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Biology and Biochemistry
Poland
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
17773
World Ranking
5659
National Ranking
5

Tad A. Holak publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Tad A. Holak sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 241 publications — 64th percentile

64% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Tad A. Holak D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Tad A. Holak sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 74 D-Index — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Poland Leader Award
  • 2025 - Research.com Biology and Biochemistry in Poland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Poland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Poland Leader Award

Overview

Tad A. Holak is affiliated with Jagiellonian University in Poland. Their research spans various topics within medicine and biochemistry, genetics, and molecular biology, with a particular focus on oncology and molecular biology.

Their work involves significant contributions to cancer immunotherapy and biomarkers, CAR-T cell therapy research, and peptidase inhibition and analysis. Other notable research topics include monoclonal and polyclonal antibodies research, ubiquitin and proteasome pathways, click chemistry and its applications, and chemical synthesis and analysis.

Frequent co-authors collaborating with Holak include:

  • Katarzyna Magiera-Mularz
  • Bogdan Musielak
  • Łukasz Skalniak
  • Jacek Plewka
  • Ewa Surmiak

Their publications have appeared most frequently in journals such as:

  • Molecules
  • Journal of Medicinal Chemistry
  • ACS Medicinal Chemistry Letters
  • bioRxiv (Cold Spring Harbor Laboratory)
  • iScience

Recent papers authored or co-authored by Tad A. Holak include:

  • Human and mouse PD-L1: similar molecular structure, but different druggability profiles, 2020, iScience
  • Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction, 2021, Journal of Medicinal Chemistry
  • Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint, 2020, Journal of Medicinal Chemistry
  • Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists, 2021, ACS Medicinal Chemistry Letters
  • Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions, 2020, Angewandte Chemie International Edition

Holak's research centers on immune checkpoint regulation with a strong emphasis on PD-1/PD-L1 interactions and small-molecule inhibitors. Their work integrates organic chemistry approaches with biological evaluation to explore new avenues in cancer immunotherapy.

Best Publications

  • Lifeact: a versatile marker to visualize F-actin

    Julia Riedl;Alvaro H. Crevenna;Kai Kessenbrock;Jerry Haochen Yu

  • Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.

    Krzysztof M. Zak;Radoslaw Kitel;Sara Przetocka;Przemyslaw Golik

  • Filamins: promiscuous organizers of the cytoskeleton

    Grzegorz M. Popowicz;Michael Schleicher;Angelika A. Noegel;Tad A. Holak

  • Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

    Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Guzik;Bartosz J. Zieba

  • Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2

    Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Magiera;Alexander Dömling

  • Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53.

    Raphael Stoll;Christian Renner;Silke Hansen;Stefan Palme

  • Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1

    Katarzyna Guzik;Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Magiera

  • Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells

    Lukasz Skalniak;Krzysztof M Zak;Katarzyna Guzik;Katarzyna Magiera

  • Structure in solution of the major cold-shock protein from Bacillus subtilis.

    A Schnuchel;R Wiltscheck;M Czisch;M Herrler

  • Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery

    Grzegorz M Popowicz;Anna Czarna;Siglinde Wolf;Kan Wang

  • Structure of the stapled p53 peptide bound to Mdm2.

    Sohee Baek;Peter S. Kutchukian;Gregory L. Verdine;Robert Huber

  • Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions.

    Wenzel Kalus;Markus Zweckstetter;Christian Renner;Yolanda Sanchez

  • Expansion of the genetic code enables design of a novel "gold'' class of green fluorescent proteins

    Jae Hyun Bae;Marina Rubini;Gregor Jung;Georg Wiegand

  • Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.

    Grzegorz M. Popowicz;Anna Czarna;Tad A. Holak

  • Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases.

    Thomas Weber;Roland Baumgartner;Christian Renner;Mohamed A Marahiel

  • Mutational analysis of the putative nucleic acid-binding surface of the cold-shock domain, CspB, revealed an essential role of aromatic and basic residues in binding of single-stranded DNA containing the Y-box motif.

    Katja Schröder;Peter Graumann;Arndt Schnuchel;Tad A. Holak

  • RELAXATION MATRIX REFINEMENT OF THE SOLUTION STRUCTURE OF SQUASH TRYPSIN INHIBITOR

    M. Nilges;J. Habazettl;A.T. Brünger;T.A. Holak

  • The Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious

    Grzegorz M. Popowicz;Alexander Dömling;Tad A. Holak

  • Reaction Mechanism of Escherichia coli Dihydrodipicolinate Synthase Investigated by X-ray Crystallography and NMR Spectroscopy†,‡

    Stefan Blickling;Christian Renner;Bernd Laber;Hans-Dieter Pohlenz

  • Protein solubility

    Pawel Smialowski;Antonio J. Martin-Galiano;Aleksandra Mikolajka;Tobias Girschick

Frequent Co-Authors

Alexander Dömling
Alexander Dömling Palacký University, Olomouc
Robert Huber
Robert Huber University of Duisburg-Essen
Angelika A. Noegel
Angelika A. Noegel University of Cologne
Michael Schleicher
Michael Schleicher Ludwig-Maximilians-Universität München
Robert Huber
Robert Huber Agricultural & Applied Economics Association
Richard A. Engh
Richard A. Engh University of Tromsø - The Arctic University of Norway
Michael Czisch
Michael Czisch Max Planck Society
Wolfgang Voelter
Wolfgang Voelter University of Tübingen
Markus Zweckstetter
Markus Zweckstetter German Center for Neurodegenerative Diseases
Rupert Timpl
Rupert Timpl Max Planck Society

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Each of these career pathways builds on a strong foundation in biology and biochemistry, allowing graduates to apply their scientific knowledge in rewarding, in-demand healthcare fields.

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