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D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
12463
World Ranking
18839
National Ranking
7697

Overview

Lee Gehrke is affiliated with Harvard University in the United States and conducts research primarily in the field of Medicine, with a focus on Infectious Diseases, Public Health, Environmental and Occupational Health, Molecular Biology, Epidemiology, and Neurology.

The scientist's research covers a range of topics that include:

  • Mosquito-borne diseases and control
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Vectors
  • Viral Infections and Outbreaks Research
  • Inflammasome and immune disorders
  • Long-Term Effects of COVID-19

Among frequently co-authored collaborators are Irene Bosch, Alexsia Richards, Rudolf Jaenisch, Valerie Leger, and Helena de Puig. This highlights a collaborative network across diverse biological and medical research domains.

Lee Gehrke has contributed to multiple research publications, with repeated appearances in venues such as bioRxiv (Cold Spring Harbor Laboratory), iScience, Proceedings of the National Academy of Sciences, Nature Neuroscience, and PLoS Neglected Tropical Diseases.

Selected recent papers include:

  • "FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation," published in 2022 in Nature
  • "A 3D human brain-like tissue model of herpes-induced Alzheimer's disease," published in 2020 in Science Advances
  • "Direct SARS-CoV-2 infection of the human inner ear may underlie COVID-19-associated audiovestibular dysfunction," published in 2021 in Communications Medicine
  • "Targeting stem-loop 1 of the SARS-CoV-2 5' UTR to suppress viral translation and Nsp1 evasion," published in 2022 in Proceedings of the National Academy of Sciences
  • "Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation," published in 2020 in Nature Genetics

The body of work presents consistent engagement with emerging infectious diseases, notably SARS-CoV-2 and other viral pathogens. These studies involve molecular mechanisms, immune responses, and implications for disease clinical outcomes.

Best Publications

  • Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

    Keith Pardee;Alexander A. Green;Melissa K. Takahashi;Dana Braff;Dana Braff;Dana Braff

  • Field-deployable viral diagnostics using CRISPR-Cas13

    Cameron Myhrvold;Cameron Myhrvold;Catherine A. Freije;Catherine A. Freije;Jonathan S. Gootenberg;Omar O. Abudayyeh

  • Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E

    Denis Rousseau;Roger Kaspar;Igor Rosenwald;Lee Gehrke

  • Zika virus evolution and spread in the Americas

    Hayden C. Metsky;Hayden C. Metsky;Christian B. Matranga;Shirlee Wohl;Shirlee Wohl;Stephen F. Schaffner;Stephen F. Schaffner

  • Enhanced translation of chimaeric messenger RNAs containing a plant viral untranslated leader sequence

    Stephen A. Jobling;Lee Gehrke;Lee Gehrke

  • Induction of Expansion and Folding in Human Cerebral Organoids

    Yun Li;Julien Muffat;Attya Omer;Irene Bosch

  • Diverse intracellular pathogens activate type III interferon expression from peroxisomes

    Charlotte Odendall;Evelyn Dixit;Fabrizia Stavru;Helene Bierne

  • Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

    Rajiv K. Khajuria;Rajiv K. Khajuria;Rajiv K. Khajuria;Mathias Munschauer;Jacob C. Ulirsch;Jacob C. Ulirsch;Claudia Fiorini;Claudia Fiorini

  • Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

    Igor B. Rosenwald;Roger Kaspar;Dennis Rousseau;Lee Gehrke

  • Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

    Chun-Wan Yen;Chun-Wan Yen;Helena de Puig;Justina O. Tam;Justina O. Tam;José Gómez-Márquez

  • Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

    Dina Uzri;Lee Gehrke

  • Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase.

    Jane-Jane Chen;Mark S. Throop;Lee Gehrke;Irene Kuo

  • RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling

    Ann Fiegen Durbin;Chen Wang;Joseph Marcotrigiano;Lee Gehrke;Lee Gehrke

  • Magnetization transfer in cartilage and its constituent macromolecules.

    Mit Martha L. Gray Phd;Deborah Burstein;Leann M. Lesperance;Lee Gehrke

  • A 3D human brain-like tissue model of herpes-induced Alzheimer's disease.

    Dana M. Cairns;Nicolas Rouleau;Rachael N. Parker;Katherine G. Walsh

  • Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum

    Irene Bosch;Irene Bosch;Helena de Puig;Megan Hiley;Marc Carré-Camps

  • Surface-Enhanced Raman Spectroscopy-Based Sandwich Immunoassays for Multiplexed Detection of Zika and Dengue Viral Biomarkers

    Maria Sánchez-Purrà;Marc Carré-Camps;Helena de Puig;Irene Bosch

  • Extinction Coefficient of Gold Nanostars.

    Helena de Puig;Justina O. Tam;Justina O. Tam;Chun-Wan Yen;Chun-Wan Yen;Lee Gehrke;Lee Gehrke

  • 5'-conformation of capped alfalfa mosaic virus ribonucleic acid 4 may reflect its independence of the cap structure or of cap-binding protein for efficient translation

    Lee Gehrke;Philip E. Auron;Gary J. Quigley;Alexander Rich

  • Nucleotide sequence and structural determinants of specific binding of coat protein or coat protein peptides to the 3' untranslated region of alfalfa mosaic virus RNA 4.

    F Houser-Scott;M L Baer;K F Liem;J M Cai

Frequent Co-Authors

Vijay G. Sankaran
Vijay G. Sankaran Harvard University
Philip E. Auron
Philip E. Auron Duquesne University
Lanny J. Rosenwasser
Lanny J. Rosenwasser University of Colorado Anschutz Medical Campus
Stuart H. Orkin
Stuart H. Orkin Harvard University
Xiuli An
Xiuli An New York Blood Center
Eric S. Lander
Eric S. Lander Broad Institute
Maurício Lacerda Nogueira
Maurício Lacerda Nogueira Faculdade de Medicina de São José do Rio Preto
Hao Wu
Hao Wu Harvard University
Judy Lieberman
Judy Lieberman Boston Children's Hospital
Pardis C. Sabeti
Pardis C. Sabeti Harvard University

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