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Immunology

D-Index
68
Citations
22649
World Ranking
2553
National Ranking
25

Overview

William W. Agace is affiliated with Lund University in Sweden and has a research focus concentrated in the fields of Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields, including Immunology, Molecular Biology, Epidemiology, Oncology, and Genetics.

The scientist's research explores key topics such as Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, IL-33, ST2, and ILC Pathways, Gut microbiota and health, Helicobacter pylori-related gastroenterology studies, and Single-cell and spatial transcriptomics.

William W. Agace has contributed to multiple publications in noteworthy scientific venues. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), where they published four papers, as well as Immunity with three publications. Other venues with multiple contributions are Mucosal Immunology and Science Immunology with two publications each, and Nature Communications with two publications.

Collaboration is a significant part of their research activity. Frequent coauthors include Urs Mörbe, Thomas M. Fenton, Knut Kotarsky, Allan McI. Mowat, and Peter Leth Jørgensen.

Recent papers showcasing William W. Agace's research output include:

  • Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut, 2021, Nature Microbiology
  • Human gut-associated lymphoid tissues (GALT); diversity, structure, and function, 2021, Mucosal Immunology
  • Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity, 2020, Immunity
  • A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut, 2022, Immunity
  • Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3 + CD8 + T regs, 2021, Science Immunology

Best Publications

  • Regional specialization within the intestinal immune system

    Allan M. Mowat;William Winston Agace

  • Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6C hi monocyte precursors

    C. C. Bain;C. L. Scott;Heli Uronen-Hansson;Sigurdur Gudjonsson

  • Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract

    I Connell;W Agace;P Klemm;M Schembri

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Functional specialization of gut CD103^+ dendritic cells in the regulation of tissue-selective T cell homing

    Bengt Johansson-Lindbom;Marcus Svensson;Oliver Pabst;Caroline Palmqvist

  • Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions

    Olga Schulz;Elin Jaensson;Emma K. Persson;Xiaosun Liu

  • Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans.

    Elin Jaensson;Heli Uronen-Hansson;Oliver Pabst;Bertus Eksteen

  • Human G Protein–Coupled Receptor Gpr-9-6/Cc Chemokine Receptor 9 Is Selectively Expressed on Intestinal Homing T Lymphocytes, Mucosal Lymphocytes, and Thymocytes and Is Required for Thymus-Expressed Chemokine–Mediated Chemotaxis

    Brian A. Zabel;William W. Agace;James J. Campbell;Heidi M. Heath

  • IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.

    Emma K. Persson;Heli Uronen-Hansson;Monika Maria Semmrich;Aymeric Marie Christian Rivollier

  • Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity.

    Eric J. Kunkel;James J. Campbell;Guttorm Haraldsen;Junliang Pan

  • Essential role for CD103 in the T cell–mediated regulation of experimental colitis

    Oliver Annacker;Janine L. Coombes;Vivianne Malmstrom;Holm H. Uhlig

  • Selective Generation of Gut Tropic T Cells in Gut-associated Lymphoid Tissue (GALT): Requirement for GALT Dendritic Cells and Adjuvant

    Bengt Johansson-Lindbom;Marcus Svensson;Marc-André Wurbel;Bernard Malissen

  • Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice

    Michael P. Schön;Anu Arya;Elizabeth A. Murphy;Cassandra M. Adams

  • CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa.

    Marcus Svensson;Jan Marsal;Anna Ericsson;Laura Carramolino

  • Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.

    Serge A van de Pavert;Brenda J Olivier;Gera Goverse;Mark F Vondenhoff

  • Human gut-associated lymphoid tissues (GALT); diversity, structure, and function.

    Urs M Mörbe;Peter B Jørgensen;Thomas M Fenton;Nicole von Burg

  • IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively

    Dorine Sichien;Charlotte L Scott;Liesbet Martens;Matthias Vanderkerken

  • Interleukin-8 and the neutrophil response to mucosal gram-negative infection.

    W W Agace;S R Hedges;M Ceska;C Svanborg

  • Selective cytokine production by epithelial cells following exposure to Escherichia coli.

    W Agace;S Hedges;U Andersson;J Andersson

  • DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

    Lionel F. Poulin;Yasmin Reyal;Heli Uronen-Hansson;Barbara U. Schraml

  • Generation of gut-homing T cells and their localization to the small intestinal mucosa

    Bengt Johansson-Lindbom;William W. Agace

  • Mucosal T Lymphocyte Numbers Are Selectively Reduced in Integrin αE (CD103)-Deficient Mice

    Unknown

Frequent Co-Authors

Catharina Svanborg
Catharina Svanborg Lund University
Graham Anderson
Graham Anderson University of Birmingham
Allan McI. Mowat
Allan McI. Mowat University of Glasgow
Bernard Malissen
Bernard Malissen Aix-Marseille University
Søren Brunak
Søren Brunak University of Copenhagen
Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Mikael Sigvardsson
Mikael Sigvardsson Lund University
Sten Eirik W. Jacobsen
Sten Eirik W. Jacobsen University of Oxford
Jenny Mjösberg
Jenny Mjösberg Karolinska Institute
Bernhard Holzmann
Bernhard Holzmann Technical University of Munich

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