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D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
61740
World Ranking
2054
National Ranking
1121

Overview

J. Paul Taylor is affiliated with St. Jude Children's Research Hospital in the United States. Their research spans multiple fields with a focus on biochemistry, genetics, and molecular biology, contributing notably to medicine as well. Their work is highly concentrated in molecular biology, neurology, cell biology, genetics, and cellular and molecular neuroscience.

The main research topics addressed by J. Paul Taylor include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • RNA and protein synthesis mechanisms
  • Endoplasmic Reticulum Stress and Disease
  • Cancer Genomics and Diagnostics

The scientist has frequently published in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Cell Reports
  • Nature Communications
  • Cell

Frequent coauthors in J. Paul Taylor's publications include:

  • Hong Joo Kim
  • James Messing
  • Brian D. Freibaum
  • Yong-Dong Wang
  • Peiguo Yang

Among J. Paul Taylor's recent papers are:

  • G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules, 2020, Cell
  • Beyond aggregation: Pathological phase transitions in neurodegenerative disease, 2020, Science
  • Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner, 2021, Science
  • Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency, 2020, Nature
  • Validation of serum neurofilaments as prognostic and potential pharmacodynamic biomarkers for ALS, 2020, Neurology

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

    Amandine Molliex;Jamshid Temirov;Jihun Lee;Maura Coughlin

  • Decoding ALS: from genes to mechanism

    J. Paul Taylor;Robert H. Brown;Don W. Cleveland;Don W. Cleveland

  • Toxic proteins in neurodegenerative disease.

    J. Paul Taylor;John Hardy;Kenneth H. Fischbeck

  • Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

    Hong Joo Kim;Nam Chul Kim;Yong Dong Wang;Emily A. Scarborough

  • Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

    Janel O. Johnson;Jessica Mandrioli;Michael Benatar;Yevgeniya Abramzon

  • HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

    Udai Bhan Pandey;Zhiping Nie;Yakup Batlevi;Brett A. McCray

  • GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

    Brian D. Freibaum;Yubing Lu;Rodrigo Lopez-Gonzalez;Nam Chul Kim

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

    Peiguo Yang;Cécile Mathieu;Cécile Mathieu;Regina-Maria Kolaitis;Peipei Zhang

  • Tau protein liquid–liquid phase separation can initiate tau aggregation

    Susanne Wegmann;Bahareh Eftekharzadeh;Katharina Tepper;Katarzyna M Zoltowska

  • HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

    Joo Yong Lee;Hiroshi Koga;Yoshiharu Kawaguchi;Waixing Tang

  • Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

    J. Ross Buchan;Regina Maria Kolaitis;J. Paul Taylor;Roy Parker

  • CREB-binding protein sequestration by expanded polyglutamine

    Alexander McCampbell;J. Paul Taylor;Addis A. Taye;Jon Robitschek

  • C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.

    Kyung Ha Lee;Peipei Zhang;Hong Joo Kim;Diana M. Mitrea

  • Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

    Nael H. Alami;Rebecca B. Smith;Monica A. Carrasco;Luis A. Williams

  • Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders

    Mani Ramaswami;J. Paul Taylor;Roy Parker

  • Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

    Joo-Yong Lee;Yoshito Nagano;J. Paul Taylor;Kah Leong Lim

Frequent Co-Authors

Kenneth H. Fischbeck
Kenneth H. Fischbeck National Institutes of Health
Bryan J. Traynor
Bryan J. Traynor National Institutes of Health
Albert R. La Spada
Albert R. La Spada University of California, Irvine
Joanne Wuu
Joanne Wuu University of Miami
Rosa Rademakers
Rosa Rademakers University of Antwerp
Gang Wu
Gang Wu Washington University in St. Louis
Conrad C. Weihl
Conrad C. Weihl Washington University in St. Louis
Tso-Pang Yao
Tso-Pang Yao Duke University
Aaron D. Gitler
Aaron D. Gitler Stanford University
Christopher Shaw
Christopher Shaw King's College London

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