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Biology and Biochemistry

D-Index
55
Citations
13800
World Ranking
14870
National Ranking
6224

Overview

Mark J. Pettenati is affiliated with Wake Forest University in the United States and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology. Their work spans multiple subfields including hematology, genetics, reproductive medicine, molecular biology, and public health, environmental and occupational health.

The research topics covered by Pettenati include:

  • Sperm and Testicular Function
  • Chronic Myeloid Leukemia Treatments
  • Acute Myeloid Leukemia Research
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Reproductive Biology and Fertility
  • Sexual Differentiation and Disorders
  • Renal and related cancers

Some recent publications authored or coauthored by Pettenati are:

  • In Vitro Generation of Haploid Germ Cells from Human XY and XXY Immature Testes in a 3D Organoid System, 2024, Bioengineering
  • In vitro propagation of XXY human Klinefelter spermatogonial stem cells: A step towards new fertility opportunities, 2022, Frontiers in Endocrinology
  • In Vitro Propagation of XXY Undifferentiated Mouse Spermatogonia: Model for Fertility Preservation in Klinefelter Syndrome Patients, 2021, International Journal of Molecular Sciences
  • PML-RARA Fusion Transcripts Detectable 8 Months prior to Promyelocytic Blast Crisis in Chronic Myeloid Leukemia, 2020, Case Reports in Hematology
  • Non-Nodal CD5-Negative Mantle Cell Lymphoma with Secondary TP53 Deletion, 2020, Case Reports in Hematology

Pettenati frequently publishes in venues including:

  • Case Reports in Hematology
  • Frontiers in Endocrinology
  • Bioengineering
  • International Journal of Molecular Sciences
  • American Journal of Forensic Medicine & Pathology

Collaborations with other researchers are common in Pettenati's work. Frequent coauthors include:

  • Anthony Atala
  • Hooman Sadri-Ardekani
  • Guillermo Galdon
  • Nicholas A. Deebel
  • Nima Pourhabibi Zarandi

The research focus reflects a strong involvement in the understanding and treatment of hematological malignancies such as chronic and acute myeloid leukemia, alongside investigations into fertility preservation and reproductive biology related to chromosomal abnormalities like Klinefelter syndrome.

Best Publications

  • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

    John C. Byrd;Krzysztof Mrózek;Richard K. Dodge;Andrew J. Carroll

  • Frequency of Prolonged Remission Duration after High-Dose Cytarabine Intensification in Acute Myeloid Leukemia Varies by Cytogenetic Subtype

    Clara D. Bloomfield;David Lawrence;John C. Byrd;Andrew Carroll

  • Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia

    Krzysztof Mrózek;Guido Marcucci;Deedra Nicolet;Kati S. Maharry

  • Prognostic Factors and Outcome of Core Binding Factor Acute Myeloid Leukemia Patients With t(8;21) Differ From Those of Patients With inv(16): A Cancer and Leukemia Group B Study

    Guido Marcucci;Krzysztof Mrózek;Amy S. Ruppert;Kati Maharry

  • The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

    Jan O. Korbel;Tal Tirosh-Wagner;Alexander Eckehart Urban;Xiao Ning Chen

  • Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells.

    N Quintrell;R Lebo;H Varmus;J M Bishop

  • Prospective Karyotype Analysis in Adult Acute Lymphoblastic Leukemia: The Cancer and Leukemia Group B Experience

    Meir Wetzler;Richard K. Dodge;Krzysztof Mrózek;Andrew J. Carroll

  • The human cornea has a high incidence of acquired chromosome abnormalities

    Mark J. Pettenati;Andrew J. Sweatt;Patrick Lantz;Constance A. Stanton

  • Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.

    Sherif S. Farag;Kellie J. Archer;Krzysztof Mrózek;Amy S. Ruppert

  • Repetitive Cycles of High-Dose Cytarabine Benefit Patients With Acute Myeloid Leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): Results from CALGB 8461

    John C. Byrd;Amy S. Ruppert;Krzysztof Mrózek;Andrew J. Carroll

  • Identification of a Mutation in DLX3 Associated with Tricho-Dento-Osseous (TDO) Syndrome

    Jennifer A. Price;Donald W. Bowden;J. Tim Wright;Mark J. Pettenati

  • Down syndrome congenital heart disease: a narrowed region and a candidate gene.

    Gillian M. Barlow;Xiao Ning Chen;Zheng Y. Shi;Gary E. Lyons

  • Transferable anticancer innate immunity in spontaneous regression/complete resistance mice

    Amy M. Hicks;Gregory Riedlinger;Mark C. Willingham;Martha A. Alexander-Miller

  • Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders

    M J Pettenati;M M Le Beau;R S Lemons;E A Shima

  • Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily.

    Françoise Haeseleer;Izabela Sokal;Ning Li;Ning Li;Mark Pettenati

  • Prenatal diagnosis using interphase fluorescence in situ hybridization (FISH): 2-year multi-center retrospective study and review of the literature.

    J. Tepperberg;M. J. Pettenati;P. N. Rao;C. M. Lese

  • Outcome of Induction and Postremission Therapy in Younger Adults With Acute Myeloid Leukemia With Normal Karyotype: A Cancer and Leukemia Group B Study

    Sherif S. Farag;Amy S. Ruppert;Krzysztof Mrózek;Robert J. Mayer

  • The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein.

    R. A. Pierce;E. D. Field;T. Mutis;T. N. Golovina

  • The human NACP/alpha-synuclein gene: chromosome assignment to 4q21.3-q22 and TaqI RFLP analysis.

    Xiaohua Chen;H.A.Rohan de Silva;Mark J. Pettenati;P.Nagesh Rao

  • Genetic Linkage of Hereditary Gingival Fibromatosis to Chromosome 2p21

    Thomas C. Hart;Debora Pallos;Donald W. Bowden;Joey Bolyard

Frequent Co-Authors

Andrew J. Carroll
Andrew J. Carroll University of Alabama at Birmingham
Clara D. Bloomfield
Clara D. Bloomfield The Ohio State University
Krzysztof Mrózek
Krzysztof Mrózek The Ohio State University
Richard A. Larson
Richard A. Larson University of Chicago
Bayard L. Powell
Bayard L. Powell Wake Forest University
Guido Marcucci
Guido Marcucci City Of Hope National Medical Center
Nyla A. Heerema
Nyla A. Heerema The Ohio State University
Robert J. Mayer
Robert J. Mayer Dana-Farber Cancer Institute
Vandana Shashi
Vandana Shashi Duke University
Donald W. Bowden
Donald W. Bowden Wake Forest University

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