D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 57 Citations 11,304 131 World Ranking 1953 National Ranking 19

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • T cell

Miguel López-Botet focuses on Molecular biology, Receptor, CD94/NKG2, NKG2 and Immunology. His Molecular biology research incorporates elements of T cell and CD8, Antigen. Miguel López-Botet interconnects Natural killer cell, NK Cell Lectin-Like Receptor Subfamily C, Human leukocyte antigen and Signal transduction, Cell biology in the investigation of issues within Receptor.

His NK Cell Lectin-Like Receptor Subfamily C research includes themes of Human cytomegalovirus and Virology. His research in CD94/NKG2 focuses on subjects like NK Cell Lectin-Like Receptor Subfamily D, which are connected to Monoclonal antibody and KLRB1. In his work, HLA-G is strongly intertwined with HLA-E, which is a subfield of NKG2.

His most cited work include:

  • A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells (825 citations)
  • HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. (790 citations)
  • IMPLICATIONS FOR IMMUNOSURVEILLANCE OF ALTERED HLA CLASS I PHENOTYPES IN HUMAN TUMOURS (674 citations)

What are the main themes of his work throughout his whole career to date?

Miguel López-Botet mostly deals with Immunology, Molecular biology, Receptor, Cell biology and T cell. The various areas that Miguel López-Botet examines in his Immunology study include Natural killer cell and Cytotoxic T cell. His Natural killer cell research is multidisciplinary, relying on both Interleukin 21 and Cytokine.

Miguel López-Botet has researched Molecular biology in several fields, including Cell culture, Antigen, CD94/NKG2, Interleukin 2 and Monoclonal antibody. His work in CD94/NKG2 addresses issues such as NK Cell Lectin-Like Receptor Subfamily D, which are connected to fields such as NK Cell Lectin-Like Receptor Subfamily C, Receptor complex and C-type lectin. Miguel López-Botet combines subjects such as HLA-E, Human leukocyte antigen, LILRB1 and MHC class I, NKG2 with his study of Receptor.

He most often published in these fields:

  • Immunology (49.24%)
  • Molecular biology (35.03%)
  • Receptor (31.98%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (49.24%)
  • Human cytomegalovirus (16.24%)
  • Receptor (31.98%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Immunology, Human cytomegalovirus, Receptor, Immunophenotyping and Human leukocyte antigen. His research links Cell with Immunology. The Human cytomegalovirus study combines topics in areas such as Natural killer cell, HLA-E, Serology and Degranulation.

The study incorporates disciplines such as Molecular biology, CD86 and MHC class II in addition to Natural killer cell. The concepts of his Receptor study are interwoven with issues in Phenotype, LILRB1 and Cell biology. His Human leukocyte antigen research incorporates themes from Gene, Immune system, Interferon type I and Antibody, Avidity.

Between 2012 and 2021, his most popular works were:

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
  • New advances in CMV and immunosenescence. (103 citations)
  • Adaptive reconfiguration of the human NK‐cell compartment in response to cytomegalovirus: A different perspective of the host‐pathogen interaction (97 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

Immunology, Receptor, Human leukocyte antigen, Antibody-dependent cell-mediated cytotoxicity and Acquired immune system are his primary areas of study. His Immunology study frequently draws connections between related disciplines such as Interleukin 12. His Receptor study integrates concerns from other disciplines, such as LILRB1, Cell growth and Genotype.

His studies in Human leukocyte antigen integrate themes in fields like Gene expression profiling, Biomarker, Internal medicine, Breast cancer and Antibody. His study on Antibody-dependent cell-mediated cytotoxicity also encompasses disciplines like

  • Lymphocyte, Monoclonal antibody and NKG2D most often made with reference to Immunotherapy,
  • Cytotoxic T cell which is related to area like Cell biology. He studied Acquired immune system and NK Cell Lectin-Like Receptor Subfamily C that intersect with Tumor necrosis factor alpha, Cytokine, Receptor expression, Viremia and Retrospective cohort study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A.

Ni Lee;Manuel Llano;Marta Carretero;Akiko Ishitani.
Proceedings of the National Academy of Sciences of the United States of America (1998)

988 Citations

A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

Marco Colonna;Francisco Navarro;Teresa Bellón;Manuel Llano.
Journal of Experimental Medicine (1997)

969 Citations

IMPLICATIONS FOR IMMUNOSURVEILLANCE OF ALTERED HLA CLASS I PHENOTYPES IN HUMAN TUMOURS

Federico Garrido;Francisco Ruiz-Cabello;Teresa Cabrera;Juan J. Pérez-Villar.
Immunology Today (1997)

959 Citations

Imprint of human cytomegalovirus infection on the NK cell receptor repertoire.

Mónica Gumá;Ana Angulo;Carlos Vilches;Natalia Gómez-Lozano.
Blood (2004)

710 Citations

The ILT2(LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells

Francisco Navarro;Manuel Llano;Teresa Bellón;Marco Colonna.
European Journal of Immunology (1999)

402 Citations

Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts

Mónica Gumá;Matthias Budt;Andrea Sáez;Tamara Brckalo.
Blood (2006)

401 Citations

Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E.

Mar Valés‐Gómez;Hugh T. Reyburn;Robert A. Erskine;Miguel López‐Botet.
The EMBO Journal (1999)

383 Citations

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer

Manuel Llano;Ni Lee;Francisco Navarro;Pilar García.
European Journal of Immunology (1998)

378 Citations

Triggering of T cell proliferation through AIM, an activation inducer molecule expressed on activated human lymphocytes.

M Cebrián;E Yagüe;M Rincón;M López-Botet.
Journal of Experimental Medicine (1988)

343 Citations

The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules

Marta Carretero;Claudia Cantoni;Teresa Bellón;Cristina Bottino.
European Journal of Immunology (1997)

323 Citations

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