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Genetics

D-Index
60
Citations
62195
World Ranking
3088
National Ranking
1346

Overview

Manuel A. Rivas is affiliated with Stanford University in the United States and has contributed extensively to research in the fields of biochemistry, genetics, molecular biology, and medicine. Their work covers a broad spectrum of genetics and molecular biology, with a focus on subfields such as genetics, molecular biology, epidemiology, statistics and probability, and cardiology and cardiovascular medicine.

The primary topics covered in their research include genetic associations and epidemiology, statistical methods and inference, bioinformatics and genomic networks, genomics and rare diseases, gene expression and cancer classification, liver disease diagnosis and treatment, and genetic and phenotypic traits in livestock.

Manuel A. Rivas has published frequently in several venues, most notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Genetics
  • PLoS Genetics
  • Nature Communications
  • UNC Libraries

Recent papers authored or co-authored by Manuel A. Rivas include:

  • A cross-population atlas of genetic associations for 220 human phenotypes, 2021, Nature Genetics
  • Genetics of 35 blood and urine biomarkers in the UK Biobank, 2021, Nature Genetics
  • GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background, 2021, eLife
  • Significant sparse polygenic risk scores across 813 traits in UK Biobank, 2022, PLoS Genetics
  • Race, socioeconomic deprivation, and hospitalization for COVID-19 in English participants of a national biobank, 2020, International Journal for Equity in Health

Frequent collaborators in Manuel A. Rivas's research include:

  • Yosuke Tanigawa
  • Robert Tibshirani
  • Trevor Hastie
  • Johanne Marie Justesen
  • Mark J. Daly

Their work often involves integrating complex genetic data to understand human phenotypes and disease risk, utilizing statistical and computational methods in genetics and epidemiology. The focus on polygenic risk scores and cross-population genetic associations reflects an interest in both the broad genetic landscape and specific molecular mechanisms.

Best Publications

  • A framework for variation discovery and genotyping using next-generation DNA sequencing data

    Mark A DePristo;Eric Banks;Ryan Poplin;Kiran V Garimella

  • Analysis of protein-coding genetic variation in 60,706 humans

    Monkol Lek;Konrad J. Karczewski;Konrad J. Karczewski;Eric V. Minikel;Eric V. Minikel;Kaitlin E. Samocha

  • Table S2: Trans-factors and trinucleotide repeat instability Trans-factor

    Arturo López Castel;John D Cleary;Christopher E Pearson

  • The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

    Kristin G. Ardlie;David S. Deluca;Ayellet V. Segrè

  • Transcriptome and genome sequencing uncovers functional variation in humans

    Tuuli Lappalainen;Michael Sammeth;Marc R. Friedländer;Peter A. C. ‘t Hoen

  • A cross-population atlas of genetic associations for 220 human phenotypes

    Saori Sakaue;Masahiro Kanai;Yosuke Tanigawa;Juha Karjalainen

  • Correction: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

    Jialiang Yang;Tao Huang;Francesca Petralia;Quan Long

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Landscape of X chromosome inactivation across human tissues

    Taru Tukiainen;Taru Tukiainen;Alexandra-Chloé Villani;Alexandra-Chloé Villani;Angela Yen;Angela Yen;Manuel A. Rivas;Manuel A. Rivas;Manuel A. Rivas

  • Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

    Manuel A. Rivas;Manuel A. Rivas;Manuel A. Rivas;Mélissa Beaudoin;Agnes Gardet;Christine Stevens

  • Opportunities and challenges for transcriptome-wide association studies.

    Michael Wainberg;Nasa Sinnott-Armstrong;Nicholas Mancuso;Alvaro N. Barbeira

  • Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

    Ron Do;Ron Do;Nathan O. Stitziel;Hong Hee Won;Hong Hee Won;Anders Berg Jørgensen

  • Testing for an unusual distribution of rare variants.

    Benjamin Michael Neale;Manuel A. Rivas;Manuel A. Rivas;Benjamin F. Voight;Benjamin F. Voight;David Matthew Altshuler;David Matthew Altshuler

  • A map of human genome variation from population-scale sequencing

    Richard M. Durbin;David L. Altshuler;Gonçalo R. Abecasis;David R. Bentley

  • Genetics of 35 blood and urine biomarkers in the UK Biobank

    Nasa Sinnott-Armstrong;Nasa Sinnott-Armstrong;Nasa Sinnott-Armstrong;Yosuke Tanigawa;David Amar;David Amar;Nina Mars

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency

    Sarah E Calvo;Elena J Tucker;Elena J Tucker;Alison G Compton;Denise M Kirby

  • Effect of predicted protein-truncating genetic variants on the human transcriptome

    Manuel A. Rivas;Matti Pirinen;Donald F. Conrad;Monkol Lek

  • Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

    Elise Ruark;Katie Snape;Peter Humburg;Chey Loveday

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Jason Flannick;Tanya M. Teslovich;Anubha Mahajan

Frequent Co-Authors

Mark J. Daly
Mark J. Daly Massachusetts General Hospital
David Altshuler
David Altshuler Harvard University
Erik Ingelsson
Erik Ingelsson Stanford University
Benjamin M. Neale
Benjamin M. Neale Harvard University
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
Andrew P. Morris
Andrew P. Morris University of Liverpool
Paul W. Franks
Paul W. Franks Lund University
Tonu Esko
Tonu Esko University of Tartu

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