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Pedro M. Fernandez-Salguero

Pedro M. Fernandez-Salguero

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
18591
World Ranking
9508
National Ranking
179

Overview

Pedro M. Fernandez-Salguero is affiliated with the University of Extremadura in Spain. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus also on Medicine. Within these broader fields, their work further concentrates on subfields such as Molecular Biology, Health, Toxicology and Mutagenesis, Cancer Research, Oncology, and Surgery.

The scientist's research topics cover a variety of areas including:

  • Pluripotent Stem Cells Research
  • Epigenetics and DNA Methylation
  • Toxic Organic Pollutants Impact
  • Effects and risks of endocrine disrupting chemicals
  • Cancer, Hypoxia, and Metabolism
  • Renal and related cancers
  • Hair Growth and Disorders

They have contributed to recent papers such as:

  • Aryl Hydrocarbon Receptor Controls Skin Homeostasis, Regeneration, and Hair Follicle Cycling by Adjusting Epidermal Stem Cell Function, 2021, published in Stem Cells
  • Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor, 2020, published in Epigenetics & Chromatin
  • From Nucleus to Organs: Insights of Aryl Hydrocarbon Receptor Molecular Mechanisms, 2022, published in International Journal of Molecular Sciences
  • Loss of Aryl Hydrocarbon Receptor Favors K-RasG12D-Driven Non-Small Cell Lung Cancer, 2021, published in Cancers
  • Aryl Hydrocarbon Receptor: From Homeostasis to Tumor Progression, 2022, published in Frontiers in Cell and Developmental Biology

Frequent collaborators in their research include Jaime M. Merino, Francisco J. González-Rico, Ana Ordiales-Talavero, Claudia M. Rejano-Gordillo, and Ana Nacarino-Palma. Collaboration with these researchers has been noted multiple times across various publications.

Their studies have often appeared in specific venues with multiple published works in the International Journal of Molecular Sciences, alongside contributions to Stem Cells, Epigenetics & Chromatin, Cancers, and Frontiers in Cell and Developmental Biology.

Best Publications

  • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators.

    S S Lee;T Pineau;J Drago;E J Lee

  • Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

    Pedro Fernandez-Salguero;Thierry Pineau;David M. Hilbert;Timothy McPhail

  • The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

    Shioko Kimura;Yoshinobu Hara;Thierry Pineau;Pedro Fernandez-Salguero

  • Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity

    Pedro M. Fernandez-Salguero;David M. Hilbert;Stuart Rudikoff;Jerrold M. Ward

  • Role of CYP2E1 in the Hepatotoxicity of Acetaminophen

    Susanna S.T. Lee;Jeroen T.M. Buters;Thierry Pineau;Pedro Fernandez-Salguero

  • Genomic instability in Gadd45a- deficient mice

    M. C. Hollander;M. S. Sheikh;D. V. Bulavin;K. Lundgren

  • Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.

    Xiaoxiong Wei;Howard L. McLeod;Julieann McMurrough;Frank J. Gonzalez

  • The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein.

    Robert Barouki;Xavier Coumoul;Pedro M. Fernandez-Salguero

  • Lesions of aryl-hydrocarbon receptor-deficient mice.

    P. M. Fernandez-Salguero;J. M. Ward;J. P. Sundberg;F. J. Gonzalez

  • The Aryl Hydrocarbon Receptor: Studies Using the AHR-Null Mice

    Frank J. Gonzalez;Pedro Fernandez-Salguero

  • Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development.

    Luis M. Esteban;Carlos Vicario-Abejón;Pedro Fernández-Salguero;Alberto Fernández-Medarde

  • A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.

    Fernandez-Salguero P;Hoffman Sm;Cholerton S;Mohrenweiser H

  • Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy.

    Hirokazu Furuya;Pedro Fernandez-salguero;Wendy Gregory;Heather Taber

  • The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle.

    Eulalia Pozo-Guisado;Alberto Alvarez-Barrientos;Sonia Mulero-Navarro;Belen Santiago-Josefat

  • New Trends in Aryl Hydrocarbon Receptor Biology

    Sonia Mulero-Navarro;Pedro M. Fernandez-Salguero

  • Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice.

    Jeffrey M. Peters;Michael G. Narotsky;Guillermo Elizondo;Pedro M. Fernandez-Salguero

  • Targeted Disruption of the Microsomal Epoxide Hydrolase Gene: MICROSOMAL EPOXIDE HYDROLASE IS REQUIRED FOR THE CARCINOGENIC ACTIVITY OF 7,12-DIMETHYLBENZ[a]ANTHRACENE

    Masaaki Miyata;Gen Kudo;Ying-Hue Lee;Tian J. Yang

  • Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis.

    David L. Alexander;Leonardo G. Ganem;Pedro Fernandez-Salguero;Frank Gonzalez

  • Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast.

    Guillermo Elizondo;Pedro Fernandez-Salguero;M. Saeed Sheikh;Geum-Yi Kim

  • The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-beta and apoptosis.

    Hani Zaher;Pedro M. Fernandez-Salguero;John Letterio;M. Saeed Sheikh

Frequent Co-Authors

Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Jerrold M. Ward
Jerrold M. Ward National Institutes of Health
Howard L. McLeod
Howard L. McLeod Utah Tech University
Shioko Kimura
Shioko Kimura National Institutes of Health
Robert Barouki
Robert Barouki Université Paris Cité
Xosé R. Bustelo
Xosé R. Bustelo University of Salamanca
Hannu Raunio
Hannu Raunio University of Eastern Finland
Alvaro Puga
Alvaro Puga University of Cincinnati Medical Center
Harry V. Gelboin
Harry V. Gelboin National Institutes of Health
Angel L. Corbí
Angel L. Corbí Spanish National Research Council

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