Colin R. Jefcoate

Overview

Best Publications

• Regulation of intramitochondrial cholesterol transfer to side-chain cleavage cytochrome P-450 in rat adrenal gland.

  Christopher T. Privalle;Joseph F. Crivello;Colin R. Jefcoate

  483
  Citations

• Cytochrome P450 CYP1B1 determines susceptibility to 7,12-dimethylbenz[a]anthracene-induced lymphomas

  Jeroen T. M. Buters;Shuichi Sakai;Thomas Richter;Thierry Pineau

  475
  Citations

• Tissue-specific synthesis and oxidative metabolism of estrogens.

  Colin R. Jefcoate;Joachim G. Liehr;Richard J. Santen;Thomas R. Sutter

  370
  Citations

• Mitochondrial Cytochrome P450 A COMPONENT OF CHICK KIDNEY 25-HYDROXYCHOLECALCIFEROL-1α-HYDROXYLASE

  Jacob G. Ghazarian;Colin R. Jefcoate;Joyce C. Knutson;William H. Orme-Johnson

  313
  Citations

• Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells.

  Irina P. Artemenko;Dong Zhao;Dale B. Hales;Karen H. Hales

  300
  Citations

• Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s : cloning, sequence determination and tissue expression

  U Savas;K K Bhattacharyya;M Christou;D L Alexander

  297
  Citations

• The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells : evidence for induction of a novel 17β-estradiol 4-hydroxylase

  David C. Spink;Carrie L. Hayes;Nina R. Young;Nina R. Young;Maro Christou

  285
  Citations

• Regulation of cholesterol movement to mitochondrial cytochrome P450scc in steroid hormone synthesis

  Colin R. Jefcoate;Brian C. McNamara;Irina Artemenko;Takeshi Yamazaki

  253
  Citations

• Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue- specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation

  KK Bhattacharyya;PB Brake;SE Eltom;SA Otto

  246
  Citations

• Fungal cytochrome P450 monooxygenases: Their distribution, structure, functions, family expansion, and evolutionary origin

  Wanping Chen;Mi-Kyung Lee;Colin Jefcoate;Sun Chang Kim

  244
  Citations

• Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis.

  David L. Alexander;Leonardo G. Ganem;Pedro Fernandez-Salguero;Frank Gonzalez

  229
  Citations

• High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex

  Colin Jefcoate

  226
  Citations

• Characterization of the Mouse Cyp1B1 Gene IDENTIFICATION OF AN ENHANCER REGION THAT DIRECTS ARYL HYDROCARBON RECEPTOR-MEDIATED CONSTITUTIVE AND INDUCED EXPRESSION

  Leying Zhang;Üzen Savas;David L. Alexander;Colin R. Jefcoate

  176
  Citations

• Mechanism of corticotropin action in rat adrenal cells I. The effects of inhibitors of protein synthesis and of microfilament formation on corticosterone synthesis

  Joseph F. Crivello;Colin R. Jefcoate

  173
  Citations

• Characterization of CYP1B1 and CYP1A1 Expression in Human Mammary Epithelial Cells: Role of the Aryl Hydrocarbon Receptor in Polycyclic Aromatic Hydrocarbon Metabolism

  Michele Campaigne Larsen;William G. R. Angus;Paul B. Brake;Sakina E. Eltom

  166
  Citations

• ACTH regulation of cholesterol movement in isolated adrenal cells

  Colin R. Jefcoate;Michael J. Dibartolomeis;Cristopher A. Williams;Brian C. McNamara

  152
  Citations

• Cytochromes CYP1A1 and CYP1B1 in the rat mammary gland: Cell-specific expression and regulation by polycyclic aromatic hydrocarbons and hormones

  Maro Christou;Uzen Savas;Shelly Schroeder;Xin Shen

  150
  Citations

• EFFECT OF ACTH ON ADRENAL MITOCHONDRIAL CYTOCHROME P‐450 IN THE RAT*

  Alexander C. Brownie;Josephine Alfano;Colin R. Jefcoate;William Orme-Johnson

  148
  Citations

• Polycyclic aromatic hydrocarbon metabolism in rat adrenal, ovary, and testis microsomes is catalyzed by the same novel cytochrome P450 (P450RAP)

  S Otto;K K Bhattacharyya;C R Jefcoate

  146
  Citations

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits steroidogenesis in the rat testis by inhibiting the mobilization of cholesterol to cytochrome P450scc.

  Robert W. Moore;Colin R. Jefcoate;Richard E. Peterson

  144
  Citations