problems in Penetrance and Haplotype.

His SOD1 research incorporates elements of Genetically modified mouse and Hyaline inclusion. His Mutation research incorporates themes from Internal medicine, Neurodegeneration, Endocrinology and Age of onset. He focuses mostly in the field of Genetic linkage, narrowing it down to topics relating to Chromosome 21 and, in certain cases, Linkage, Lod score, Paralysis, Pediatrics and Alzheimer's disease.

His most cited work include:

  • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. (1871 citations)
  • Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase (1285 citations)
  • Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia (814 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Amyotrophic lateral sclerosis, Genetics, SOD1, Neuroscience and Gene. His Amyotrophic lateral sclerosis study incorporates themes from Mutation and Neurodegeneration. His work deals with themes such as UBQLN2 and Protein degradation, which intersect with Mutation.

Locus, Genetic linkage, Gene mapping, Genetic marker and Genetic heterogeneity are the primary areas of interest in his Genetics study. His studies deal with areas such as Chromosome and Candidate gene as well as Locus. Within one scientific family, Teepu Siddique focuses on topics pertaining to Cell biology under SOD1, and may sometimes address concerns connected to Pathogenesis.

He most often published in these fields:

  • Amyotrophic lateral sclerosis (49.11%)
  • Genetics (43.75%)
  • SOD1 (20.09%)

What were the highlights of his more recent work (between 2012-2021)?

  • Amyotrophic lateral sclerosis (49.11%)
  • Genetics (43.75%)
  • Disease (12.95%)

In recent papers he was focusing on the following fields of study:

His main research concerns Amyotrophic lateral sclerosis, Genetics, Disease, Pathology and Cell biology. His Amyotrophic lateral sclerosis research is multidisciplinary, incorporating elements of C9orf72 and Neuroscience. Many of his research projects under Genetics are closely connected to Table with Table, tying the diverse disciplines of science together.

Teepu Siddique has included themes like Psychiatry and Bioinformatics in his Disease study. The various areas that Teepu Siddique examines in his Pathology study include Dermatology, Retinal, Central nervous system, Retina and Optic nerve. His studies in Cell biology integrate themes in fields like Transfection, Pathogenesis and LRRK2.

Between 2012 and 2021, his most popular works were:

  • Sporadic and hereditary amyotrophic lateral sclerosis (ALS). (120 citations)
  • Identification of TMEM230 mutations in familial Parkinson's disease (110 citations)
  • A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis (93 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Internal medicine

Teepu Siddique mainly focuses on Amyotrophic lateral sclerosis, Neuroscience, C9orf72, Disease and Genetics. His research integrates issues of Neuromuscular disease and Age of onset in his study of Amyotrophic lateral sclerosis. His Neuroscience research includes elements of Mutation, Alzheimer's disease, Epigenetics and Proteasome.

His C9orf72 research is multidisciplinary, relying on both Neurodegeneration, Charged multivesicular body protein 2B, Proband and SOD1. The various areas that Teepu Siddique examines in his Disease study include Therapeutic strategy, Neurology, Intracellular and Bioinformatics. His work deals with themes such as Molecular biology and Pathogenesis, which intersect with Genetics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.

T. J. Kwiatkowski;D. A. Bosco;D. A. Bosco;A. L. LeClerc;A. L. LeClerc;E. Tamrazian.
Science (2009)

2231 Citations

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

Han Xiang Deng;Afif Hentati;John A. Tainer;Zafar Iqbal.
Science (1993)

1698 Citations

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

Han-Xiang Deng;Wenjie Chen;Seong‐Tshool Hong;Seong‐Tshool Hong;Kym M Boycott.
Nature (2011)

1011 Citations

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

Ian R. A. Mackenzie;Eileen H. Bigio;Paul G. Ince;Felix Geser.
Annals of Neurology (2007)

923 Citations

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis.

Yi Yang;Afif Hentati;Han Xiang Deng;Omar Dabbagh.
Nature Genetics (2001)

842 Citations

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis.

Faisal Fecto;Jianhua Yan;S. Pavan Vemula;Erdong Liu.
JAMA Neurology (2011)

593 Citations

Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue.

Jenny S. Henkel;Joseph I. Engelhardt;László Siklós;Ericka P. Simpson.
Annals of Neurology (2004)

535 Citations

Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity.

T Siddique;D A Figlewicz;D A Figlewicz;M A Pericak-Vance;J L Haines.
The New England Journal of Medicine (1991)

495 Citations

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

Han Xiang Deng;Yong Shi;Yoshiaki Furukawa;Hong Zhai.
Proceedings of the National Academy of Sciences of the United States of America (2006)

485 Citations

Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2–21.3

Caroline Vance;Ammar Al-Chalabi;Deborah Ruddy;Bradley N. Smith.
Brain (2006)

442 Citations

Best Scientists Citing Teepu Siddique

Pamela J. Shaw

Pamela J. Shaw

University of Sheffield

Publications: 109

Christopher Shaw

Christopher Shaw

King's College London

Publications: 102

Guy A. Rouleau

Guy A. Rouleau

Montreal Neurological Institute and Hospital

Publications: 101

Ammar Al-Chalabi

Ammar Al-Chalabi

King's College London

Publications: 93

Peter M Andersen

Peter M Andersen

Umeå University

Publications: 93

Albert C. Ludolph

Albert C. Ludolph

University of Ulm

Publications: 85

Don W. Cleveland

Don W. Cleveland

University of California, San Diego

Publications: 79

Ian R. Mackenzie

Ian R. Mackenzie

University of British Columbia

Publications: 78

John Q. Trojanowski

John Q. Trojanowski

University of Pennsylvania

Publications: 72

Rosa Rademakers

Rosa Rademakers

Mayo Clinic

Publications: 70

Julie D. Atkin

Julie D. Atkin

Macquarie University

Publications: 67

David R. Borchelt

David R. Borchelt

University of Florida

Publications: 63

Orla Hardiman

Orla Hardiman

Trinity College Dublin

Publications: 61

Stanley H. Appel

Stanley H. Appel

Houston Methodist

Publications: 60

Manuela Neumann

Manuela Neumann

University of Tübingen

Publications: 58

Virginia M.-Y. Lee

Virginia M.-Y. Lee

University of Pennsylvania

Publications: 58

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

If you think any of the details on this page are incorrect, let us know.

Contact us
Something went wrong. Please try again later.