World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
60
Citations
11954
World Ranking
3150
National Ranking
1247

Research.com Recognitions

  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Raymond P. Roos is affiliated with the University of Chicago in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, along with Medicine. Within these areas, their focus includes Molecular Biology, Neurology, Genetics, Cellular and Molecular Neuroscience, and Physiology.

The scientist's work concentrates on topics such as Amyotrophic Lateral Sclerosis Research, RNA Research and Splicing, Neurogenetic and Muscular Disorders Research, RNA and protein synthesis mechanisms, Fungal and yeast genetics research, RNA modifications and cancer, and Mitochondrial Function and Pathology.

Roos has authored several recent papers, including:

  • A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation, 2021, Nature Communications
  • Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions, 2022, PLoS ONE
  • RNA-binding protein altered expression and mislocalization in MS, 2020, Neurology Neuroimmunology & Neuroinflammation
  • Kozak Similarity Score Algorithm Identifies Alternative Translation Initiation Codons Implicated in Cancers, 2022, International Journal of Molecular Sciences
  • Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons, 2023, eLife

The scientist frequently collaborates with a number of co-authors, including:

  • Yoshifumi Sonobe
  • Ghanashyam D. Ghadge
  • Paschalis Kratsios
  • Alec C. Gleason
  • Gopinath Krishnan

Roos's publications have appeared in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • JAMA
  • Neurology
  • Nature Communications
  • PLoS ONE

In recognition of their scientific contributions, Roos was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2004.

Best Publications

  • Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

    Han Xiang Deng;Afif Hentati;John A. Tainer;Zafar Iqbal

  • TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

    Ian R. Mackenzie;Alexandra M. Nicholson;Mohona Sarkar;James Messing

  • Mutant Superoxide Dismutase-1-Linked Familial Amyotrophic Lateral Sclerosis: Molecular Mechanisms of Neuronal Death and Protection

    G. D. Ghadge;J. P. Lee;V. P. Bindokas;J. Jordan

  • Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice

    Lijun Wang;David H. Gutmann;Raymond P. Roos

  • p53 Expression Induces Apoptosis in Hippocampal Pyramidal Neuron Cultures

    Joaquı́n Jordán;Marı́a F. Galindo;Jochen H. M. Prehn;Ralph R. Weichselbaum

  • Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons.

    Jochen H M Prehn;Vytautas P. Bindokas;Joaquín Jordán;María F. Galindo

  • Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.

    Conrad C. Weihl;Ghanashyam D. Ghadge;Scott G. Kennedy;Nissim Hay

  • CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses.

    G D Ghadge;R P Roos;U J Kang;R Wollmann

  • The Unfolded Protein Response in Familial Amyotrophic Lateral Sclerosis

    Lijun Wang;Brian Popko;Raymond P. Roos

  • Molecular cloning and sequence determination of DA strain of Theiler's murine encephalomyelitis viruses

    Yoshiro Ohara;Steven Stein;Jianlin Fu;Linda Stillman

  • Isoelectric focusing of IgG eluted from multiple sclerosis and subacute sclerosing panencephalitis brains

    David H. Mattson;Raymond P. Roos;Barry G. W. Arnason

  • Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis.

    Lijun Wang;Brian Popko;Emily Tixier;Raymond P. Roos

  • Ca2+ and reactive oxygen species in staurosporine-induced neuronal apoptosis

    J. H. M. Prehn;J. Jordán;G. D. Ghadge;E. Preis

  • Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models

    Ghanashyam D. Ghadge;Barbara S. Slusher;Amos Bodner;Mauro Dal Canto

  • Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse

    Lijun Wang;Han-Xiang Deng;Gabriella Grisotti;Hong Zhai

  • Cell-specific proteins regulate viral RNA translation and virus-induced disease

    Evgeny V. Pilipenko;Ekaterina G. Viktorova;Stephen T. Guest;Vadim I. Agol;Vadim I. Agol

  • The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis.

    Lijun Wang;Kamal Sharma;Gabriella Grisotti;Raymond P. Roos

  • Regulation of excitatory transmission at hippocampal synapses by calbindin D28k

    Paul S. Chard;Joaquin Jordan;Charles J. Marcuccilli;Richard J. Miller

  • An enhanced integrated stress response ameliorates mutant SOD1-induced ALS

    Lijun Wang;Brian Popko;Raymond P. Roos

  • Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress.

    Yoshifumi Sonobe;Ghanashyam Ghadge;Katsuhisa Masaki;Ataman Sendoel

  • The effect of short-term and chronic immunosuppression on Theiler's virus demyelination☆

    Raymond P. Roos;Susan Firestone;Robert Wollmann;Daina Variakojis

Frequent Co-Authors

Richard J. Miller
Richard J. Miller Northwestern University
Jack P. Antel
Jack P. Antel McGill University
Barry G. W. Arnason
Barry G. W. Arnason University of Chicago
Moses Rodriguez
Moses Rodriguez Mayo Clinic
Teepu Siddique
Teepu Siddique Northwestern University
Conrad C. Weihl
Conrad C. Weihl Washington University in St. Louis
Joaquín Jordán
Joaquín Jordán University of Castilla-La Mancha
Brian Popko
Brian Popko Northwestern University
Jochen H. M. Prehn
Jochen H. M. Prehn Royal College of Surgeons in Ireland
Neil R. Cashman
Neil R. Cashman University of British Columbia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in microbiology, exploring related online degrees can open diverse career pathways in healthcare and science. Fields such as health information management not only complement microbiology knowledge but also offer strong job prospects. Those wondering about compensation can find valuable insights by looking into health information management jobs salary, which reflects competitive earnings in this sector.

Enrolling in accredited programs is crucial for quality education and career advancement. For those keen on online study options, discovering the best online cahiim accredited health information management degree programs provides a reliable pathway to gaining recognized credentials.

Additionally, some professionals may opt for specialized certificates such as medical billing and coding. These can typically be completed faster than traditional degrees, making them attractive for quick career entry. Information on the online medical billing and coding certificate fast options can help prospective students find accelerated paths.

Lastly, for those exploring medical careers broadly, it’s helpful to understand what medical degree can i get online. This knowledge supports informed decision-making when combining microbiology expertise with healthcare education through flexible online formats.

Best Scientists Citing Raymond P. Roos

Trending Scientists

Recently Published Articles