D-Index & Metrics Best Publications

Tad A. Holak

Jagiellonian University
Poland

Biology and Biochemistry

Poland

2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Biology and Biochemistry D-index 63 Citations 12,895 175 World Ranking 6665 National Ranking 4

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Poland Leader Award

2022 - Research.com Biology and Biochemistry in Poland Leader Award

Overview

What is he best known for?

The fields of study Tad A. Holak is best known for:

Enzyme
Gene
DNA

His Organic chemistry study typically links adjacent topics like Molecule and Dimer. Molecule is frequently linked to Organic chemistry in his study. Biochemistry is closely attributed to Binding site in his study. Tad A. Holak integrates many fields, such as Gene and Peptide sequence, in his works. His Plasma protein binding research extends to Cell biology, which is thematically connected. His study in Cell biology extends to Plasma protein binding with its themes. Tad A. Holak incorporates Small molecule and Drug discovery in his research. Tad A. Holak undertakes multidisciplinary studies into Drug discovery and Small molecule in his work. While working in this field, he studies both Computational biology and Biophysics.

His most cited work include:

Lifeact: a versatile marker to visualize F-actin (1811 citations)
Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1 (333 citations)
Filamins: promiscuous organizers of the cytoskeleton (271 citations)

What are the main themes of his work throughout his whole career to date

Tad A. Holak combines Biochemistry and Immunology in his research. Tad A. Holak performs multidisciplinary study in the fields of Immunology and Biochemistry via his papers. As part of his studies on Stereochemistry, Tad A. Holak often connects relevant subjects like Nuclear magnetic resonance spectroscopy. His Nuclear magnetic resonance spectroscopy study frequently intersects with other fields, such as Stereochemistry. He incorporates Cell biology and Gene in his research. His Organic chemistry study frequently links to adjacent areas such as Molecule. His study brings together the fields of Organic chemistry and Molecule. His studies link MDMX with Mdm2. MDMX is often connected to Mdm2 in his work.

Tad A. Holak most often published in these fields:

Biochemistry (82.00%)
Gene (48.67%)
Stereochemistry (44.67%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure in solution of the major cold-shock protein from Bacillus subtilis.

A Schnuchel;R Wiltscheck;M Czisch;M Herrler.
Nature (1993)

286 Citations

Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.

Krzysztof M. Zak;Radoslaw Kitel;Sara Przetocka;Przemyslaw Golik.
Structure (2015)

267 Citations

Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions.

Wenzel Kalus;Markus Zweckstetter;Christian Renner;Yolanda Sanchez.
The EMBO Journal (1998)

262 Citations

Expansion of the genetic code enables design of a novel "gold'' class of green fluorescent proteins

Jae Hyun Bae;Marina Rubini;Gregor Jung;Georg Wiegand.
Journal of Molecular Biology (2003)

258 Citations

Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery

Grzegorz M Popowicz;Anna Czarna;Siglinde Wolf;Kan Wang.
Cell Cycle (2010)

256 Citations

Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases.

Thomas Weber;Roland Baumgartner;Christian Renner;Mohamed A Marahiel.
Structure (2000)

232 Citations

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Guzik;Bartosz J. Zieba.
Oncotarget (2016)

228 Citations

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.

Grzegorz M. Popowicz;Anna Czarna;Tad A. Holak.
Cell Cycle (2008)

214 Citations

Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2

Krzysztof M. Zak;Przemyslaw Grudnik;Katarzyna Magiera;Alexander Dömling.
Structure (2017)

211 Citations

Mutational analysis of the putative nucleic acid-binding surface of the cold-shock domain, CspB, revealed an essential role of aromatic and basic residues in binding of single-stranded DNA containing the Y-box motif.

Katja Schröder;Peter Graumann;Arndt Schnuchel;Tad A. Holak.
Molecular Microbiology (1995)

201 Citations

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