D-Index & Metrics Best Publications
Lee Gehrke

Lee Gehrke

Harvard University
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • RNA

His primary areas of investigation include Virology, Zika virus, Dengue virus, Cell biology and CRISPR. His Virology research is multidisciplinary, relying on both Molecular epidemiology and Disease epidemiology. His work on Zika virus is being expanded to include thematically relevant topics such as Outbreak.

He's looking at Dengue virus as part of his Dengue fever and Immunology and Dengue virus study. In the field of Cell biology, his study on Progenitor cell and Corticogenesis overlaps with subjects such as PTEN. His CRISPR research integrates issues from Infectious disease and Molecular diagnostics.

His most cited work include:

  • Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components (502 citations)
  • Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components (502 citations)
  • Field-deployable viral diagnostics using CRISPR-Cas13 (388 citations)

What are the main themes of his work throughout his whole career to date?

Lee Gehrke mainly focuses on Virology, RNA, Cell biology, Molecular biology and Zika virus. His study involves Dengue virus and Dengue fever, a branch of Virology. His study in the field of Untranslated region is also linked to topics like Alfalfa mosaic virus.

His Cell biology research incorporates elements of Translation, Innate immune system, Ribosome and Cellular differentiation. His biological study spans a wide range of topics, including Nucleic acid sequence, Non-coding RNA, Biochemistry and Base pair. His study explores the link between Zika virus and topics such as CRISPR that cross with problems in Synthetic biology.

He most often published in these fields:

  • Virology (55.40%)
  • RNA (46.04%)
  • Cell biology (25.90%)

What were the highlights of his more recent work (between 2016-2021)?

  • Virology (55.40%)
  • Zika virus (25.18%)
  • Antibody (14.39%)

In recent papers he was focusing on the following fields of study:

Virology, Zika virus, Antibody, Progenitor cell and Dengue virus are his primary areas of study. His work on Dengue fever as part of his general Virology study is frequently connected to In patient, thereby bridging the divide between different branches of science. His Zika virus research is multidisciplinary, incorporating perspectives in Cell, CRISPR, Stem cell, Host factor and Neuroscience.

His CRISPR research focuses on Arbovirus and how it connects with Genome. His Antibody research includes themes of Alphavirus, Serotype and Antigen. Lee Gehrke has included themes like Translation, Induced pluripotent stem cell and Cortex in his Progenitor cell study.

Between 2016 and 2021, his most popular works were:

  • Field-deployable viral diagnostics using CRISPR-Cas13 (388 citations)
  • Field-deployable viral diagnostics using CRISPR-Cas13 (388 citations)
  • Zika virus evolution and spread in the Americas (230 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • RNA

His main research concerns Virology, Zika virus, Dengue virus, Progenitor cell and Cell biology. Lee Gehrke studies Dengue fever which is a part of Virology. His work deals with themes such as Outbreak, Molecular epidemiology and Disease epidemiology, which intersect with Zika virus.

The study incorporates disciplines such as Neuroglia, Microglia, Induced pluripotent stem cell, Antibody and Cell type in addition to Dengue virus. His study in Progenitor cell is interdisciplinary in nature, drawing from both Lineage, Haematopoiesis, GATA1, Cellular differentiation and Ribosomal protein. His research in Cell biology intersects with topics in Embryonic stem cell and Cortex.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

Keith Pardee;Alexander A. Green;Melissa K. Takahashi;Dana Braff;Dana Braff;Dana Braff.
Cell (2016)

963 Citations

Field-deployable viral diagnostics using CRISPR-Cas13

Cameron Myhrvold;Cameron Myhrvold;Catherine A. Freije;Catherine A. Freije;Jonathan S. Gootenberg;Omar O. Abudayyeh.
Science (2018)

770 Citations

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E

Denis Rousseau;Roger Kaspar;Igor Rosenwald;Lee Gehrke.
Proceedings of the National Academy of Sciences of the United States of America (1996)

562 Citations

Enhanced translation of chimaeric messenger RNAs containing a plant viral untranslated leader sequence

Stephen A. Jobling;Lee Gehrke;Lee Gehrke.
Nature (1987)

431 Citations

Zika virus evolution and spread in the Americas

Hayden C. Metsky;Hayden C. Metsky;Christian B. Matranga;Shirlee Wohl;Shirlee Wohl;Stephen F. Schaffner;Stephen F. Schaffner.
Nature (2017)

342 Citations

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

Charlotte Odendall;Evelyn Dixit;Fabrizia Stavru;Helene Bierne.
Nature Immunology (2014)

334 Citations

Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

Igor B. Rosenwald;Roger Kaspar;Dennis Rousseau;Lee Gehrke.
Journal of Biological Chemistry (1995)

330 Citations

Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

Dina Uzri;Lee Gehrke.
Journal of Virology (2009)

277 Citations

Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase.

Jane-Jane Chen;Mark S. Throop;Lee Gehrke;Irene Kuo.
Proceedings of the National Academy of Sciences of the United States of America (1991)

264 Citations

Induction of Expansion and Folding in Human Cerebral Organoids

Yun Li;Julien Muffat;Attya Omer;Irene Bosch.
Cell Stem Cell (2017)

249 Citations

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