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Medicine

D-Index
113
Citations
48910
World Ranking
4941
National Ranking
2679

Overview

Claudine Isaacs is affiliated with Georgetown University in the United States. Their research primarily focuses on medicine, with substantial contributions to biochemistry, genetics, and molecular biology. The main subfields of study include oncology, cancer research, pulmonary and respiratory medicine, genetics, and radiology, nuclear medicine, and imaging.

Their work covers a range of topics within cancer research, particularly related to breast cancer. The main topics include breast cancer treatment studies, advanced breast cancer therapies, cancer genomics and diagnostics, BRCA gene mutations in cancer, cancer treatment and pharmacology, HER2/EGFR in cancer research, and cancer immunotherapy and biomarkers.

Claudine Isaacs has collaborated frequently with several researchers. Notable co-authors include Laura J. Esserman, Christina Yau, Angela DeMichele, Douglas Yee, and Hope S. Rugo. These collaborations have yielded numerous publications over time.

The scientist has published extensively in several venues, with a strong presence in:

  • Cancer Research
  • Journal of Clinical Oncology
  • UNC Libraries
  • JAMA Oncology
  • Breast Cancer Research and Treatment

Significant recent papers authored include:

  • Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer, 2020, JAMA Oncology
  • Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion, 2021, Nature
  • Management of Hereditary Breast Cancer: American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Guideline, 2020, Journal of Clinical Oncology
  • Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial, 2021, Cancer Cell
  • Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer, 2020, JAMA Oncology

Best Publications

  • Prophylactic Oophorectomy in Carriers of BRCA1 or BRCA2 Mutations

    Timothy R. Rebbeck;Henry T. Lynch;Susan L. Neuhausen;Steven A. Narod

  • Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality

    Susan M. Domchek;Tara M. Friebel;Christian F. Singer;D. Gareth Evans

  • Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial.

    Saundra S. Buys;Edward Partridge;Amanda Black;Christine C. Johnson

  • Bilateral Prophylactic Mastectomy Reduces Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group

    Timothy R. Rebbeck;Tara Friebel;Henry T. Lynch;Susan L. Neuhausen

  • Prostate Cancer Screening in the Randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: Mortality Results after 13 Years of Follow-up

    Gerald L. Andriole;E. David Crawford;Robert L. Grubb;Saundra S. Buys

  • Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy

    Robert E. Schoen;Paul F. Pinsky;Joel L. Weissfeld;Lance A. Yokochi

  • Breast Cancer Risk After Bilateral Prophylactic Oophorectomy in BRCA1 Mutation Carriers

    Timothy R. Rebbeck;Albert M. Levin;Andrea Eisen;Carrie Snyder

  • Screening by Chest Radiograph and Lung Cancer Mortality: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Randomized Trial

    Martin M. Oken;Willam G. Hocking;Paul A. Kvale;Gerald L. Andriole

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • Risk-Reducing Salpingo-Oophorectomy for the Prevention of BRCA1- and BRCA2-Associated Breast and Gynecologic Cancer: A Multicenter, Prospective Study

    Noah D. Kauff;Susan M. Domchek;Tara M. Friebel;Mark E. Robson

  • Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk.

    T S Frank;S A Manley;O I Olopade;S Cummings

  • Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial

    Rita Nanda;Minetta C Liu;Christina Yau;Rebecca Shatsky

  • Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer

    Hope S. Rugo;Olufunmilayo I. Olopade;Angela DeMichele;Christina Yau

  • Everolimus for women with trastuzumab-resistant, HER2-positive, advanced breast cancer (BOLERO-3): a randomised, double-blind, placebo-controlled phase 3 trial

    Fabrice André;Ruth O'Regan;Mustafa Ozguroglu;Masakazu Toi

  • Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group

    Timothy R. Rebbeck;Tara Friebel;Theresa Wagner;Henry T. Lynch

  • Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: An International Case-Control Study

    Andrea Eisen;Jan Lubinski;Jan Klijn;Pal Moller

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  • BRCA1 Sequence Analysis in Women at High Risk for Susceptibility Mutations: Risk Factor Analysis and Implications for Genetic Testing

    Donna Shattuck-Eidens;Arnold Oliphant;Melody McClure;Celeste McBride

  • Cancer yield of mammography, MR, and US in high-risk women: prospective multi-institution breast cancer screening study.

    Constance D. Lehman;Claudine Isaacs;Mitchell D. Schnall;Etta D. Pisano

  • Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

    Steven A. Narod;Marie Pierre Dubé;Jan Klijn;Jan Lubinski

Frequent Co-Authors

Judy Garber
Judy Garber Harvard University
Susan M. Domchek
Susan M. Domchek University of Pennsylvania
Susan L. Neuhausen
Susan L. Neuhausen City Of Hope National Medical Center
Olufunmilayo I. Olopade
Olufunmilayo I. Olopade University of Chicago
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Mary B. Daly
Mary B. Daly Fox Chase Cancer Center
Eitan Friedman
Eitan Friedman City University of New York
Timothy R. Rebbeck
Timothy R. Rebbeck Harvard University

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