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Medicine

D-Index
104
Citations
43945
World Ranking
7005
National Ranking
3681

Overview

Patricia S. Steeg is affiliated with the National Institutes of Health in the United States. Their research spans several fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology. Their work is especially concentrated in subfields such as pulmonary and respiratory medicine, molecular biology, oncology, genetics, and neurology.

The scientist's research topics include brain metastases and treatment, glioma diagnosis and treatment, mechanisms of cancer metastasis, lung cancer research studies, lung cancer treatments and mutations, barrier structure and function studies, and nanoplatforms for cancer theranostics.

Patricia S. Steeg has published extensively, with notable papers including:

  • The blood-tumour barrier in cancer biology and therapy, 2021, Nature Reviews Clinical Oncology
  • Endocytosis: a pivotal pathway for regulating metastasis, 2020, British Journal of Cancer
  • Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines, 2020, Cancer Research
  • Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer, 2020, Oncogene
  • HER2 antibody-drug conjugate controls growth of breast cancer brain metastases in hematogenous xenograft models, with heterogeneous blood-tumor barrier penetration unlinked to a passive marker, 2020, Neuro-Oncology

Their frequent co-authors include Imran Khan, Brunilde Gril, Simone Difilippantonio, Priscilla K. Brastianos, and Debbie Wei. Collaborative work with these researchers has contributed to a number of publications and helped define much of the scientist's scholarly output.

Patricia S. Steeg's publications often appear in venues that emphasize oncology and metastasis research. The most frequent publication venues are:

  • Neuro-Oncology Advances
  • Cancer Research
  • Clinical & Experimental Metastasis
  • The Lancet Oncology
  • Neuro-Oncology

Best Publications

  • Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation.

    Lance A Liotta;Patricia S Steeg;William G Stetler-Stevenson

  • Tumor metastasis: mechanistic insights and clinical challenges

    Patricia S Steeg

  • Evidence for a Novel Gene Associated With Low Tumor Metastatic Potential

    Patricia S. Steeg;Generoso Bevilacqua;Laszlo Kopper;Unnur P. Thorgeirsson

  • Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

    Lin Zhang;Siyuan Zhang;Siyuan Zhang;Jun Yao;Frank J. Lowery

  • CNS Metastases in Breast Cancer: Old Challenge, New Frontiers

    Nancy U. Lin;Laleh Amiri-Kordestani;Diane Palmieri;David J. Liewehr

  • Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm3-transfected melanoma cells

    Alvaro Leone;Ursula Flatow;C.Richter King;Mary Ann Sandeen

  • Metastasis suppressors alter the signal transduction of cancer cells

    Patricia S. Steeg

  • Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

    Paul R. Lockman;Rajendar K. Mittapalli;Kunal S. Taskar;Vinay Rudraraju

  • Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development.

    A. M. Rosengard;H. C. Krutzsch;A. Shearn;J. R. Biggs

  • Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity.

    P S Steeg;R N Moore;H M Johnson;J J Oppenheim

  • Antibody–drug conjugates for cancer

    Cindy H Chau;Patricia S Steeg;William D Figg

  • Breast cancer metastasis to the central nervous system.

    Robert J. Weil;Diane C. Palmieri;Julie L. Bronder;Andreas M. Stark

  • Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential.

    Generoso Bevilacqua;Mark E. Sobel;Lance A. Liotta;Patricia S. Steeg

  • Identification of a second human nm23 gene, nm23-H2.

    J. A. Stahl;A. Leone;A. M. Rosengard;L. Porter

  • Transfection of Thrombospondin 1 Complementary DNA into a Human Breast Carcinoma Cell Line Reduces Primary Tumor Growth, Metastatic Potential, and Angiogenesis

    Debra L. Weinstat-Saslow;Vivian S. Zabrenetzky;Kenneth VanHoutte;William A. Frazier

  • A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase.

    Joseph Biggs;Evelyn Hersperger;Patricia S. Steeg;Lance A. Liotta

  • Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

    Debra Weinstat-Saslow;Maria J. Merino;Richard E. Manrow;Julia A. Lawrence

  • Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain.

    Diane Palmieri;Julie L. Bronder;Jeanne M. Herring;Toshiyuki Yoneda

  • Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line : effects on tumor metastatic potential, colonization and enzymatic activity

    A Leone;U Flatow;K VanHoutte;P S Steeg

  • Metastasis: a therapeutic target for cancer

    Patricia S Steeg;Dan Theodorescu

Frequent Co-Authors

Seth M. Steinberg
Seth M. Steinberg National Institutes of Health
Lance A. Liotta
Lance A. Liotta George Mason University
George W. Sledge
George W. Sledge Stanford University
Jacek Jassem
Jacek Jassem Gdańsk Medical University
Maria J. Merino
Maria J. Merino National Institutes of Health
Dihua Yu
Dihua Yu The University of Texas MD Anderson Cancer Center
Paul S. Meltzer
Paul S. Meltzer National Institutes of Health
Suyun Huang
Suyun Huang Virginia Commonwealth University
Ann F. Chambers
Ann F. Chambers University of Western Ontario
Timothy D. Veenstra
Timothy D. Veenstra Lake Erie College of Osteopathic Medicine

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