Hansoo Lee focuses on Cell biology, Protein kinase B, Cancer research, Signal transduction and Angiogenesis. His research in Cell biology intersects with topics in Vascular endothelial growth factor and Nitric oxide. His Protein kinase B study integrates concerns from other disciplines, such as NADPH oxidase and PI3K/AKT/mTOR pathway.
His Cancer research research is multidisciplinary, relying on both Tetraspanin and c-jun. Hansoo Lee interconnects Cancer cell and Transfection in the investigation of issues within Signal transduction. He has researched Angiogenesis in several fields, including Vascular endothelial growth factor A, Tube formation, Enos and MAPK/ERK pathway.
The scientist’s investigation covers issues in Cell biology, Cancer research, Angiogenesis, Molecular biology and Protein kinase B. His Cell biology research is multidisciplinary, incorporating elements of Integrin and Cell adhesion. His work carried out in the field of Cancer research brings together such families of science as Cancer cell, Cancer, Inflammation, Motility and Metastasis suppressor.
Hansoo Lee has included themes like Endothelial stem cell, Tube formation, Vascular endothelial growth factor, Enos and Nitric oxide in his Angiogenesis study. In Molecular biology, Hansoo Lee works on issues like Downregulation and upregulation, which are connected to Endothelial dysfunction. His Protein kinase B research integrates issues from Mitogen-activated protein kinase and MAPK/ERK pathway.
Hansoo Lee mostly deals with Cancer research, Cell biology, Cancer cell, Angiogenesis and Immunology. His research integrates issues of Endothelial stem cell, Metastasis and Cell growth in his study of Cancer research. His work deals with themes such as Molecular biology and Cell adhesion, which intersect with Cell biology.
His research investigates the connection between Cancer cell and topics such as Epithelial–mesenchymal transition that intersect with problems in Transactivation, Transfection, GSK-3 and Wnt signaling pathway. His Angiogenesis study combines topics in areas such as Tumor necrosis factor alpha, Inflammation, Enos, Vascular permeability and Endothelial dysfunction. His biological study deals with issues like Cytokine, which deal with fields such as Signal transduction.
His primary areas of investigation include Cell biology, Endothelial dysfunction, Enos, Angiogenesis and Tumor necrosis factor alpha. In his study, which falls under the umbrella issue of Cell biology, Mitochondrial ROS is strongly linked to Molecular biology. His Endothelial dysfunction study also includes
The various areas that Hansoo Lee examines in his Cancer research study include Epithelial–mesenchymal transition, Cancer cell, Cancer, Prostate cancer and Fibronectin. He combines subjects such as Cytochrome and Mitochondrial respiratory chain with his study of Cytochrome c. His Protein kinase A research incorporates themes from Vascular endothelial growth factor A and Vascular endothelial growth factor.
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SIRT1 promotes DNA repair activity and deacetylation of Ku70.
Jaemin Jeong;Kyungmi Juhn;Hansoo Lee;Sang Hoon Kim.
Experimental and Molecular Medicine (2007)
The non-provitamin A carotenoid, lutein, inhibits NF-κB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-κB-inducing kinase pathways: Role of H2O2 in NF-κB activation
Ji Hee Kim;Hee Jun Na;Chun Ki Kim;Ji Yoon Kim.
Free Radical Biology and Medicine (2008)
β-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-κB activation
Se Kyung Bai;Seon Jin Lee;Hee Jun Na;Kwon Soo Ha.
Experimental and Molecular Medicine (2005)
Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways.
Seon Jin Lee;Seung Namkoong;Young Mi Kim;Chun Ki Kim.
American Journal of Physiology-heart and Circulatory Physiology (2006)
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma.
Bomsoo Cho;Hansoo Lee;Shin Wu Jeong;Yung Jue Bang.
Biochemical and Biophysical Research Communications (2003)
CD44-Epidermal Growth Factor Receptor Interaction Mediates Hyaluronic Acid-promoted Cell Motility by Activating Protein Kinase C Signaling Involving Akt, Rac1, Phox, Reactive Oxygen Species, Focal Adhesion Kinase, and MMP-2
Youngmi Kim;Yun Sil Lee;Jongseon Choe;Hansoo Lee.
Journal of Biological Chemistry (2008)
Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells.
Byung Hee Chung;Jong Dai Kim;Chun Ki Kim;Jung Whan Kim.
Biochemical and Biophysical Research Communications (2008)
Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells.
Seung Namkoong;Seon Jin Lee;Chun Ki Kim;Young Mi Kim.
Experimental and Molecular Medicine (2005)
Carbon Monoxide Promotes VEGF Expression by Increasing HIF-1α Protein Level via Two Distinct Mechanisms, Translational Activation and Stabilization of HIF-1α Protein
Yoon Kyung Choi;Chun Ki Kim;Hansoo Lee;Dooil Jeoung.
Journal of Biological Chemistry (2010)
A Splice Variant of CD99 Increases Motility and MMP-9 Expression of Human Breast Cancer Cells through the AKT-, ERK-, and JNK-dependent AP-1 Activation Signaling Pathways
Hee-Jung Byun;In-Kee Hong;In-Kee Hong;Eunsook Kim;Eunsook Kim;Young-June Jin;Young-June Jin.
Journal of Biological Chemistry (2006)
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