World's Best Scientists 2026 revealed!

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Medicine

D-Index
104
Citations
49342
World Ranking
6954
National Ranking
3662

Overview

Herbert J. Zeh is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily spans the field of Medicine, with an emphasis on Oncology and Surgery. In addition, their work addresses Pulmonary and Respiratory Medicine, Epidemiology, and Cancer Research as significant subfields.

The scientist's research topics cover a range of specialized areas, including:

  • Pancreatic and Hepatic Oncology Research
  • Gallbladder and Bile Duct Disorders
  • Surgical Simulation and Training
  • Pancreatitis Pathology and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cancer Genomics and Diagnostics
  • Gastric Cancer Management and Outcomes

Herbert J. Zeh has contributed to numerous publications, appearing frequently in prominent venues. The five most frequent publication venues include:

  • Annals of Surgical Oncology (34 publications)
  • HPB (33 publications)
  • Gastrointestinal Endoscopy (15 publications)
  • Surgical Endoscopy (13 publications)
  • Annals of Surgery (12 publications)

Frequent co-authors in their research collaborations include:

  • Patricio M. Polanco (115 joint publications)
  • Melissa E. Hogg (63 joint publications)
  • Adam C. Yopp (60 joint publications)
  • Matthew R. Porembka (51 joint publications)
  • Amer H. Zureikat (50 joint publications)

Among their recent academic contributions are several papers focusing on mechanisms of cancer and cell death, with a particular focus on pancreatic cancer. Selected recent papers include:

  • "Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein," 2020, published in Autophagy
  • "Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway," 2020, published in Nature Communications
  • "Cell death in pancreatic cancer: from pathogenesis to therapy," 2021, published in Nature Reviews Gastroenterology & Hepatology
  • "The multifunctional protein HMGB1: 50 years of discovery," 2023, published in Nature Reviews Immunology
  • "PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis," 2021, published in Cell Reports

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • The Beclin 1 network regulates autophagy and apoptosis

    R Kang;H J Zeh;M T Lotze;D Tang

  • Autophagy promotes ferroptosis by degradation of ferritin

    Wen Hou;Yangchun Xie;Xinxin Song;Xiaofang Sun

  • PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity

    Daolin Tang;Rui Kang;Carolyn B. Coyne;Herbert J. Zeh

  • Endogenous HMGB1 regulates autophagy

    Daolin Tang;Rui Kang;Kristen M. Livesey;Chun-Wei Cheh

  • HMGB1 in Health and Disease

    Rui Kang;Ruochan Chen;Qiuhong Zhang;Wen Hou

  • The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity.

    Michael T. Lotze;Herbert J. Zeh;Anna Rubartelli;Louis J. Sparvero

  • Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma.

    Hideho Okada;Pawel Kalinski;Ryo Ueda;Aki Hoji

  • The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

    Yangchun Xie;Yangchun Xie;Yangchun Xie;Shan Zhu;Xinxin Song;Xiaofang Sun

  • AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity.

    Xinxin Song;Xinxin Song;Shan Zhu;Pan Chen;Wen Hou

  • Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer

    Dung T. Le;Andrea Wang-Gillam;Vincent Picozzi;Tim F. Greten

  • High-mobility group box 1, oxidative stress, and disease

    Daolin Tang;Rui Kang;Herbert J. Zeh;Michael T. Lotze

  • HMGB1 in cancer: good, bad, or both?

    Rui Kang;Qiuhong Zhang;Herbert J. Zeh;Michael T. Lotze

  • Arginine and immunity.

    Petar J. Popovic;Herbert J. Zeh;Juan B. Ochoa

  • HMGB1 release and redox regulates autophagy and apoptosis in cancer cells.

    Daolin Tang;Rui Kang;Chun-Wei Cheh;Kristen M. Livesey

  • HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells.

    Shan Zhu;Qiuhong Zhang;Xiaofang Sun;Herbert J Zeh

  • The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

    Yan Yu;Yangchun Xie;Lizhi Cao;Liangchun Yang

  • A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

    Simeon Springer;Yuxuan Wang;Marco Dal Molin;David L. Masica

  • 250 Robotic Pancreatic Resections: Safety and Feasibility

    Amer H. Zureikat;A. James Moser;Brian A. Boone;David L. Bartlett

  • Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.

    Hideaki Tahara;Herbert J. Zeh;Walter J. Storkus;Itzhak Pappo

Frequent Co-Authors

David L. Bartlett
David L. Bartlett University of Pittsburgh
Michael T. Lotze
Michael T. Lotze University of Pittsburgh
Rui Kang
Rui Kang University of Pittsburgh
Daolin Tang
Daolin Tang The University of Texas Southwestern Medical Center
Randall E. Brand
Randall E. Brand University of Pittsburgh
Timothy R. Billiar
Timothy R. Billiar University of Pittsburgh
David C. Whitcomb
David C. Whitcomb University of Pittsburgh
Guido Kroemer
Guido Kroemer Université Paris Cité
Pawel Kalinski
Pawel Kalinski Roswell Park Comprehensive Cancer Center
Haichao Wang
Haichao Wang Feinstein Institute for Medical Research

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