D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 5,834 111 World Ranking 15909 National Ranking 6607

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Apoptosis

Hansoo Lee focuses on Cell biology, Protein kinase B, Cancer research, Signal transduction and Angiogenesis. His research in Cell biology intersects with topics in Vascular endothelial growth factor and Nitric oxide. His Protein kinase B study integrates concerns from other disciplines, such as NADPH oxidase and PI3K/AKT/mTOR pathway.

His Cancer research research is multidisciplinary, relying on both Tetraspanin and c-jun. Hansoo Lee interconnects Cancer cell and Transfection in the investigation of issues within Signal transduction. He has researched Angiogenesis in several fields, including Vascular endothelial growth factor A, Tube formation, Enos and MAPK/ERK pathway.

His most cited work include:

  • SIRT1 promotes DNA repair activity and deacetylation of Ku70. (247 citations)
  • The non-provitamin A carotenoid, lutein, inhibits NF-κB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-κB-inducing kinase pathways: Role of H2O2 in NF-κB activation (179 citations)
  • β-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-κB activation (173 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Cancer research, Angiogenesis, Molecular biology and Protein kinase B. His Cell biology research is multidisciplinary, incorporating elements of Integrin and Cell adhesion. His work carried out in the field of Cancer research brings together such families of science as Cancer cell, Cancer, Inflammation, Motility and Metastasis suppressor.

Hansoo Lee has included themes like Endothelial stem cell, Tube formation, Vascular endothelial growth factor, Enos and Nitric oxide in his Angiogenesis study. In Molecular biology, Hansoo Lee works on issues like Downregulation and upregulation, which are connected to Endothelial dysfunction. His Protein kinase B research integrates issues from Mitogen-activated protein kinase and MAPK/ERK pathway.

He most often published in these fields:

  • Cell biology (49.57%)
  • Cancer research (50.43%)
  • Angiogenesis (28.70%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (50.43%)
  • Cell biology (49.57%)
  • Cancer cell (21.74%)

In recent papers he was focusing on the following fields of study:

Hansoo Lee mostly deals with Cancer research, Cell biology, Cancer cell, Angiogenesis and Immunology. His research integrates issues of Endothelial stem cell, Metastasis and Cell growth in his study of Cancer research. His work deals with themes such as Molecular biology and Cell adhesion, which intersect with Cell biology.

His research investigates the connection between Cancer cell and topics such as Epithelial–mesenchymal transition that intersect with problems in Transactivation, Transfection, GSK-3 and Wnt signaling pathway. His Angiogenesis study combines topics in areas such as Tumor necrosis factor alpha, Inflammation, Enos, Vascular permeability and Endothelial dysfunction. His biological study deals with issues like Cytokine, which deal with fields such as Signal transduction.

Between 2015 and 2021, his most popular works were:

  • Aspirin prevents TNF-α-induced endothelial cell dysfunction by regulating the NF-κB-dependent miR-155/eNOS pathway: Role of a miR-155/eNOS axis in preeclampsia. (58 citations)
  • NF-κB–responsive miRNA-31-5p elicits endothelial dysfunction associated with preeclampsia via down-regulation of endothelial nitric-oxide synthase (24 citations)
  • Carbon Monoxide Potentiation of L-Type Ca2+ Channel Activity Increases HIF-1α-Independent VEGF Expression via an AMPKα/SIRT1-Mediated PGC-1α/ERRα Axis. (22 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Apoptosis

His primary areas of investigation include Cell biology, Endothelial dysfunction, Enos, Angiogenesis and Tumor necrosis factor alpha. In his study, which falls under the umbrella issue of Cell biology, Mitochondrial ROS is strongly linked to Molecular biology. His Endothelial dysfunction study also includes

  • Proinflammatory cytokine that intertwine with fields like Cancer research,
  • Endothelial stem cell which intersects with area such as Downregulation and upregulation.

The various areas that Hansoo Lee examines in his Cancer research study include Epithelial–mesenchymal transition, Cancer cell, Cancer, Prostate cancer and Fibronectin. He combines subjects such as Cytochrome and Mitochondrial respiratory chain with his study of Cytochrome c. His Protein kinase A research incorporates themes from Vascular endothelial growth factor A and Vascular endothelial growth factor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

SIRT1 promotes DNA repair activity and deacetylation of Ku70.

Jaemin Jeong;Kyungmi Juhn;Hansoo Lee;Sang Hoon Kim.
Experimental and Molecular Medicine (2007)

376 Citations

The non-provitamin A carotenoid, lutein, inhibits NF-κB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-κB-inducing kinase pathways: Role of H2O2 in NF-κB activation

Ji Hee Kim;Hee Jun Na;Chun Ki Kim;Ji Yoon Kim.
Free Radical Biology and Medicine (2008)

304 Citations

β-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-κB activation

Se Kyung Bai;Seon Jin Lee;Hee Jun Na;Kwon Soo Ha.
Experimental and Molecular Medicine (2005)

271 Citations

Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways.

Seon Jin Lee;Seung Namkoong;Young Mi Kim;Chun Ki Kim.
American Journal of Physiology-heart and Circulatory Physiology (2006)

202 Citations

Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma.

Bomsoo Cho;Hansoo Lee;Shin Wu Jeong;Yung Jue Bang.
Biochemical and Biophysical Research Communications (2003)

183 Citations

CD44-Epidermal Growth Factor Receptor Interaction Mediates Hyaluronic Acid-promoted Cell Motility by Activating Protein Kinase C Signaling Involving Akt, Rac1, Phox, Reactive Oxygen Species, Focal Adhesion Kinase, and MMP-2

Youngmi Kim;Yun Sil Lee;Jongseon Choe;Hansoo Lee.
Journal of Biological Chemistry (2008)

180 Citations

Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells.

Byung Hee Chung;Jong Dai Kim;Chun Ki Kim;Jung Whan Kim.
Biochemical and Biophysical Research Communications (2008)

179 Citations

Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells.

Seung Namkoong;Seon Jin Lee;Chun Ki Kim;Young Mi Kim.
Experimental and Molecular Medicine (2005)

166 Citations

Carbon Monoxide Promotes VEGF Expression by Increasing HIF-1α Protein Level via Two Distinct Mechanisms, Translational Activation and Stabilization of HIF-1α Protein

Yoon Kyung Choi;Chun Ki Kim;Hansoo Lee;Dooil Jeoung.
Journal of Biological Chemistry (2010)

157 Citations

A Splice Variant of CD99 Increases Motility and MMP-9 Expression of Human Breast Cancer Cells through the AKT-, ERK-, and JNK-dependent AP-1 Activation Signaling Pathways

Hee-Jung Byun;In-Kee Hong;In-Kee Hong;Eunsook Kim;Eunsook Kim;Young-June Jin;Young-June Jin.
Journal of Biological Chemistry (2006)

146 Citations

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