H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 115 Citations 45,442 299 World Ranking 148 National Ranking 4
Medicine D-index 116 Citations 45,876 304 World Ranking 1806 National Ranking 34

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • T cell

His primary areas of study are Receptor, Immunology, Cell biology, Interleukin 21 and Lymphokine-activated killer cell. The Receptor study combines topics in areas such as Molecular biology, NKG2 and Cytotoxicity. His Immunology research includes elements of Natural killer cell, Cancer research and NKG2D.

His Cell biology study deals with Natural Cytotoxicity Triggering Receptor 1 intersecting with Natural Cytotoxicity Triggering Receptor 3 and Cytolysis. In Interleukin 21, Alessandro Moretta works on issues like Interleukin 12, which are connected to Natural killer T cell, Antigen-presenting cell, Lysis and Tumor cells. He has included themes like NK-92, Perforin, Innate immune system and Lymph node in his Lymphokine-activated killer cell study.

His most cited work include:

  • Innate or Adaptive Immunity? The Example of Natural Killer Cells (1717 citations)
  • Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis (1532 citations)
  • RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS (768 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Immunology, Receptor, Molecular biology, Interleukin 21 and Cell biology. His research integrates issues of Natural killer cell and Cytotoxic T cell in his study of Immunology. The Receptor study combines topics in areas such as Cell, Human leukocyte antigen, Natural Cytotoxicity Triggering Receptor 1 and Cytolysis, Cytotoxicity.

His research integrates issues of T cell, T-cell receptor, Antigen and Antibody, Monoclonal antibody in his study of Molecular biology. His Interleukin 21 course of study focuses on Interleukin 12 and Natural killer T cell and Innate lymphoid cell. The study incorporates disciplines such as NKG2D and Immune receptor in addition to Cell biology.

He most often published in these fields:

  • Immunology (48.59%)
  • Receptor (36.69%)
  • Molecular biology (34.07%)

What were the highlights of his more recent work (between 2010-2021)?

  • Immunology (48.59%)
  • Interleukin 21 (31.85%)
  • Interleukin 12 (26.01%)

In recent papers he was focusing on the following fields of study:

His main research concerns Immunology, Interleukin 21, Interleukin 12, Immune system and Receptor. Alessandro Moretta has included themes like Cell, Hematopoietic stem cell transplantation and Cancer research in his Immunology study. His Interleukin 21 research is multidisciplinary, incorporating elements of Antigen-presenting cell and Cell biology.

Alessandro Moretta interconnects Natural killer T cell, CXCL14, Trogocytosis and CXCR3 in the investigation of issues within Interleukin 12. His studies deal with areas such as Downregulation and upregulation, Function, Signal transduction, Cytotoxicity and Effector as well as Receptor. His study in Lymphokine-activated killer cell is interdisciplinary in nature, drawing from both Natural killer cell, Tumor progression and Natural killer cell cytokine production.

Between 2010 and 2021, his most popular works were:

  • Innate or Adaptive Immunity? The Example of Natural Killer Cells (1717 citations)
  • Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity (356 citations)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (301 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • T cell

Immunology, Interleukin 21, Interleukin 12, Lymphokine-activated killer cell and NK-92 are his primary areas of study. His Immunology research includes themes of Receptor, Cancer research, Natural killer cell and Hematopoietic stem cell transplantation. His work carried out in the field of Receptor brings together such families of science as Acquired immune system, GiST and Cell biology.

His Interleukin 21 research integrates issues from Tumor microenvironment, NKG2D, Cell and Immunotherapy. The concepts of his Interleukin 12 study are interwoven with issues in CXCL10, Human leukocyte antigen and CCL21. His Lymphokine-activated killer cell research is multidisciplinary, incorporating perspectives in Natural killer T cell and Natural killer cell cytokine production.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Innate or Adaptive Immunity? The Example of Natural Killer Cells

Eric Vivier;David H. Raulet;Alessandro Moretta;Michael A. Caligiuri.
Science (2011)

2172 Citations

Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (2001)

1937 Citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (1996)

935 Citations

Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells

Daniela Pende;Silvia Parolini;Anna Pessino;Simona Sivori.
Journal of Experimental Medicine (1999)

870 Citations

NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

Massimo Vitale;Cristina Bottino;Simona Sivori;Lorenza Sanseverino.
Journal of Experimental Medicine (1998)

827 Citations

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

Cristina Bottino;Roberta Castriconi;Daniela Pende;Paola Rivera.
Journal of Experimental Medicine (2003)

808 Citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

Alessandro Moretta;Massimo Vitale;Cristina Bottino;Anna Maria Orengo.
Journal of Experimental Medicine (1993)

772 Citations

Natural killer cells and dendritic cells: rendezvous in abused tissues

Alessandro Moretta.
Nature Reviews Immunology (2002)

757 Citations

Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor.

Hideyuki Ikeda;Bernard Lethé;Frédéric Lehmann;Nicolas Van Baren.
Immunity (1997)

738 Citations

Unravelling natural killer cell function: triggering and inhibitory human NK receptors.

Lorenzo Moretta;Lorenzo Moretta;Alessandro Moretta.
The EMBO Journal (2004)

709 Citations

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