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Biology and Biochemistry

D-Index
59
Citations
14086
World Ranking
12425
National Ranking
5319

Overview

David H. Sherr is affiliated with Boston University in the United States and has a research focus primarily in the fields of medicine and immunology and microbiology. Their work encompasses a variety of subfields including immunology, oncology, biological psychiatry, health, toxicology and mutagenesis, and molecular biology.

The scientist's research topics cover several key areas, such as immune cells in cancer, tryptophan and brain disorders, cancer immunotherapy and biomarkers, toxic organic pollutants impact, immunotherapy and immune responses, immune cell function and interaction, and monoclonal and polyclonal antibodies research.

David H. Sherr has published frequently in several venues. Key publication outlets include:

  • The Journal of Immunology
  • International Journal of Molecular Sciences
  • Nature Neuroscience
  • Proceedings of the National Academy of Sciences
  • Journal of Clinical Investigation

Some recent research papers illustrate the range and focus of their work. Notable publications include:

  • How the AHR Became Important in Cancer: The Role of Chronically Active AHR in Cancer Aggression, 2020, International Journal of Molecular Sciences
  • AHR is a Zika virus host factor and a candidate target for antiviral therapy, 2020, Nature Neuroscience
  • Tolerogenic nanoparticles suppress central nervous system inflammation, 2020, Proceedings of the National Academy of Sciences
  • The aryl hydrocarbon receptor suppresses immunity to oral squamous cell carcinoma through immune checkpoint regulation, 2021, Proceedings of the National Academy of Sciences
  • Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease, 2021, Journal of Clinical Investigation

The scientist collaborates with several frequent coauthors. These include Zhongyan Wang, Megan Snyder, Brian Lara, Francisco J. Quintana, and Jessica E. Kenison. The number of collaborations with these coauthors ranges from five to ten publications each, reflecting sustained research partnerships.

Best Publications

  • Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

    Shyr-Te Ju;D. J. Panka;Haili Cui;R. Ettinger

  • The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

    Lionel Apetoh;Francisco J Quintana;Caroline Pot;Nicole Joller

  • Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells.

    M Wu;H Lee;R E Bellas;S L Schauer

  • Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals.

    Tiina Matikainen;Gloria I. Perez;Andrea Jurisicova;Andrea Jurisicova;James K. Pru

  • Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

    Maisa C. Takenaka;Galina Gabriely;Veit Rothhammer;Ivan D. Mascanfroni

  • Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages.

    Smitha Krishnan;Yufang Ding;Nima Saedi;Maria Choi

  • NF-κB and epithelial to mesenchymal transition of cancer†

    Chengyin Min;Sean F. Eddy;Sean F. Eddy;David H. Sherr;David H. Sherr;Gail E. Sonenshein;Gail E. Sonenshein

  • The RelA NF-κB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c- myc promoter in mammary cells

    Dong W. Kim;Lee Gazourian;Shafat A. Quadri;Raphaëlle Romieu-Mourez

  • Green tea extracts decrease carcinogen‐induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture

    Kathryn T. Kavanagh;Laurie J. Hafer;Dong W. Kim;Koren K. Mann

  • Aryl Hydrocarbon Receptor Control of Adaptive Immunity

    Francisco J. Quintana;David H. Sherr

  • Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors.

    Nicolas Currier;Sandra E. Solomon;Elizabeth G. Demicco;Donny L.F. Chang

  • Repression of Aryl Hydrocarbon Receptor (AHR) Signaling by AHR Repressor: Role of DNA Binding and Competition for AHR Nuclear Translocator

    Brad R. Evans;Sibel I. Karchner;Lenka L. Allan;Richard S. Pollenz

  • The aryl hydrocarbon receptor, a basic helix-loop-helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse.

    Rodolfo Robles;Yutaka Morita;Koren K. Mann;Gloria I. Perez

  • Ligand Activation of the Aromatic Hydrocarbon Receptor Transcription Factor Drives Bax-Dependent Apoptosis in Developing Fetal Ovarian Germ Cells

    Tiina M. Matikainen;Toshitake Moriyama;Yutaka Morita;Gloria I. Perez

  • Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives

    Philippe Grandjean;Robert Barouki;David C. Bellinger;Ludwine Casteleyn

  • Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor.

    Mark E. Hahn;Lenka L. Allan;David H. Sherr

  • Inhibition of c-myc expression induces apoptosis of WEHI 231 murine B cells.

    M Wu;M Arsura;R E Bellas;M J FitzGerald

  • The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation.

    Brenden W. Smith;Brenden W. Smith;Sarah S. Rozelle;Sarah S. Rozelle;Amy Leung;Amy Leung;Jessalyn Ubellacker

  • Mechanisms of environmental influence on human autoimmunity: a National Institute of Environmental Health Sciences expert panel workshop.

    Carlo Selmi;Patrick S.C. Leung;David H. Sherr;Marilyn Diaz

  • A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis

    Jennifer J. Schlezinger;Donghui Liu;Marganit Farago;David C. Seldin

Frequent Co-Authors

Martin E. Dorf
Martin E. Dorf Harvard University
Francisco J. Quintana
Francisco J. Quintana Harvard Medical School
Gail E. Sonenshein
Gail E. Sonenshein Tufts University
Mark E. Hahn
Mark E. Hahn Woods Hole Oceanographic Institution
David C. Seldin
David C. Seldin Boston University
Robert Barouki
Robert Barouki Université Paris Cité
Jonathan L. Tilly
Jonathan L. Tilly Northeastern University
Ann Marshak-Rothstein
Ann Marshak-Rothstein University of Massachusetts Chan Medical School
Joachim L. Schultze
Joachim L. Schultze University of Bonn
Lee Gehrke
Lee Gehrke Harvard University

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