World's Best Scientists 2026 revealed!
J. Troy Littleton

J. Troy Littleton

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
15221
World Ranking
13633
National Ranking
5785

J. Troy Littleton publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where J. Troy Littleton sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 150 publications — 27th percentile

27% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

J. Troy Littleton D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where J. Troy Littleton sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 57 D-Index — 31st percentile

31% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2001 - Fellow of Alfred P. Sloan Foundation

Overview

J. Troy Littleton is affiliated with MIT in the United States. Their research spans several fields and subfields within biological sciences, primarily focused on neuroscience and molecular biology. Littleton has made considerable contributions in main fields including Biochemistry, Genetics and Molecular Biology, and Neuroscience. The subfields of study pertinent to their work include Cellular and Molecular Neuroscience, Molecular Biology, Cell Biology, Genetics, and Ecology.

Their research topics cover a diverse range of areas with an emphasis on neurobiological and physiological processes, specifically related to insect models. Key topics in their work are:

  • Neurobiology and Insect Physiology Research
  • Cellular transport and secretion
  • Neuroscience and Neuropharmacology Research
  • Lipid Membrane Structure and Behavior
  • Insect and Arachnid Ecology and Behavior
  • Physiological and biochemical adaptations
  • Retinal Development and Disorders

Littleton's recent published papers illustrate their focus on synaptic plasticity, neuronal function, and synaptic vesicle biology. Notable recent papers include:

  • Synaptic Plasticity Induced by Differential Manipulation of Tonic and Phasic Motoneurons in Drosophila (2020), Journal of Neuroscience
  • SNARE Regulatory Proteins in Synaptic Vesicle Fusion and Recycling (2021), Frontiers in Molecular Neuroscience
  • Synaptic Properties and Plasticity Mechanisms of Invertebrate Tonic and Phasic Neurons (2020), Frontiers in Physiology
  • Molecular logic of synaptic diversity between Drosophila tonic and phasic motoneurons (2023), Neuron
  • Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner (2020), eLife

Their frequent collaborators include Yulia Akbergenova, Karen L Cunningham, Nicole A. Aponte-Santiago, Kiel G. Ormerod, and Suresh Kumar Jetti. These coauthors have contributed alongside Littleton on multiple publications, reflecting ongoing collaborative research efforts.

J. Troy Littleton's work has appeared frequently in several scientific venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Journal of Neuroscience
  • Frontiers in Molecular Neuroscience

In 2001, Littleton was recognized as a Fellow of the Alfred P. Sloan Foundation, an award indicating their established presence in the scientific community.

Best Publications

  • Comparative Genomics of the Eukaryotes

    Gerald M. Rubin;Mark D. Yandell;Jennifer R. Wortman;George L. Gabor

  • Insights into social insects from the genome of the honeybee Apis mellifera

    George M. Weinstock;Gene E. Robinson;Richard A. Gibbs;Kim C. Worley

  • Ion channels and synaptic organization: analysis of the Drosophila genome.

    J.Troy Littleton;J.Troy Littleton;Barry Ganetzky

  • Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca2+-activated neurotransmitter release

    J.Troy Littleton;Michael Stern;Karen Schulze;Mark Perin

  • A Drosophila Neurexin Is Required for Septate Junction and Blood-Nerve Barrier Formation and Function

    Stefan Baumgartner;J.Troy Littleton;Kendal Broadie;Manzoor A Bhat

  • Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

    Wyan-Ching Mimi Lee;Motojiro Yoshihara;J. Troy Littleton

  • Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants

    J T Littleton;M Stern;M Perin;H J Bellen

  • Synaptotagmin I Functions as a Calcium Sensor to Synchronize Neurotransmitter Release

    Motojiro Yoshihara;J.Troy Littleton

  • A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth.

    Sarah Huntwork;J Troy Littleton

  • Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse

    J.T. Littleton;H.J. Bellen;M.S. Perin

  • Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission

    K Broadie;H J Bellen;A DiAntonio;J T Littleton

  • Temperature-Sensitive Paralytic Mutations Demonstrate that Synaptic Exocytosis Requires SNARE Complex Assembly and Disassembly

    J.Troy Littleton;Edwin R Chapman;Robert Kreber;Martin B Garment

  • ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner.

    Mark N. Wu;J. Troy Littleton;Manzoor A. Bhat;Andreas Prokop

  • Transmission, Development, and Plasticity of Synapses

    Kathryn P. Harris;J. Troy Littleton

  • synaptotagmin Mutants Reveal Essential Functions for the C2B Domain in Ca2+-Triggered Fusion and Recycling of Synaptic Vesicles In Vivo

    J. Troy Littleton;Jihong Bai;Bimal Vyas;Radhika Desai

  • rop, a Drosophila homolog of yeast Sec1 and vertebrate n-Sec1/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo.

    K Schulze;J T Littleton;A Salzberg;N Halachmi

  • Spontaneous and Evoked Release Are Independently Regulated at Individual Active Zones

    Jan Elizabeth Melom;Yulia Akbergenova;Jeffrey Gavornik;J. Troy Littleton

  • Retrograde Signaling by Syt 4 Induces Presynaptic Release and Synapse-Specific Growth

    Motojiro Yoshihara;Bill Adolfsen;Kathleen T. Galle;J. Troy Littleton

  • The biological function of the Huntingtin protein and its relevance to Huntington's Disease pathology.

    Joost Schulte;J. Troy Littleton

  • Synaptotagmin controls and modulates synaptic-vesicle fusion in a Ca2+-dependent manner

    J. Troy Littleton;Hugo J. Bellen

Frequent Co-Authors

Hugo J. Bellen
Hugo J. Bellen Baylor College of Medicine
Barry Ganetzky
Barry Ganetzky University of Wisconsin–Madison
Edwin R. Chapman
Edwin R. Chapman University of Wisconsin–Madison
Norbert Perrimon
Norbert Perrimon Harvard University
Hanns Lochmüller
Hanns Lochmüller University of Freiburg
Xiaowei Zhuang
Xiaowei Zhuang Harvard University
Rita Horvath
Rita Horvath University of Cambridge
Stephan Züchner
Stephan Züchner University of Miami
Patrick F. Chinnery
Patrick F. Chinnery University of Cambridge
Richard A. Gibbs
Richard A. Gibbs Baylor College of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing J. Troy Littleton

Trending Scientists

Recently Published Articles