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Monica A. Gorassini

Monica A. Gorassini

D-Index & Metrics

Neuroscience

D-Index
47
Citations
8189
World Ranking
6451
National Ranking
380

Overview

Monica A. Gorassini is affiliated with the University of Alberta in Canada. Their research spans several fields and subfields within neuroscience and medicine, with a particular focus on cellular and molecular neuroscience, cognitive neuroscience, pediatrics, perinatology and child health, biomedical engineering, and psychiatry and mental health.

Their main topics of work include:

  • Neuroscience and Neuropharmacology Research
  • Muscle activation and electromyography studies
  • Transcranial Magnetic Stimulation Studies
  • Photoreceptor and optogenetics research
  • Neural dynamics and brain function
  • Cerebral Palsy and Movement Disorders
  • Spinal Cord Injury Research

Gorassini has published extensively, with notable publication venues including:

  • Journal of Neurophysiology
  • The Journal of Physiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Neuroscience
  • Frontiers in Cellular Neuroscience

Their recent significant papers include:

  • "Estimation of self-sustained activity produced by persistent inward currents using firing rate profiles of multiple motor units in humans" (2020, Journal of Neurophysiology)
  • "GABA facilitates spike propagation through branch points of sensory axons in the spinal cord" (2022, Nature Neuroscience)
  • "Post-activation depression from primary afferent depolarization (PAD) produces extensor H-reflex suppression following flexor afferent conditioning" (2023, The Journal of Physiology)
  • "Altered Motoneuron Properties Contribute to Motor Deficits in a Rabbit Hypoxia-Ischemia Model of Cerebral Palsy" (2020, Frontiers in Cellular Neuroscience)
  • "Facilitation of sensory transmission to motoneurons during cortical or sensory-evoked primary afferent depolarization (PAD) in humans" (2023, The Journal of Physiology)

Frequent collaborators in Gorassini's work include:

  • David J. Bennett
  • Babak Afsharipour
  • Katharina A. Quinlan
  • Krishnapriya Hari
  • Shihao Lin

The body of research conducted by Gorassini encompasses investigations into the neurophysiological mechanisms underlying motor control and sensory transmission. This includes studies on persistent inward currents in motor units, GABAergic facilitation in sensory axons, and the effects of primary afferent depolarization on reflex modulation. Additionally, their research addresses motor deficits in cerebral palsy models, contributing to the understanding of movement disorders.

Best Publications

  • PERSISTENT INWARD CURRENTS IN MOTONEURON DENDRITES: IMPLICATIONS FOR MOTOR OUTPUT

    C. J. Heckman;Monica A. Gorassini;David J. Bennett

  • Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors

    Katherine C Murray;Aya Nakae;Marilee J Stephens;Michelle Rank

  • Role of Persistent Sodium and Calcium Currents in Motoneuron Firing and Spasticity in Chronic Spinal Rats

    Yunru Li;Monica A. Gorassini;David J. Bennett

  • Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats

    David J. Bennett;Hans Hultborn;Brent Fedirchuk;Monica Gorassini

  • Increases in corticospinal tract function by treadmill training after incomplete spinal cord injury.

    Sarah L. Thomas;Monica A. Gorassini

  • Effects of transcranial direct current stimulation on the excitability of the leg motor cortex

    Dean T. Jeffery;Jonathan A. Norton;Francois D. Roy;Monica A. Gorassini

  • Role of motoneurons in the generation of muscle spasms after spinal cord injury

    Monica A. Gorassini;Michael E. Knash;Philip J. Harvey;Dave J. Bennett

  • Evidence for plateau potentials in tail motoneurons of awake chronic spinal rats with spasticity.

    David J. Bennett;Yunru Li;Philip J. Harvey;Monica Gorassini

  • Intrinsic Activation of Human Motoneurons: Possible Contribution to Motor Unit Excitation

    Monica Gorassini;Jaynie F. Yang;Merek Siu;David J. Bennett

  • Spinal and Brain Control of Human Walking: Implications for Retraining of Walking:

    Jaynie F. Yang;Monica Gorassini

  • Spasticity in rats with sacral spinal cord injury.

    D. J. Bennett;M. Gorassini;K. Fouad;L. Sanelli

  • Spastic long-lasting reflexes in the awake rat after sacral spinal cord injury.

    D. J. Bennett;L. Sanelli;C. L. Cooke;P. J. Harvey

  • Models of ensemble firing of muscle spindle afferents recorded during normal locomotion in cats

    Arthur Prochazka;Monica Gorassini

  • Self-sustained firing of human motor units

    Monica A Gorassini;David J Bennett;Jaynie F Yang

  • Ensemble firing of muscle afferents recorded during normal locomotion in cats

    Arthur Prochazka;Monica Gorassini

  • Changes in Cortically Related Intermuscular Coherence Accompanying Improvements in Locomotor Skills in Incomplete Spinal Cord Injury

    Jonathan A. Norton;Monica A. Gorassini

  • Intrinsic Activation of Human Motoneurons: Reduction of Motor Unit Recruitment Thresholds by Repeated Contractions

    Monica Gorassini;Jaynie F. Yang;Merek Siu;David J. Bennett

  • Corrective responses to loss of ground support during walking. I: Intact cats

    Monica A. Gorassini;Arthur Prochazka;Gordon W. Hiebert;Michael J. A. Gauthier

  • Recovery of neuronal and network excitability after spinal cord injury and implications for spasticity.

    Jessica M. D'Amico;Elizabeth G. Condliffe;Karen J. B. Martins;David J. Bennett

  • Corrective responses to loss of ground support during walking. II. Comparison of intact and chronic spinal cats

    Gordon W. Hiebert;Monica A. Gorassini;Wan Jiang;Arthur Prochazka

  • Safety and tolerability of transcranial magnetic and direct current stimulation in children: Prospective single center evidence from 3.5 million stimulations.

    E. Zewdie;P. Ciechanski;H.C. Kuo;A. Giuffre

Frequent Co-Authors

David J. Bennett
David J. Bennett University of Alberta
Jaynie F. Yang
Jaynie F. Yang University of Alberta
Arthur Prochazka
Arthur Prochazka University of Alberta
Karim Fouad
Karim Fouad University of Alberta
Hans Hultborn
Hans Hultborn University of Copenhagen
Kemal S. Türker
Kemal S. Türker Istanbul Gelişim University
Adam Kirton
Adam Kirton University of Calgary
Charles J. Heckman
Charles J. Heckman Northwestern University
Monica A. Perez
Monica A. Perez Shirley Ryan AbilityLab
David F. Collins
David F. Collins University of Alberta

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