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Chemistry

D-Index
66
Citations
14030
World Ranking
7373
National Ranking
2180

Overview

Ercole L. Cavalieri was affiliated with the University of Nebraska Medical Center in the United States. Their research focused primarily on biochemistry, genetics, and molecular biology, with specific contributions in molecular biology and genetics.

The scientist's recent publications reflected a specialized interest in the biochemical mechanisms related to hormone effects and oxidative stress. One notable paper is titled The 3,4-Quinones of Estrone and Estradiol Are the Initiators of Cancer whereas Resveratrol and N-acetylcysteine Are the Preventers, published in 2021 in the International Journal of Molecular Sciences.

Cavalieri collaborated frequently with Eleanor G. Rogan, among others, illustrating a professional network engaged in related scientific inquiries. Their scholarly output was primarily published in the International Journal of Molecular Sciences.

The core topics addressed in their research included:

  • Estrogen and related hormone effects
  • Genomics, phytochemicals, and oxidative stress
  • DNA and nucleic acid chemistry

The detailed focus on estrogen-related hormone effects integrated with explorations into oxidative stress and genomic impacts reflected a multidisciplinary approach bridging molecular pathways with potential disease mechanisms.

Cavalieri's work contributed to the understanding of molecular biology and genetics through investigations into specific biochemical interactions and their implications for cancer initiation and prevention strategies.

Best Publications

  • Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators

    E. L. Cavalieri;D. E. Stack;P. D. Devanesan;R. Todorovic

  • Estrogens as endogenous genotoxic agents--DNA adducts and mutations.

    Ercole Cavalieri;Krystyna Frenkel;Joachim G. Liehr;Eleanor Rogan

  • Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention ☆

    Ercole Cavalieri;Dhubajyoti Chakravarti;Joseph Guttenplan;Elizabeth Hart

  • Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons

    Ercole Cavalieri;Eleanor G Rogan

  • Comparative dose-response tumorigenicity studies of dibenzo[a,l]pyrene versus 7, 12-dimethylbenz[a]anthracene, benzo[a and two dibenzo[a,l]pyrene dihydrodiols in mouse skin and rat mammary gland

    Ercole Cavalieri;S. Higginbotham;N. V S RamaKrishna;P. D. Devanesan

  • Molecular characteristics of catechol estrogen quinones in reactions with deoxyribonucleosides.

    Douglas E. Stack;Jaeman Byun;Michael L. Gross;Eleanor G. Rogan

  • Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7, 12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin

    Sheila Higginbotham;N.V.S. RamaKrishna;Sonny L. Johansson;Eleanor G. Rogan

  • Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases.

    Ercole L. Cavalieri;Kai-Ming Li;Narayanan Balu;Muhammad Saeed

  • The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation.

    Ercole L. Cavalieri;Eleanor G. Rogan

  • Relating aromatic hydrocarbon-induced DNA adducts and c-H-ras mutations in mouse skin papillomas: the role of apurinic sites.

    Dhrubajyoti Chakravarti;Jill C. Pelling;Ercole L. Cavalieri;Eleanor G. Rogan

  • Role of Radical Cations in Aromatic Hydrocarbon Carcinogenesis

    Ercole Cavalieri;Eleanor Rogan

  • Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene.

    Dhrubajyoti Chakravarti;Paula C. Mailander;Kai Ming Li;Sheila Higginbotham

  • Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16[alpha ]-hydroxylation of 17[beta ]-estradiol☆

    Alaa F. Badawi;Ercole L. Cavalieri;Eleanor G. Rogan

  • Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo.

    Kai Ming Li;Rosa Todorovic;Prabu Devanesan;Sheila Higginbotham

  • The Greater Reactivity of Estradiol-3,4-quinone vs Estradiol-2,3-quinone with DNA in the Formation of Depurinating Adducts: Implications for Tumor-Initiating Activity

    Muhammad Zahid;Ekta Kohli;Muhammad Saeed;Eleanor Rogan

  • Synthesis and characterization of estrogen 2,3- and 3,4-quinones. Comparison of DNA adducts formed by the quinones versus horseradish peroxidase-activated catechol estrogens.

    I. Dwivedy;P. Devanesan;P. Cremonesi;E. Rogan

  • Unbalanced metabolism of endogenous estrogens in the etiology and prevention of human cancer

    Ercole L. Cavalieri;Eleanor G. Rogan

  • Catechol estrogen metabolites and conjugates in different regions of the prostate of Noble rats treated with 4-hydroxyestradiol: implications for estrogen-induced initiation of prostate cancer.

    Ercole L. Cavalieri;Prabu Devanesan;Maarten C. Bosland;Alaa F. Badawi

  • Expanded analysis of benzo[a]pyrene-DNA adducts formed in vitro and in mouse skin: their significance in tumor initiation

    Liang Chen;Prabu D. Devanesan;Sheila Higginbotham;Freek Ariese

  • Identification and quantitation of benzo[a]pyrene-DNA adducts formed in mouse skin.

    Eleanor G. Rogan;Prabhakar D. Devanesan;N. V. S. RamaKrishna;Sheila Higginbotham

  • Synthesis and identification of benzo[a]pyrene-guanine nucleoside adducts formed by electrochemical oxidation and by horseradish peroxidase catalyzed reaction of benzo[a]pyrene with DNA

    E. G. Rogan;E. L. Cavalieri;S. R. Tibbels;P. Cremonesi

Frequent Co-Authors

Michael L. Gross
Michael L. Gross Washington University in St. Louis
Ryszard Jankowiak
Ryszard Jankowiak Kansas State University
Gerald J. Small
Gerald J. Small Iowa State University
Ronald L. Cerny
Ronald L. Cerny University of Nebraska–Lincoln
Freek Ariese
Freek Ariese Vrije Universiteit Amsterdam
Alaa Badawi
Alaa Badawi Public Health Agency of Canada
Paola Muti
Paola Muti University of Milan
James N. Ingle
James N. Ingle Mayo Clinic
Kenneth S. Korach
Kenneth S. Korach National Institutes of Health
Ohara Augusto
Ohara Augusto Universidade de São Paulo

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