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Neuroscience

D-Index
65
Citations
12134
World Ranking
3180
National Ranking
1476

Overview

Charles J. Heckman is affiliated with Northwestern University in the United States. Their research primarily spans the fields of Neuroscience, Engineering, and Medicine, with notable contributions to subfields such as Biomedical Engineering, Cognitive Neuroscience, Cellular and Molecular Neuroscience, Neurology, and Pathology and Forensic Medicine.

The scientist's work focuses extensively on topics related to muscle activation and electromyography studies, neuroscience and neural engineering, motor control and adaptation, transcranial magnetic stimulation studies, EEG and brain-computer interfaces, neural dynamics and brain function, as well as spinal cord injury research.

Key recent papers authored include:

  • Estimates of persistent inward currents are reduced in upper limb motor units of older adults (2021) The Journal of Physiology
  • Estimates of persistent inward currents in lower limb motoneurons are larger in females than in males (2023) Journal of Neurophysiology
  • A geometric approach to quantifying the neuromodulatory effects of persistent inward currents on individual motor unit discharge patterns (2023) Journal of Neural Engineering
  • Differences in estimated persistent inward currents between ankle flexors and extensors in humans (2020) Journal of Neurophysiology
  • Inability to increase the neural drive to muscle is associated with task failure during submaximal contractions (2020) Journal of Neurophysiology

The venues in which Charles J. Heckman publishes frequently include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neurophysiology
  • The Journal of Physiology
  • The FASEB Journal
  • Journal of Neural Engineering

Regular collaborators in their research include:

  • Gregory E. P. Pearcey
  • James A. Beauchamp
  • Francesco Negro
  • Julius P. A. Dewald
  • Obaid U. Khurram

Best Publications

  • PERSISTENT INWARD CURRENTS IN MOTONEURON DENDRITES: IMPLICATIONS FOR MOTOR OUTPUT

    C. J. Heckman;Monica A. Gorassini;David J. Bennett

  • Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors

    Katherine C Murray;Aya Nakae;Marilee J Stephens;Michelle Rank

  • Bistability in Spinal Motoneurons In Vivo: Systematic Variations in Persistent Inward Currents

    R. H. Lee;C. J. Heckman

  • Persistent Inward Currents in Spinal Motoneurons and Their Influence on Human Motoneuron Firing Patterns

    C.J. Heckman;Michael Johnson;Carol Mottram;Jenna Schuster

  • Adjustable Amplification of Synaptic Input in the Dendrites of Spinal Motoneurons In Vivo

    Robert H. Lee;C. J. Heckman

  • Bistability in Spinal Motoneurons In Vivo: Systematic Variations in Rhythmic Firing Patterns

    R. H. Lee;C. J. Heckman

  • Motoneuron excitability: the importance of neuromodulatory inputs

    C.J. Heckman;Carol Mottram;Kathy Quinlan;Renee Theiss

  • Hyperexcitable dendrites in motoneurons and their neuromodulatory control during motor behavior.

    C.J. Heckman;Robert H. Lee;Robert M. Brownstone

  • Increased persistent Na+ current and its effect on excitability in motoneurones cultured from mutant SOD1 mice

    J. J. Kuo;T. Siddique;R. Fu;C. J. Heckman

  • The Physiological Control of Motoneuron Activity

    Marc D. Binder;C. J. Heckman;Randall K. Powers

  • Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice

    Jason J. Kuo;Martijn Schonewille;Teepu Siddique;Annet N. A. Schults

  • Progressive recruitment of contralesional cortico-reticulospinal pathways drives motor impairment post stroke.

    Jacob G. McPherson;Jacob G. McPherson;Albert Chen;Michael D. Ellis;Jun Yao

  • Motor neuron rescue in spinal muscular atrophy mice demonstrates that sensory-motor defects are a consequence, not a cause, of motor neuron dysfunction.

    Rocky G. Gogliotti;Katharina A. Quinlan;Courtenay B. Barlow;Christopher R. Heier

  • Influence of voltage-sensitive dendritic conductances on bistable firing and effective synaptic current in cat spinal motoneurons in vivo

    R. H. Lee;C. J. Heckman

  • Enhancement of Bistability in Spinal Motoneurons In Vivo by the Noradrenergic α1 Agonist Methoxamine

    R. H. Lee;C. J. Heckman

  • Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones.

    J. J. Kuo;R. H. Lee;L. Zhang;Charles J Heckman

  • Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity.

    Katherine C. Murray;Marilee J. Stephens;Edmund W. Ballou;Charles J. Heckman

  • Active properties of motoneurone dendrites: diffuse descending neuromodulation, focused local inhibition.

    C. J. Heckman;Allison S. Hyngstrom;Michael D. Johnson

  • Essential role of a fast persistent inward current in action potential initiation and control of rhythmic firing.

    R. H. Lee;C. J. Heckman

  • Computer simulation of the steady-state input-output function of the cat medial gastrocnemius motoneuron pool

    C. J. Heckman;M. D. Binder

  • Analysis of effective synaptic currents generated by homonymous Ia afferent fibers in motoneurons of the cat

    C. J. Heckman;M. D. Binder

Frequent Co-Authors

Randall K. Powers
Randall K. Powers University of Washington
Marc D. Binder
Marc D. Binder University of Washington
William Z. Rymer
William Z. Rymer Shirley Ryan AbilityLab
Alain Frigon
Alain Frigon Université de Sherbrooke
Eric J. Perreault
Eric J. Perreault Northwestern University
David J. Bennett
David J. Bennett University of Alberta
Dario Farina
Dario Farina Imperial College London
Teepu Siddique
Teepu Siddique Northwestern University
Monica A. Gorassini
Monica A. Gorassini University of Alberta
Alexander Meissner
Alexander Meissner Max Planck Institute for Molecular Genetics

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