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Bradley L. Pentelute

Bradley L. Pentelute

D-Index & Metrics

Chemistry

D-Index
43
Citations
8187
World Ranking
17113
National Ranking
4211

Overview

Bradley L. Pentelute is affiliated with MIT in the United States and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research spans several subfields, including Molecular Biology, Radiology, Nuclear Medicine and Imaging, Organic Chemistry, Oncology, and Immunology.

Their work covers diverse topics such as Chemical Synthesis and Analysis, Advanced biosensing and bioanalysis techniques, Monoclonal and Polyclonal Antibodies Research, Click Chemistry and Applications, RNA Interference and Gene Delivery, vaccines and immunoinformatics approaches, and Antimicrobial Peptides and Activities.

Examples of recent papers by Bradley L. Pentelute include:

  • Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma, 2021, Nature Medicine
  • Synthesis of proteins by automated flow chemistry, 2020, Science
  • Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Ultra-large chemical libraries for the discovery of high-affinity peptide binders, 2020, Nature Communications
  • Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein, 2021, PLoS ONE

Frequent co-authors collaborating with Pentelute are:

  • Andrei Loas
  • Carly K. Schissel
  • Charlotte E. Farquhar
  • Stephen L. Buchwald
  • Nina Hartrampf

Bradley L. Pentelute has published regularly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Chemical Society
  • ACS Central Science
  • ACS Chemical Biology
  • Chemical Science

Best Publications

  • Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

    Basil P. Hubbard;Ana P. Gomes;Ana P. Gomes;Han Dai;Jun Li

  • A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling

    Alexander M. Spokoyny;Yekui Zou;Jingjing J. Ling;Hongtao Yu

  • Organometallic palladium reagents for cysteine bioconjugation

    Ekaterina V. Vinogradova;Chi Zhang;Alexander M. Spokoyny;Bradley L. Pentelute

  • Synthesis of Proteins by Automated Flow Chemistry

    N. Hartrampf;A. Saebi;M. Poskus;Z. P. Gates

  • A fully automated flow-based approach for accelerated peptide synthesis.

    Alexander J Mijalis;Dale A Thomas;Mark D Simon;Andrea Adamo

  • Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.

    Choi-Fong Cho;Choi-Fong Cho;Justin M. Wolfe;Colin M. Fadzen;David Calligaris

  • π-Clamp-mediated cysteine conjugation

    Chi Zhang;Matthew Welborn;Tianyu Zhu;Nicole J. Yang

  • Atomic structure of anthrax protective antigen pore elucidates toxin translocation

    Jiansen Jiang;Bradley L. Pentelute;R. John Collier;Z. Hong Zhou

  • Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

    Sonja Bergmann;Sean E. Lawler;Yuan Qu;Colin M. Fadzen

  • Arylation Chemistry for Bioconjugation.

    Chi Zhang;Ekaterina V. Vinogradova;Ekaterina V. Vinogradova;Alexander M. Spokoyny;Alexander M. Spokoyny;Stephen L. Buchwald

  • Affinity-based capture and identification of protein effectors of the growth regulator ppGpp.

    Boyuan Wang;Peng Dai;David Ding;Amanda Del Rosario

  • Rapid Flow-Based Peptide Synthesis

    Mark D. Simon;Patrick L. Heider;Andrea Adamo;Alexander A. Vinogradov

  • Ultra-large chemical libraries for the discovery of high-affinity peptide binders

    Anthony James Quartararo;Zachary P Gates;Bente A. Somsen;Nina Hartrampf

  • Ultra-large chemical libraries for the discovery of high-affinity peptide binders.

    Anthony J. Quartararo;Zachary P. Gates;Bente A. Somsen;Nina Hartrampf

  • Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD

    Genwei Zhang;Sebastian Pomplun;Alexander Robert Loftis;Xuyu Tan

  • Palladium-Mediated Arylation of Lysine in Unprotected Peptides.

    Hong Geun Lee;Guillaume Lautrette;Bradley L. Pentelute;Stephen L. Buchwald

  • Nitrogen Arylation for Macrocyclization of Unprotected Peptides

    Guillaume Lautrette;Fayçal Touti;Hong Geun Lee;Peng Dai

  • Cholesterol-binding site of the influenza M2 protein in lipid bilayers from solid-state NMR

    Matthew R Elkins;Jonathan K Williams;Martin D Gelenter;Peng Dai

  • Palladium Oxidative Addition Complexes for Peptide and Protein Cross-linking.

    Koji Kubota;Peng Dai;Bradley L. Pentelute;Stephen L. Buchwald

  • Systematic Investigation of EDC/sNHS-Mediated Bioconjugation Reactions for Carboxylated Peptide Substrates.

    Kyle A. Totaro;Xiaoli Liao;Keshab Bhattacharya;Jari I. Finneman

  • Divergent unprotected peptide macrocyclisation by palladium-mediated cysteine arylation

    Anthony J. Rojas;Chi Zhang;Ekaterina V. Vinogradova;Nathan H. Buchwald

  • Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

    B. P. Hubbard;A. P. Gomes;H. Dai;J. Li

  • Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

    David Calligaris;Kalvis Hornburg;E. Antonio Chiocca;Nathalie Y. R. Agar

Frequent Co-Authors

Alexander M. Spokoyny
Alexander M. Spokoyny University of California, Los Angeles
Sean E. Lawler
Sean E. Lawler Brown University
E. Antonio Chiocca
E. Antonio Chiocca Brigham and Women's Hospital
R. John Collier
R. John Collier Harvard University
Darrell J. Irvine
Darrell J. Irvine Scripps Research Institute
Deborah T. Hung
Deborah T. Hung Harvard University
Nir Hacohen
Nir Hacohen Harvard University

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