H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 19,572 96 World Ranking 8549 National Ranking 212

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Gene
  • Antibody

Massimo Vitale mainly investigates Receptor, Cell biology, Natural killer cell, NK Cell Lectin-Like Receptor Subfamily D and Lymphokine-activated killer cell. His Receptor research includes elements of Extracellular, Immunology, Transfection, Molecular biology and Human leukocyte antigen. The various areas that he examines in his Cell biology study include NKG2D, Interleukin 12 and Natural Cytotoxicity Triggering Receptor 1.

His research in Natural killer cell intersects with topics in Major histocompatibility complex and Cytolysis. His NK Cell Lectin-Like Receptor Subfamily D study combines topics in areas such as KIR2DL1 and CD94/NKG2. Interleukin 21 covers Massimo Vitale research in Lymphokine-activated killer cell.

His most cited work include:

  • Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis (1532 citations)
  • RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS (768 citations)
  • Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule (661 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Receptor, Cell biology, Immunology, Lymphokine-activated killer cell and Molecular biology. The study incorporates disciplines such as Cell, Extracellular, Natural killer cell, NK Cell Lectin-Like Receptor Subfamily D and Human leukocyte antigen in addition to Receptor. His studies deal with areas such as Natural killer T cell, Immune system and NKG2D, Cytotoxicity, Natural Cytotoxicity Triggering Receptor 3 as well as Cell biology.

In the field of Immunology, his study on Innate lymphoid cell, Innate immune system, Dendritic cell and Interferon gamma overlaps with subjects such as Population. His Lymphokine-activated killer cell research entails a greater understanding of Interleukin 21. His Molecular biology study incorporates themes from T cell, Monoclonal antibody, Antibody, Immunoglobulin superfamily and Signal transduction.

He most often published in these fields:

  • Receptor (48.60%)
  • Cell biology (40.19%)
  • Immunology (35.51%)

What were the highlights of his more recent work (between 2012-2020)?

  • Cell biology (40.19%)
  • Receptor (48.60%)
  • Immunology (35.51%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Receptor, Immunology, Immune system and Cell. His Cell biology study combines topics from a wide range of disciplines, such as Chemokine, Cell cycle, Interleukin 12 and Cell type. Interleukin 12 and Interleukin 21 are frequently intertwined in his study.

His Receptor research includes themes of Extracellular, NKG2D, Cytotoxicity, Human leukocyte antigen and Extracellular matrix. His study in Immune system focuses on Lymphokine-activated killer cell in particular. Massimo Vitale has researched Cell in several fields, including Cancer research, Interferon gamma, Evasion and Varicella zoster virus.

Between 2012 and 2020, his most popular works were:

  • Effect of tumor cells and tumor microenvironment on NK-cell function (196 citations)
  • Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC (118 citations)
  • Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation. (68 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Gene
  • Antibody

Massimo Vitale spends much of his time researching Receptor, Immunology, Immune system, Cell biology and Cancer research. Many of his research projects under Receptor are closely connected to Viral entry with Viral entry, tying the diverse disciplines of science together. His work on Varicella zoster virus, Evasion, Interferon gamma and HLA-E as part of general Immunology study is frequently connected to Cytomegalovirus, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

The concepts of his Cell biology study are interwoven with issues in Antibody-dependent cell-mediated cytotoxicity, NKG2D, Innate immune system, Effector functions and Cell type. His study in Cancer research is interdisciplinary in nature, drawing from both Hematopoietic stem cell transplantation, Leukemia, Human leukocyte antigen and Monoclonal antibody. His Lymphokine-activated killer cell research is multidisciplinary, relying on both Tumor progression and Tumor Escape.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (2001)

1937 Citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

Alessandro Moretta;Cristina Bottino;Massimo Vitale;Daniela Pende.
Annual Review of Immunology (1996)

935 Citations

NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

Massimo Vitale;Cristina Bottino;Simona Sivori;Lorenza Sanseverino.
Journal of Experimental Medicine (1998)

827 Citations

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

Cristina Bottino;Roberta Castriconi;Daniela Pende;Paola Rivera.
Journal of Experimental Medicine (2003)

808 Citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

Alessandro Moretta;Massimo Vitale;Cristina Bottino;Anna Maria Orengo.
Journal of Experimental Medicine (1993)

772 Citations

Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor.

Hideyuki Ikeda;Bernard Lethé;Frédéric Lehmann;Nicolas Van Baren.
Immunity (1997)

738 Citations

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

Nicolai Wagtmann;Roberto Biassoni;Claudia Cantoni;Simonetta Verdiani.
Immunity (1995)

680 Citations

Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells

Roberta Castriconi;Claudia Cantoni;Mariella Della Chiesa;Massimo Vitale.
Proceedings of the National Academy of Sciences of the United States of America (2003)

588 Citations

p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation

Simona Sivori;Massimo Vitale;Luigia Morelli;Lorenza Sanseverino.
Journal of Experimental Medicine (1997)

580 Citations

CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: Induction of cytokine release and cytotoxicity against tumors and dendritic cells

Simona Sivori;Michela Falco;Mariella Della Chiesa;Simona Carlomagno.
Proceedings of the National Academy of Sciences of the United States of America (2004)

521 Citations

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